{"currentpage":1,"firstResult":0,"maxresult":10,"pagecode":5,"pageindex":{"endPagecode":5,"startPagecode":1},"records":[{"abstractinfo":"采用溶剂浮选分离富集-HPLC测定了茵陈水煎液中的<span style=\"color:red\">滨</span><span style=\"color:red\">蒿</span><span style=\"color:red\">内酯</span>. 考察了浮选溶剂、N2气流速、试液pH值、浮选时间及电解质NaCl等因素对浮选效果的影响,确定了最佳浮选条件. 在最佳条件下加标回收率为92.31%～99.97%,RSD=3.20%,可满足实际样品的分析.","authors":[{"authorName":"刘西茜","id":"b040f597-addd-4d9d-ad0e-6fe455e1e8e1","originalAuthorName":"刘西茜"},{"authorName":"董慧茹","id":"1becee95-7d6b-4748-8904-3744f51ef4d1","originalAuthorName":"董慧茹"},{"authorName":"毕鹏禹","id":"8a4401fc-a1a7-452c-9e7e-4bdea37a1d98","originalAuthorName":"毕鹏禹"}],"doi":"10.3969/j.issn.1000-0518.2009.07.030","fpage":"872","id":"0eaaef81-7d2c-4a10-be67-e614daaf9b63","issue":"7","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"44758510-72e6-4b15-97b5-c598800997b2","keyword":"溶剂浮选","originalKeyword":"溶剂浮选"},{"id":"c1bf02ba-65d6-4a22-b859-ad52f27ecfd4","keyword":"高效液相色谱","originalKeyword":"高效液相色谱"},{"id":"922a1eb1-5b39-4db3-817f-47219b4b0606","keyword":"<span style=\"color:red\">滨</span><span style=\"color:red\">蒿</span><span style=\"color:red\">内酯</span>","originalKeyword":"滨蒿内酯"},{"id":"ce9a44b3-77a3-4065-a56f-927e16697c74","keyword":"茵陈","originalKeyword":"茵陈"}],"language":"zh","publisherId":"yyhx200907030","title":"溶剂浮选-HPLC法测定茵陈水煎液中<span style=\"color:red\">滨</span><span style=\"color:red\">蒿</span><span style=\"color:red\">内酯</span>","volume":"26","year":"2009"},{"abstractinfo":"利用高效液相色谱法对<span style=\"color:red\">蒿</span>甲醚进行了模拟体内酸碱环境的代谢动力学研究,测定了<span style=\"color:red\">蒿</span>甲醚及其代谢产物双氢青蒿素、<span style=\"color:red\">蒿</span>甲醚呋喃酯的代谢曲线。结果表明,<span style=\"color:red\">蒿</span>甲醚在模拟体内肠道和血液的弱碱性环境条件下半衰期为287.2 min(计算值);在模拟体内胃液的酸性环境条件下半衰期为74.6 min;在两种条件下的主要代谢产物均为双氢青蒿素和<span style=\"color:red\">蒿</span>甲醚呋喃酯。该方法克服了以往文献所报道方法的一些缺点,不仅简化了样品制备方法,也提高了检测结果的准确性。","authors":[{"authorName":"陈有根","id":"7b022f76-fdf2-4aeb-8c32-7150b3f6e7aa","originalAuthorName":"陈有根"},{"authorName":"余伯阳","id":"c07f6425-9aa7-432b-8ed6-841f1ed3792d","originalAuthorName":"余伯阳"}],"doi":"10.3321/j.issn:1000-8713.2002.01.008","fpage":"37","id":"12e534a9-b1ae-4e8c-b4e7-477e910cd8da","issue":"1","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"a81019f5-b5a8-475e-8159-b60683b98148","keyword":"高效液相色谱法","originalKeyword":"高效液相色谱法"},{"id":"37626173-1470-4523-bb03-bc8f5001f7f0","keyword":"<span style=\"color:red\">蒿</span>甲醚","originalKeyword":"蒿甲醚"},{"id":"cf0ce384-5fb7-462e-a7fe-7fe0a8a8199a","keyword":"模拟体内酸碱环境","originalKeyword":"模拟体内酸碱环境"},{"id":"986cf242-4908-4f7f-86dc-49185e903467","keyword":"代谢动力学","originalKeyword":"代谢动力学"}],"language":"zh","publisherId":"sp200201008","title":"<span style=\"color:red\">蒿</span>甲醚在模拟体内酸碱环境中的代谢动力学研究","volume":"20","year":"2002"},{"abstractinfo":"报道了抗白血病药物克拉屈<span style=\"color:red\">滨</span>的合成新方法：在NaH作用下，廉价易得的6-氯嘌呤高选择性地在β位和1-氯-2-脱氧-3，5-二-O-对氯苯甲酰基-D-核糖缩合；β-缩合物的2位在三氟乙酸酐和四丁基硝酸铵作用下引入硝基；在NH4 Cl／EtOH作用下，2-硝基转化为2-氯；最后在饱和NH3／CH3 OH溶液中完成保护基脱除和6-氯氨解两步反应，以4步共43.5％的总收率得到抗白血病药物克拉屈<span style=\"color:red\">滨</span>。