{"currentpage":1,"firstResult":0,"maxresult":10,"pagecode":5,"pageindex":{"endPagecode":5,"startPagecode":1},"records":[{"abstractinfo":"建立了测定人尿液和自来水中4种<span style=\"color:red\">碳</span><span style=\"color:red\">青霉</span><span style=\"color:red\">烯类抗生素</span>（比阿培南、美罗培南、多利培南和厄他培南）的亲水作用色谱方法，所用流动相具有较好的质谱兼容性，可用于色谱?质谱联用。以XAmide为色谱柱，考察了乙腈比例、缓冲盐浓度和pH值对4种<span style=\"color:red\">抗生素</span>保留的影响，提出了可能的保留机理；所发展的方法对目标样品具有良好的线性响应：比阿培南、多利培南和厄他培南的线性范围为0?1～250 mg／L， R2＝0?9999；美罗培南的线性范围为0?5～250 mg／L， R2＝0?9998；4种<span style=\"color:red\">抗生素</span>的定量限（ LOQ）为0?1～0?5 mg／L。尿液样品和自来水样品在5 mg／L和25 mg／L两个水平的加标回收率分别为100?4％～111?9％和79?6％～107?4％，相对标准偏差（ RSD）分别不大于1％和5％。该方法准确、灵敏、简便，可用于人尿液和自来水中多种<span style=\"color:red\">碳</span><span style=\"color:red\">青霉</span><span style=\"color:red\">烯类抗生素</span>的检测。","authors":[{"authorName":"朱银芳","id":"2a3b00af-27d5-44d5-a25e-0cb2f6b8544e","originalAuthorName":"朱银芳"},{"authorName":"纪顺利","id":"aed8e8b7-5f58-4c92-a12c-3e7547093ee2","originalAuthorName":"纪顺利"},{"authorName":"李绍辉","id":"5e314880-b683-4780-937d-8d0f902c152a","originalAuthorName":"李绍辉"},{"authorName":"李成","id":"b4f79f6b-65a5-4d07-8a6e-8b0d9693d316","originalAuthorName":"李成"},{"authorName":"章飞芳","id":"add6bc8d-7442-4720-90d9-d49bf7ffa810","originalAuthorName":"章飞芳"},{"authorName":"梁鑫淼","id":"cc010924-5c40-481b-a8bb-aa51e464b8b5","originalAuthorName":"梁鑫淼"}],"doi":"10.3724/SP.J.1123.2015.05005","fpage":"946","id":"9c90a841-5305-49bc-8719-c37c9fa00cb3","issue":"9","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"6def22f9-ac96-4d00-b2f3-4248af4dc43e","keyword":"亲水作用色谱","originalKeyword":"亲水作用色谱"},{"id":"a708644b-22d4-4fee-a107-fb34b71dc352","keyword":"<span style=\"color:red\">碳</span><span style=\"color:red\">青霉</span><span style=\"color:red\">烯类抗生素</span>","originalKeyword":"碳青霉烯类抗生素"},{"id":"cd4c8a04-0845-4eca-830a-181297f93624","keyword":"尿液","originalKeyword":"尿液"},{"id":"29313b33-89b4-4d3f-808b-99e236b019ee","keyword":"自来水","originalKeyword":"自来水"}],"language":"zh","publisherId":"sp201509010","title":"<span style=\"color:red\">碳</span><span style=\"color:red\">青霉</span><span style=\"color:red\">烯类抗生素</span>亲水作用色谱方法研究及其应用","volume":"","year":"2015"},{"abstractinfo":"建立了液相色谱?质谱测定牛奶中35种四环<span style=\"color:red\">素</span>类、磺胺类、<span style=\"color:red\">青霉</span>素类、大环内酯类、氯霉素类等5<span style=\"color:red\">类抗生素</span>残留的检测方法。样品经碱性乙腈?Mcllvaine缓冲液超声提取，用Eclipse XDB?C8色谱柱（150 mm×2?1 mm，3?5μm）分离，梯度洗脱，流速0?25 mL／min，进样量10μL，采用多反应监测正离子或负离子模式，可以一次性对牛奶中的目标化合物进行定性和定量测定。在优化条件下，35种化合物的检出限均低于10?0μg／kg，方法回收率为70?1％～109?9％，相对标准偏差（ RSD）为2?89％～9?99％。结果表明该方法适用于牛奶中<span style=\"color:red\">抗生素</span>残留的检测。