该方法完全避免了α异构体的生成，原料廉价易得，分离纯化不需柱层析，且反应扩大到100 g规模时，收率无下降，具有较好的应用前景。","authors":[{"authorName":"夏然","id":"58cf0631-ebec-41ea-a002-c389a6386d83","originalAuthorName":"夏然"},{"authorName":"孙莉萍","id":"1df45b35-9ff6-4ed7-b1c3-74c46516f271","originalAuthorName":"孙莉萍"},{"authorName":"渠桂荣","id":"09ce74c7-2e61-428c-b385-ce21ae34eb35","originalAuthorName":"渠桂荣"},{"authorName":"陈磊山","id":"2694a79c-0e3c-48c2-8264-423808611782","originalAuthorName":"陈磊山"}],"doi":"10.11944/j.issn.1000-0518.2016.11.160027","fpage":"1274","id":"f8b86b79-bc8e-42c4-9905-f89d86861850","issue":"11","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"dcadf097-74cf-42ac-94db-37760af279a2","keyword":"氯嘌呤","originalKeyword":"氯嘌呤"},{"id":"95653512-a645-41d5-962a-fe0fe6504d7b","keyword":"克拉屈<span style=\"color:red\">滨</span>","originalKeyword":"克拉屈滨"},{"id":"00ee8895-00bb-46ff-9d54-d781e322a525","keyword":"硝化反应","originalKeyword":"硝化反应"},{"id":"cbaddcf3-4ee7-4676-88e5-05305e878f6d","keyword":"规模合成","originalKeyword":"规模合成"}],"language":"zh","publisherId":"yyhx201611007","title":"抗白血病药物克拉屈<span style=\"color:red\">滨</span>的合成","volume":"33","year":"2016"},{"abstractinfo":"论述<span style=\"color:red\">蒿</span>坪金矿床地质特征、金矿控矿条件及其找矿标志,分析金矿床的控矿因素,对进一步开展找矿具有重要意义.","authors":[{"authorName":"伏雄","id":"9c3bc20f-042e-45d4-be8f-0388961d9545","originalAuthorName":"伏雄"}],"doi":"10.3969/j.issn.1001-1277.2003.08.005","fpage":"16","id":"6eedd711-88bc-4797-a7ea-5376af4badb2","issue":"8","journal":{"abbrevTitle":"HJ","coverImgSrc":"journal/img/cover/HJ.jpg","id":"44","issnPpub":"1001-1277","publisherId":"HJ","title":"黄金"},"keywords":[{"id":"72a3e493-aa73-4f24-88ae-c814a98b312c","keyword":"金矿床","originalKeyword":"金矿床"},{"id":"f96eac38-6c99-4ff9-8f1c-192cabdd5d28","keyword":"地质特征","originalKeyword":"地质特征"},{"id":"e13df6c9-4df1-42a8-87bb-1b03cd1a1abd","keyword":"控矿条件","originalKeyword":"控矿条件"},{"id":"76d01d45-6781-482c-a906-7783323e35da","keyword":"河南<span style=\"color:red\">蒿</span>坪","originalKeyword":"河南蒿坪"}],"language":"zh","publisherId":"huangj200308005","title":"河南<span style=\"color:red\">蒿</span>坪金矿床地质特征及控矿条件分析","volume":"24","year":"2003"},{"abstractinfo":"采用水蒸气蒸馏法提取洞庭湖区野生藜<span style=\"color:red\">蒿</span>和人工种植藜<span style=\"color:red\">蒿</span>的挥发油,用气相色谱-质谱法测定其化学成分和相对含量,发现野生和人工栽培的藜<span style=\"color:red\">蒿</span>挥发油成分差异较大.从野生藜<span style=\"color:red\">蒿</span>馏出物中共鉴定出48种化合物,主要有α-丁香烯(15.734% )、丁香烯(13.246% )、1-甲基-1-乙烯基-2-(1-甲基乙烯基)-4-(1-甲基亚乙烯基)-环己烷(9.511% )和(E)-7,11-二甲基-3-亚甲基-1,6,10-十二碳三烯(5.267% )等;从人工种植藜<span style=\"color:red\">蒿</span>馏出物中共鉴定40种化合物,主要有檀香三烯(13.535% )、α-蒎烯(9.431% )、1-甲基-1-乙烯基-2-(1-甲基乙烯基)-4-(1-甲基亚乙烯基)-环己烷(3.990% )和β-水芹烯(3.048% )等.","authors":[{"authorName":"徐中海","id":"ffc82ea5-a216-4969-a10a-a635bb0f30ba","originalAuthorName":"徐中海"},{"authorName":"吴瑛","id":"1d7a49ef-0613-495d-b884-b29de76de274","originalAuthorName":"吴瑛"},{"authorName":"柳弟贵","id":"eec94241-9245-44b3-b96c-b69f238ec664","originalAuthorName":"柳弟贵"},{"authorName":"陈波","id":"fccbe701-08e0-4c65-a4a5-e58763ff0e85","originalAuthorName":"陈波"}],"doi":"10.3321/j.issn:1000-8713.2007.05.037","fpage":"778","id":"9e87bc72-752a-4827-90d0-3cc66898bd8a","issue":"5","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"29db9f79-65b9-4c00-bb63-1d0ae2ca7b30","keyword":"气相色谱-质谱法(GC-MS)","originalKeyword":"气相色谱-质谱法(GC-MS)"},{"id":"3fa86fd7-9dea-4661-a764-2e9e21f2f142","keyword":"挥发油(essential oil)","originalKeyword":"挥发油(essential oil)"},{"id":"9c03589b-df50-4121-8c9f-2a9a961379e7","keyword":"藜<span style=\"color:red\">蒿</span>(Artemisia selengensis)","originalKeyword":"藜蒿(Artemisia selengensis)"},{"id":"4a0030e7-8d4a-4279-ac50-989f4f19a874","keyword":"水蒸气蒸馏(steam distillation)","originalKeyword":"水蒸气蒸馏(steam distillation)"}],"language":"zh","publisherId":"sp200705037","title":"洞庭湖区藜<span style=\"color:red\">蒿</span>挥发油化学成分的分析","volume":"25","year":"2007"},{"abstractinfo":"以生物相容性好且可生物降解的海藻酸钠（Sodium Alginate,Alg）、几丁聚糖（Chitosan,Chi）为壁材,采用静电液滴装置制备了球形度好、表面光洁、分散性好、平均粒径为210μm的海藻酸钙（Calcium Alginate,Ca-Alg）胶珠,并以卡培他<span style=\"color:red\">滨</span>（CAP）为模型药物,采用一步法和两步法制备了栓塞型载CAP Ca-Alg/Chi微胶囊,并考察了CAP浓度对微胶囊载药量和药物释放的影响。结果表明：随着CAP浓度的增大,载药量增大,包封率却随之减小;微胶囊在0.5 h内的累积释放量不到20%,无突释效应;微胶囊有一定的缓释性能,有望成为一种栓塞型抗肿瘤药物新剂型。","authors":[{"authorName":"孙学战","id":"df60689a-f066-4f17-ae79-6ac228d14da1","originalAuthorName":"孙学战"},{"authorName":"刘源岗","id":"d6e609c3-b062-46a5-a8d6-c87215297886","originalAuthorName":"刘源岗"},{"authorName":"王士斌","id":"dc2584ee-7a6b-4ba5-89c7-917ec950fa1a","originalAuthorName":"王士斌"},{"authorName":"陈爱政","id":"0074644b-d80d-44dd-929d-3fb725e70477","originalAuthorName":"陈爱政"},{"authorName":"骆志勇","id":"421e5783-aa78-408f-a1d1-3f3253789770","originalAuthorName":"骆志勇"}],"doi":"","fpage":"106","id":"408c5d41-d6e8-46fd-b6bb-bc935dadd8a0","issue":"5","journal":{"abbrevTitle":"FHCLXB","coverImgSrc":"journal/img/cover/FHCLXB.jpg","id":"26","issnPpub":"1000-3851","publisherId":"FHCLXB","title":"复合材料学报"},"keywords":[{"id":"33d57e46-aa2d-47a3-b778-d990aa8bb6e0","keyword":"海藻酸钠","originalKeyword":"海藻酸钠"},{"id":"a3cb6fbf-1151-4767-884b-f08dd0f34941","keyword":"几丁聚糖","originalKeyword":"几丁聚糖"},{"id":"dca4ada5-d661-461c-a189-c2aa4f5dd7ee","keyword":"微胶囊","originalKeyword":"微胶囊"},{"id":"4fa3e919-735c-4dbf-8fd5-76d99b120d02","keyword":"卡培他<span style=\"color:red\">滨</span>","originalKeyword":"卡培他滨"},{"id":"9cc776ea-3957-446d-ab60-93de2546fe98","keyword":"缓释","originalKeyword":"缓释"}],"language":"zh","publisherId":"fhclxb201105017","title":"栓塞型载卡培他<span style=\"color:red\">滨</span>微胶囊的性能","volume":"28","year":"2011"},{"abstractinfo":"本发明涉及一种可作为生物医用材料的ε-己<span style=\"color:red\">内酯</span>类聚合物。