采用所建立的检测方法对市售的50种不同乳品进行了检测，其中一个样品检出氯霉素含量为0?48μg／kg。检测结果表明，中国市场上销售的乳品氯霉素污染的风险仍然存在。本研究建立的液相色谱?质谱联用方法实现了牛奶中35种四环<span style=\"color:red\">素</span>类、磺胺类、<span style=\"color:red\">青霉</span>素类、大环内酯类、氯霉素类等5<span style=\"color:red\">类抗生素</span>残留的测定。该方法简单、快捷、经济，可实现多种<span style=\"color:red\">抗生素</span>残留的快速测定。","authors":[{"authorName":"王浩","id":"5807196a-b97c-4a1d-aca7-dbdfcdbe4eab","originalAuthorName":"王浩"},{"authorName":"赵丽","id":"aef55d9b-f6a7-4afb-a16d-8cf4d41d75c9","originalAuthorName":"赵丽"},{"authorName":"杨红梅","id":"7dd5deb6-2445-4ceb-98b4-e2adf02a0521","originalAuthorName":"杨红梅"},{"authorName":"潘红艳","id":"3e8dd31d-8018-4bd6-99d3-988eeb5a1f14","originalAuthorName":"潘红艳"},{"authorName":"史海良","id":"63b161c5-ec05-456f-b362-b0f0e3ea6728","originalAuthorName":"史海良"},{"authorName":"钱聪","id":"26582d52-af0b-43d1-a670-0b5557711316","originalAuthorName":"钱聪"},{"authorName":"张杉","id":"115b2815-6bc4-4a06-b175-1c3540adbeb3","originalAuthorName":"张杉"}],"doi":"10.3724/SP.J.1123.2015.04046","fpage":"995","id":"a23d8965-3ce6-4605-9b84-3de43e82be48","issue":"9","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"edd351d4-3546-431f-8e06-b83ccf227409","keyword":"液相色谱-串联质谱","originalKeyword":"液相色谱-串联质谱"},{"id":"087c403a-3070-4228-9375-7b00822d8fbc","keyword":"<span style=\"color:red\">抗生素</span>","originalKeyword":"抗生素"},{"id":"94ff4243-cf00-45b4-9dd9-18fd802696ed","keyword":"牛奶","originalKeyword":"牛奶"}],"language":"zh","publisherId":"sp201509017","title":"液相色谱-串联质谱法测定牛奶中35种四环<span style=\"color:red\">素</span>类、磺胺类、<span style=\"color:red\">青霉</span>素类、大环内酯类、氯霉素<span style=\"color:red\">类抗生素</span>残留","volume":"","year":"2015"},{"abstractinfo":"本文从养殖场空气中分离出360株E.coli(大肠杆菌,Escherichia coli),应用肉汤微量稀释法和PCR方法,分离磺胺甲噁唑敏感菌株,检测<span style=\"color:red\">抗生素</span>抗性和抗性基因.在分离的E.coli中,对磺胺甲噁唑敏感菌株为95株(26.4％),有48株含有<span style=\"color:red\">青霉</span>素、氯霉素、四环<span style=\"color:red\">素</span>、环丙沙星、庆大霉素和利福平的抗性,而47株未含有抗性.其中,7株菌株含有1种<span style=\"color:red\">抗生素</span>抗性、11株菌株含有2种<span style=\"color:red\">抗生素</span>抗性、17株菌株含有3种<span style=\"color:red\">抗生素</span>抗性、6株菌株含有4种<span style=\"color:red\">抗生素</span>抗性、4株菌株含有5种<span style=\"color:red\">抗生素</span>抗性、3株菌株含有6种<span style=\"color:red\">抗生素</span>抗性.对<span style=\"color:red\">抗生素</span>的耐受能力依次为:氯霉素、<span style=\"color:red\">青霉</span>素、四环<span style=\"color:red\">素</span>、环丙沙星、庆大霉素、利福平.磺胺甲噁唑敏感菌株共检出163个抗性基因,sul1、int1、sul2、Int2、sul3检出数量依次为49、44、29、20和19;含一种、二种、三种、四种、五种抗性基因菌株分别为45、22、10、7、2;但有6株未检测出抗性基因.结果表明养殖场建场时间、<span style=\"color:red\">抗生素</span>使用、养殖规模等与<span style=\"color:red\">抗生素</span>抗性菌的抗性呈正相关;养殖场空气中分离的E.coli<span style=\"color:red\">抗生素</span>抗性较高,且具有多重抗性;<span style=\"color:red\">抗生素</span>抗性的表现型与其基因型之间出现不完全吻合现象.","authors":[{"authorName":"金明兰","id":"3c2ce192-2559-4d48-9a6b-56c64b1b17d4","originalAuthorName":"金明兰"},{"authorName":"孟庆玲","id":"3a450afe-2f3b-4505-97ad-52f658b2c9c7","originalAuthorName":"孟庆玲"},{"authorName":"赵玉鑫","id":"0d409d3a-1b92-472a-93cd-c62d8309b371","originalAuthorName":"赵玉鑫"},{"authorName":"徐莹莹","id":"9147e2e2-bc22-4517-bb3f-9eb2ec4e1468","originalAuthorName":"徐莹莹"},{"authorName":"薛洪海","id":"389248e5-079c-4cf5-8a32-2012b08d0db9","originalAuthorName":"薛洪海"},{"authorName":"齐子姝","id":"f2fc090c-651b-4609-9f4e-cf8a2b25a221","originalAuthorName":"齐子姝"},{"authorName":"李娜","id":"54314ee5-1780-4c3b-ad27-34b8d7c60689","originalAuthorName":"李娜"},{"authorName":"沈梦楠","id":"64eb6ce3-9d65-4448-86ee-6a7cd101cf36","originalAuthorName":"沈梦楠"},{"authorName":"孙世梅","id":"339d0862-94d9-4a2d-b155-1fb576c5291e","originalAuthorName":"孙世梅"},{"authorName":"金宁一","id":"33cb71b2-07f2-4274-9614-323aa52d7435","originalAuthorName":"金宁一"}],"doi":"10.7524/j.issn.0254-6108.2017.03.2016070102","fpage":"472","id":"9760181f-22a5-4172-8c16-5a83a4c51a80","issue":"3","journal":{"abbrevTitle":"HJHX","coverImgSrc":"journal/img/cover/HJHX.jpg","id":"43","issnPpub":"0254-6108","publisherId":"HJHX","title":"环境化学   "},"keywords":[{"id":"5a04ef0f-cbe2-4bcb-a444-29bdd4f74e07","keyword":"磺胺类抗性菌","originalKeyword":"磺胺类抗性菌"},{"id":"c85784ff-b399-4fe6-afde-e036bd702f3d","keyword":"抗性基因","originalKeyword":"抗性基因"},{"id":"36533f5f-d428-41a1-a7bd-f39b72596f22","keyword":"E.coli","originalKeyword":"E.coli"},{"id":"52d34499-9565-467a-bf32-443360fcb4ae","keyword":"养殖场空气","originalKeyword":"养殖场空气"}],"language":"zh","publisherId":"hjhx201703002","title":"养殖场空气中E.coli磺胺<span style=\"color:red\">类抗生素</span>的抗性","volume":"36","year":"2017"},{"abstractinfo":"建立了同时分离检测牛奶中的氨苄西林、阿莫西林、<span style=\"color:red\">青霉</span>素V和头孢氨苄4种β-内酰胺<span style=\"color:red\">类抗生素</span>的固相萃取-胶束电动色谱法.牛奶样品经沉淀蛋白后,采用HLB固相萃取柱净化浓缩;以含十二烷基硫酸钠(SDS)的磷酸盐为缓冲液,胶束电动色谱分离,210 nm波长下检测.分离电压为18 kV,于9 min内达到基线分离.各组分在0.5～20 mg/L范围内呈良好的线性关系,相关系数(r2)为0.994 3～0.997 6;检出限为0.16～0.20 mg/L;除了阿莫西林外,回收率均大于70%.该方法准确可靠,重复性好,灵敏度高,可以用于牛奶中β-内酰胺<span style=\"color:red\">类抗生素</span>的定量检测.","authors":[{"authorName":"张琦","id":"d18c269d-baaa-4e99-b29b-8ae8123ba625","originalAuthorName":"张琦"},{"authorName":"叶能胜","id":"ad3cb97e-677f-4908-adce-c6e8ea0db935","originalAuthorName":"叶能胜"},{"authorName":"谷学新","id":"019f34ca-ec17-4ae6-9276-76ab392848a9","originalAuthorName":"谷学新"},{"authorName":"郝晓丽","id":"198506f2-6d2e-4fa2-a945-818e0cc88bfd","originalAuthorName":"郝晓丽"},{"authorName":"刘妮","id":"9e65d268-8b17