所说的聚合物以4-羰基-ε-己<span style=\"color:red\">内酯</span>为起始原料，首先将4-羰基-ε-己<span style=\"color:red\">内酯</span>通过均聚，或与ε-己<span style=\"color:red\">内酯</span>、δ-戊<span style=\"color:red\">内酯</span>、丙交酯或乙交酯、或它们的共聚物共聚获得均聚物或共聚物；然后对所获得的均聚物或共聚物进行选择性还原得还原产物，","authors":[],"doi":"","fpage":"16","id":"6f5a425e-bf18-4c8b-8521-5f76e9e2cc61","issue":"8","journal":{"abbrevTitle":"GFZCLKXYGC","coverImgSrc":"journal/img/cover/GFZCLKXYGC.jpg","id":"31","issnPpub":"1000-7555","publisherId":"GFZCLKXYGC","title":"高分子材料科学与工程"},"keywords":[{"id":"f2e07981-8c1b-4f06-ac7c-bcd245f467c4","keyword":"聚合物","originalKeyword":"聚合物"},{"id":"98c7c311-e9c4-4013-8c0d-f3a56e3e2f94","keyword":"<span style=\"color:red\">内酯</span>类","originalKeyword":"内酯类"},{"id":"1f96842c-9470-4c9f-84fb-3e6cd48bd1a9","keyword":"ε-己<span style=\"color:red\">内酯</span>","originalKeyword":"ε-己内酯"},{"id":"069b717f-3787-4c90-8ed2-6a8b2882836b","keyword":"生物医用材料","originalKeyword":"生物医用材料"},{"id":"de153ff2-df04-4dff-a8ba-ff91b3e069df","keyword":"选择性还原","originalKeyword":"选择性还原"},{"id":"bab07836-38d2-4b4c-ab50-f69c2a6a89a3","keyword":"共聚物","originalKeyword":"共聚物"},{"id":"729529c0-cd0a-4f3b-a5dd-0c8b0c578872","keyword":"均聚物","originalKeyword":"均聚物"},{"id":"9b86c68f-e821-4363-853a-275011f60202","keyword":"起始原料","originalKeyword":"起始原料"}],"language":"zh","publisherId":"gfzclkxygc201108005","title":"ε-己<span style=\"color:red\">内酯</span>类聚合物","volume":"27","year":"2011"},{"abstractinfo":"羟基丙烷磺酸<span style=\"color:red\">内酯</span>作为一种重要的有机中间体,在电镀技术中具有重要作用,为此,通过对多条合成路径的对比,探讨了其最佳合成工艺.结果,以丙烯醇为起始原料,经加成、酸化、闭环反应,最后经减压蒸馏,成功制得了羟基丙烷磺酸<span style=\"color:red\">内酯</span>.产品收率在95%以上,可以实现工业化生产.","authors":[{"authorName":"曾超","id":"b702de87-eaea-4651-834f-12c4922b47e5","originalAuthorName":"曾超"},{"authorName":"吕志","id":"53a79952-e42f-45b0-986a-972f11ed2abb","originalAuthorName":"吕志"}],"doi":"10.3969/j.issn.1001-1560.2004.06.010","fpage":"24","id":"7489ef89-10a4-44eb-9e85-e7429a024935","issue":"6","journal":{"abbrevTitle":"CLBH","coverImgSrc":"journal/img/cover/CLBH.jpg","id":"7","issnPpub":"1001-1560","publisherId":"CLBH","title":"材料保护"},"keywords":[{"id":"95406a80-40bd-487f-982a-5194f000d1c6","keyword":"羟基丙烷磺酸<span style=\"color:red\">内酯</span>","originalKeyword":"羟基丙烷磺酸内酯"},{"id":"8c362752-69c4-4a78-a041-bf76406d5d11","keyword":"电镀中间体","originalKeyword":"电镀中间体"},{"id":"a514178d-a5eb-43eb-8f38-4c385ed9914e","keyword":"合成","originalKeyword":"合成"}],"language":"zh","publisherId":"clbh200406010","title":"羟基丙烷磺酸<span style=\"color:red\">内酯</span>的合成工艺","volume":"37","year":"2004"},{"abstractinfo":"研究了己<span style=\"color:red\">内酯</span>开环聚合中聚合时间、聚合温度、及以乙二醇- 钛酸丁酯作为引发剂的用量对聚合物的影响,得出了己<span style=\"color:red\">内酯</span>开环的较佳反应条件(反应温度为140 ℃,反应时间为7 h)并拟合出在该反应条件下聚合产物的分子量与乙二醇的关系式M=150.46(V ρ/m)-0.5315.