-4639-ba33-8af7baf54edd","originalAuthorName":"刘妮"}],"doi":"10.3321/j.issn:1000-8713.2008.06.007","fpage":"682","id":"b6072824-1216-4dff-88b1-d5081a577542","issue":"6","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"f90f52ff-b8f8-421d-8212-dce112b89664","keyword":"固相萃取","originalKeyword":"固相萃取"},{"id":"ab365007-5654-43ca-aa1e-8cf5eedf1aa8","keyword":"胶束电动色谱","originalKeyword":"胶束电动色谱"},{"id":"4d360e57-cff2-4428-817a-c3f87fd12e2d","keyword":"β-内酰胺<span style=\"color:red\">类抗生素</span>","originalKeyword":"β-内酰胺类抗生素"},{"id":"65b0f55b-3b7b-48fd-b615-bacdbeeda7cf","keyword":"牛奶","originalKeyword":"牛奶"}],"language":"zh","publisherId":"sp200806007","title":"固相萃取-胶束电动色谱法测定牛奶中的4种β-内酰胺<span style=\"color:red\">类抗生素</span>","volume":"26","year":"2008"},{"abstractinfo":"利用高效液相色谱法,在C18柱上以甲醇-乙腈-0.01 mol/L草酸溶液(pH 2.0)(体积比为11∶22∶67)为流动相,采用267 nm紫外光进行检测,在22 min内将7种四环<span style=\"color:red\">素</span><span style=\"color:red\">类抗生素</span>全部洗脱并达到基线分离。探讨了流动相的pH值、草酸的浓度、流动相中有机相的比例以及检测波长等因素对分离度和灵敏度的影响。采用标准加入法定量,对两种实际样品进行了分析。结果表明:该方法操作简单、灵敏度高、定量准确。","authors":[{"authorName":"王蕾","id":"2805de04-e210-458d-89c0-e5e8420a34a8","originalAuthorName":"王蕾"},{"authorName":"张孝松","id":"7b17935f-d263-4f21-9f4d-86b8ab8e7224","originalAuthorName":"张孝松"},{"authorName":"徐智秀","id":"6a6f0199-2799-4b06-9628-b654bea27dbe","originalAuthorName":"徐智秀"},{"authorName":"邵学广","id":"2bbe6bb9-4340-4525-8371-14dcf9e061b4","originalAuthorName":"邵学广"}],"doi":"10.3321/j.issn:1000-8713.2002.01.012","fpage":"49","id":"d8fae4ca-41d3-48eb-9d48-9c09885bdbc3","issue":"1","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"5c9d590f-6487-4713-8c5c-635e36d63b08","keyword":"反相高效液相色谱法","originalKeyword":"反相高效液相色谱法"},{"id":"797487df-28b3-449d-825e-51f11e466049","keyword":"四环<span style=\"color:red\">素</span><span style=\"color:red\">类抗生素</span>","originalKeyword":"四环素类抗生素"},{"id":"d2a04532-9aba-4c13-98b9-86578eca918b","keyword":"紫外检测","originalKeyword":"紫外检测"}],"language":"zh","publisherId":"sp200201012","title":"反相高效液相色谱法测定四环<span style=\"color:red\">素</span><span style=\"color:red\">类抗生素</span>","volume":"20","year":"2002"},{"abstractinfo":"磺胺<span style=\"color:red\">类抗生素</span>(SAs)是水环境中广泛存在的一类新型污染物,因其具有“准”持久性和潜在的生态风险而备受关注.表层水体中,SAs具有多种解离形态,表现为“复合”的光化学行为,从而影响其环境归趋及生态风险.本文总结了水环境中SAs光化学行为研究的最新进展,介绍了该类污染物的直接、间接和自敏化光解动力学,讨论了pH和溶解性物质对其光解动力学的影响机制,评述了其光化学转化路径及羟基自由基氧化机理,简述了该<span style=\"color:red\">类抗生素</span>的光催化降解和光致毒性效应.最后,对SAs的光化学行为研究进行了展望.","authors":[{"authorName":"李军","id":"1579533f-90f1-4142-8748-ba6414afe24c","originalAuthorName":"李军"},{"authorName":"葛林科","id":"57f0e2a4-041f-401c-ac88-feb70167ea17","originalAuthorName":"葛林科"},{"authorName":"张蓬","id":"ae57cf19-6656-4a88-be2c-5be8dd0dce8a","originalAuthorName":"张蓬"},{"authorName":"高会","id":"2713b436-3ab3-49d7-b240-1b6ffbc980a1","originalAuthorName":"高会"},{"authorName":"于春艳","id":"4ff32106-f92b-43d6-ad5d-fda71d13fe95","originalAuthorName":"于春艳"},{"authorName":"那广水","id":"2e4ec453-66d8-43c5-a05d-648e9ea017ab","originalAuthorName":"那广水"}],"doi":"10.7524/j.issn.0254-6108.2016.04.2015111001","fpage":"666","id":"87c40639-d5b5-409b-bdf3-be21071f75d4","issue":"4","journal":{"abbrevTitle":"HJHX","coverImgSrc":"journal/img/cover/HJHX.jpg","id":"43","issnPpub":"0254-6108","publisherId":"HJHX","title":"环境化学   "},"keywords":[{"id":"765a8ced-6add-4bd2-8be3-6ce9087ca94e","keyword":"磺胺<span style=\"color:red\">类抗生素</span>","originalKeyword":"磺胺类抗生素"},{"id":"98e8b19b-2fa5-4f7b-8987-7124b301842e","keyword":"解离形态","originalKeyword":"解离形态"},{"id":"56bd2cb3-0b0a-4990-bc3c-3e2ec2d57b09","keyword":"光化学行为","originalKeyword":"光化学行为"},{"id":"79c0d965-d7e0-47f6-b176-daea9688ba6c","keyword":"转化路径","originalKeyword":"转化路径"},{"id":"425e781f-67b1-465e-b597-be72e642ee79","keyword":"光致毒性","originalKeyword":"光致毒性"}],"language":"zh","publisherId":"hjhx201604008","title":"磺胺<span style=\"color:red\">类抗生素</span>在水环境中的光化学行为","volume":"35","year":"2016"},{"abstractinfo":"磺胺<span style=\"color:red\">类抗生素</span>是人工合成的高效广谱抗菌药,广泛应用于畜牧业、水产养殖业和人类疾病的治疗中.近年来,该物质在环境中被不断检出,并通过饮用水和食物等方式进入食物链,给人类健康带来极大的安全隐患.磺胺<span style=\"color:red\">类抗生素</span>在各种处理工艺和自然环境中均可发生不同程度的降解,但其长期排放和累积残留将诱导磺胺抗性基因的产生,该抗性基因在不同环境介质中可进行传播、扩散,具有比<span style=\"color:red\">抗生素</span>更大的危害性.本文在充分阐述磺胺<span style=\"color:red\">类抗生素</span>在各种环境介质中残留现状的基础上,对其在不同处理工艺和自然环境中的生物降解及其相关抗性基因的污染现状等方面进行了综述,并提出了未来的研究重点和方向.","authors":[{"authorName":"秦丽婷","id":"7e8bd53f-594d-4bba-aedd-6fb5d2d11358","originalAuthorName":"秦丽婷"},{"authorName":"童蕾","id":"67c15c3e-88d5-4d75-a9aa-c475ca678673","originalAuthorName":"童蕾"},{"authorName":"刘慧","id":"4da3fd56-fb64-4ffa-84d8-6872bc6d6626","originalAuthorName":"刘慧"},{"authorName":"关川","id":"fe11b154-4146-4cbb-b978-a8a1767811cc","originalAuthorName":"关川"}],"doi":"10.7524/j.issn.0254-6108.2016.05.2015113004","fpage":"875","id":"d1774ab8-bace-47b4-a536-190ea7d99952","issue":"5","journal":{"abbrevTitle":"HJHX","coverImgSrc":"journal/img/cover/HJHX.jpg","id":"43","issnPpub":"0254-6108","publisherId":"HJHX","title":"环境化学   "},"keywords":[{"id":"ec1de47c-c248-4e4c-a366-4f544480dcad","keyword":"磺胺","originalKeyword":"磺胺"},{"id":"f60c6663-2c5d-4be5-b10a-55b9143a0a15","keyword":"<span