聚己<span style=\"color:red\">内酯</span>结构用红外、核磁共振和X射线衍射进行表征.","authors":[{"authorName":"胡芸","id":"3beccc96-b8aa-4dbd-afae-6e2e0ed9aa73","originalAuthorName":"胡芸"},{"authorName":"谢凯","id":"17c47799-0d98-488d-a817-f77ab18130b8","originalAuthorName":"谢凯"},{"authorName":"陈一民","id":"80cf93d4-afcd-4789-aade-305fa2efebff","originalAuthorName":"陈一民"},{"authorName":"安立华","id":"938fda53-e9de-49a3-91a3-257ad7e8b5fb","originalAuthorName":"安立华"}],"doi":"","fpage":"48","id":"84ef4816-d88a-437c-ba97-51923ed42b79","issue":"6","journal":{"abbrevTitle":"GFZCLKXYGC","coverImgSrc":"journal/img/cover/GFZCLKXYGC.jpg","id":"31","issnPpub":"1000-7555","publisherId":"GFZCLKXYGC","title":"高分子材料科学与工程"},"keywords":[{"id":"c35e1119-2c72-4d63-beaf-c75a1ee8dc54","keyword":"聚己<span style=\"color:red\">内酯</span>","originalKeyword":"聚己内酯"},{"id":"7efb620f-1932-4bd9-9f73-85bc7d8dd3d5","keyword":"开环聚合","originalKeyword":"开环聚合"},{"id":"e1dcc679-abc2-4caa-9604-0fb9d796d96f","keyword":"生物降解","originalKeyword":"生物降解"},{"id":"b3dcd008-e612-40bb-b0de-b890bd337255","keyword":"合成工艺","originalKeyword":"合成工艺"}],"language":"zh","publisherId":"gfzclkxygc200206012","title":"ε-己<span style=\"color:red\">内酯</span>聚合反应的研究","volume":"18","year":"2002"},{"abstractinfo":"就近年来聚己<span style=\"color:red\">内酯</span>的合成、性能进行了综述,同时介绍了一些关于聚己<span style=\"color:red\">内酯</span>的最新应用研究.","authors":[{"authorName":"於秋霞","id":"595dcaba-9dac-4ecf-857f-3c3d941c6a36","originalAuthorName":"於秋霞"},{"authorName":"朱光明","id":"451ba953-47c7-4895-a8ef-3627155f0519","originalAuthorName":"朱光明"},{"authorName":"梁国正","id":"57ba5de4-9855-4e09-9ab8-3d72c80e937d","originalAuthorName":"梁国正"},{"authorName":"杜宗刚","id":"58a01a7f-18c5-42e0-bfe0-744a04b3307c","originalAuthorName":"杜宗刚"},{"authorName":"宫兆合","id":"68f93e81-1014-4e64-9484-ff7f074039c3","originalAuthorName":"宫兆合"}],"doi":"","fpage":"37","id":"a37cdf83-4206-4b67-9d0c-02164d00bdf2","issue":"5","journal":{"abbrevTitle":"GFZCLKXYGC","coverImgSrc":"journal/img/cover/GFZCLKXYGC.jpg","id":"31","issnPpub":"1000-7555","publisherId":"GFZCLKXYGC","title":"高分子材料科学与工程"},"keywords":[{"id":"407bcfc8-b181-4800-838c-4013bc736081","keyword":"聚己<span style=\"color:red\">内酯</span>","originalKeyword":"聚己内酯"},{"id":"6ca4262f-c632-4eda-af76-aa3b73955036","keyword":"合成","originalKeyword":"合成"},{"id":"e70daac7-d90c-4f2b-b8d4-95abd4488d72","keyword":"开环聚合","originalKeyword":"开环聚合"},{"id":"cf6de260-fcd0-457f-a4b3-a975308da0a6","keyword":"应用","originalKeyword":"应用"}],"language":"zh","publisherId":"gfzclkxygc200405009","title":"聚ε-己<span style=\"color:red\">内酯</span>的合成、性能及应用进展","volume":"20","year":"2004"}],"totalpage":39,"totalrecord":381}