style=\"color:red\">抗生素</span>","originalKeyword":"抗生素"},{"id":"1aab17cb-0205-45ce-9ec6-817869a4fb6c","keyword":"处理工艺","originalKeyword":"处理工艺"},{"id":"b1a01869-7507-4d99-be85-d1c864936ce1","keyword":"生物降解","originalKeyword":"生物降解"},{"id":"ce9040d6-ad92-471a-a568-f0a8d710c439","keyword":"抗性基因","originalKeyword":"抗性基因"}],"language":"zh","publisherId":"hjhx201605005","title":"环境中磺胺<span style=\"color:red\">类抗生素</span>的生物降解及其抗性基因污染现状","volume":"35","year":"2016"},{"abstractinfo":"在pH值为3.5～6.0,镧(Ⅲ)-依文思蓝(EB)与硫酸新霉素(NEO)、硫酸卡那霉素(KANA)、硫酸庆大霉(GEN)和硫酸妥布霉素(TOB)等氨基糖苷<span style=\"color:red\">类抗生素</span>反应可生成具有吸收峰和负吸收峰的三元蓝色离子缔合物.其最大吸收波长位于668～674 nm,线性范围从0～1.20×10-5g/mL至0～1.加×10-5g/mL,摩尔吸收光系数(ε)在3.10×104～6.17×104L/(mol@cm)之间;最大负吸收波长位于614～620 nm,线性范围从0～9.00×10-6g/mL至0～1.7×10-5g/mL,摩尔吸收光系数(ε)在4.33×104～1.04×105L/(mol@em).当用正负光吸收叠加时,灵敏度更高.探讨了反应条件、主要分析化学性质及三元缔合物的配合比(LA:EB:GEN=1:2:3).","authors":[{"authorName":"江虹","id":"a06e33d4-4775-410d-8b0a-aea93ff90900","originalAuthorName":"江虹"},{"authorName":"胡小莉","id":"365c6861-c97e-499c-9433-09085618c511","originalAuthorName":"胡小莉"},{"authorName":"刘绍璞","id":"56b1e577-90c8-4abe-92fd-c49a22b504af","originalAuthorName":"刘绍璞"},{"authorName":"秦宗会","id":"917df0ba-8280-43be-8a1a-bbec762bed1d","originalAuthorName":"秦宗会"},{"authorName":"湛海粼","id":"cc1add83-ae3b-46ef-8638-e7c58eb4e3ad","originalAuthorName":"湛海粼"}],"doi":"10.3969/j.issn.1000-0518.2003.09.016","fpage":"883","id":"86ddd538-bdae-44d2-9730-8eba932aea9e","issue":"9","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"fc570f5c-6f28-4551-83cb-6275dd9dd8e5","keyword":"镧(Ⅲ),依文思蓝,氨基糖苷,<span style=\"color:red\">抗生素</span>,分光光度法","originalKeyword":"镧(Ⅲ),依文思蓝,氨基糖苷,抗生素,分光光度法"}],"language":"zh","publisherId":"yyhx200309016","title":"镧-依文思蓝-氨基糖苷<span style=\"color:red\">类抗生素</span>的显色反应及其分析应用","volume":"20","year":"2003"},{"abstractinfo":"建立了高效液相色谱-质谱/质谱测定蜂王浆中5种大环内酯<span style=\"color:red\">类抗生素</span>(螺旋霉素、竹桃霉素、泰乐菌素、罗红霉素、交沙霉素)残留的方法.先用三氯乙酸沉淀蜂王浆中的蛋白质,上层清液再用乙腈提取、C18小柱净化.每种<span style=\"color:red\">抗生素</span>选择一个母离子和两个子离子进行监测.5种大环内酯<span style=\"color:red\">类抗生素</span>在0.002～0.05 mg/L范围内与其峰面积具有良好的线性关系,检测低限均为20μg/kg,3个加标水平(每种<span style=\"color:red\">抗生素</span>的添加水平均为20,100和200μg/kg)下的加标回收率为73.0%～90.2%,相对标准偏差为5.6%～10.5%.","authors":[{"authorName":"谢文","id":"f1e857f0-4110-4502-aa47-3c4e3380928c","originalAuthorName":"谢文"},{"authorName":"丁慧瑛","id":"e6de8754-d317-4a62-b8da-5f5f49aa0b3b","originalAuthorName":"丁慧瑛"},{"authorName":"奚君阳","id":"631159c2-3b81-4f4d-9a40-a7ad29ce7468","originalAuthorName":"奚君阳"},{"authorName":"钱艳","id":"9d18e688-e018-4e6e-a119-fefeb331e731","originalAuthorName":"钱艳"},{"authorName":"黄雷芳","id":"dd8168a7-ace7-4545-bd36-5f7cb95a09c6","originalAuthorName":"黄雷芳"}],"doi":"10.3321/j.issn:1000-8713.2007.03.026","fpage":"404","id":"7525c752-30a3-42f7-8d77-f71547b06242","issue":"3","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"929fd302-0bd8-4110-80da-c37f96d59554","keyword":"高效液相色谱-质谱/质谱法","originalKeyword":"高效液相色谱-质谱/质谱法"},{"id":"a474dd99-fc55-47ec-a670-0c5643ed35ff","keyword":"大环内酯<span style=\"color:red\">类抗生素</span>残留","originalKeyword":"大环内酯类抗生素残留"},{"id":"2bdac9ef-0a4e-46eb-9087-7918242ea616","keyword":"蜂王浆","originalKeyword":"蜂王浆"}],"language":"zh","publisherId":"sp200703026","title":"蜂王浆产品中5种大环内酯<span style=\"color:red\">类抗生素</span>残留量的高效液相色谱-质谱/质谱检测方法","volume":"25","year":"2007"},{"abstractinfo":"建立了磁性固相萃取-高效液相色谱-串联质谱同时测定环境水样中四环<span style=\"color:red\">素</span><span style=\"color:red\">类抗生素</span>的方法。以6种四环<span style=\"color:red\">素</span><span style=\"color:red\">类抗生素</span>（差向四环<span style=\"color:red\">素</span>、土霉素、四环<span style=\"color:red\">素</span>、去甲金霉素、金霉素和脱水四环<span style=\"color:red\">素</span>）为目标化合物，考察并优化了吸附和解吸条件，确定了最佳萃取条件。萃取后的目标化合物经 ZORBAX Eclipse Plus C18柱分离，用高效液相色谱-串联质谱在多反应监测（ MRM）模式下进行检测。在优化的条件下，6种四环<span style=\"color:red\">素</span>在1～100μg／L 范围内线性关系良好，线性相关系数为0.9967～0.9993，检出限为2.44～25.21 ng／L，样品加标回收率为80.6％～90.0％，日内相对标准偏差（ RSDs）为0.6％～2.5％，日间 RSDs为1.1％～7.1％。该方法灵敏度高、背景干扰低，适用于环境水样中6种痕量四环<span style=\"color:red\">素</span><span style=\"color:red\">类抗生素</span>的同时检测。","authors":[{"authorName":"国明","id":"1b4a6dd2-d8e1-4a29-97c0-e7da5e2fc98c","originalAuthorName":"国明"},{"authorName":"于峰","id":"6e448455-b611-4275-97d4-3cc4455ea7b6","originalAuthorName":"于峰"},{"authorName":"贾科玲","id":"538bd000-ae0e-44f0-a12f-03a1b22c2359","originalAuthorName":"贾科玲"},{"authorName":"李姣","id":"a9e321dc-d32b-403a-8735-d2925a09f194","originalAuthorName":"李姣"},{"authorName":"孙海","id":"614453f1-4d33-435a-a8ef-d8bd0da17920","originalAuthorName":"孙海"}],"doi":"10.3724/SP.J.1123.2015.11038","fpage":"407","id":"9117efbc-84ef-4adc-b7a7-107a35fdb68c","issue":"4","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"b777bcf2-66be-4f3c-b1bb-78cc6c64b771","keyword":"磁性固相萃取","originalKeyword":"磁性固相萃取"},{"id":"209f8125-8991-4cba-9d89-1130479bbd85","keyword":"高效液相色谱-串联质谱","originalKeyword":"高效液相色谱-串联质谱"},{"id":"e9cb8acf-7195-4ab5-9c06-d87412ff3153","keyword":"四环<span style=\"color:red\">素</span><span style=\"color:red\">类抗生素</span>","originalKeyword":"四环素类抗生素"},{"id":"212cf739-94a7-483b-8429-508fdf1671e2","keyword":"环境水样","originalKeyword":"环境水样"}],"language":"zh","publisherId":"sp201604009","title":"磁性固相萃取-高效液相色谱-串联质谱法测定环境水样中的四环<span style=\"color:red\">素</span><span style=\"color:red\">类抗生素</span>","volume":"34","year":"2016"}],"totalpage":1461,"totalrecord":14605}