{"currentpage":1,"firstResult":0,"maxresult":10,"pagecode":5,"pageindex":{"endPagecode":5,"startPagecode":1},"records":[{"abstractinfo":"建立了醋酸锌在线衍生高效液相色谱法同时测定血浆中色氨酸(Trp)、犬尿氨酸(Kyn)、<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span><span style=\"color:red\">吲哚</span><span style=\"color:red\">乙酸</span>(<span style=\"color:red\">5</span>-H iaa)和犬尿喹啉酸(Kyna)的方法.以3-硝基酪氨酸为内标(IS),采用Hypersil C-18柱(250 mm×4.0 mm,<span style=\"color:red\">5</span>μm),以250 mmol/L醋酸锌溶液(pH 5.5)-乙腈(95∶<span style=\"color:red\">5</span>,v/v)为流动相,流速为0.8 mL/min,柱温30℃.荧光检测波长设定:<span style=\"color:red\">5</span>-Hiaa为278 nm(λex)/343 nm(λem),Kyna为244 nm(λex)/400 nm(λem);紫外检测波长设定:Kyn和IS为360 nm,Trp为302 nm.4种物质的回收率在91.62％～114.17％之间;线性范围分别为2.50 ～ 320.00μmol/L(Trp),0.32～15.36 μmol/L(Kyn),3.27 ～ 104.60 nmol/L(<span style=\"color:red\">5</span>-Hiaa),14.00 ～ 464.80 nmol/L(Kyna);检出限分别为0.078 μmol/L(Trp),0.056 μmol/L(Kyn),0.690 nmol/L(<span style=\"color:red\">5</span>-Hiaa),1.290 nmol/L(Kyna).利用该方法对30例正常孕妇和28例女性健康志愿者的血浆进行测定,结果表明两组间Trp,Kyn和Kyna含量有显著性差异.该方法操作简便,重复性好,灵敏度高,适合于临床检测.","authors":[{"authorName":"冯成亚","id":"d7aab5d0-8ff3-44c2-a593-9e0f455decec","originalAuthorName":"冯成亚"},{"authorName":"高洁莹","id":"6f8d6239-6a53-4b75-9f07-e330ada5c2ad","originalAuthorName":"高洁莹"},{"authorName":"甄乾娜","id":"4f350e13-c705-4c81-a2ed-cb87db3d7897","originalAuthorName":"甄乾娜"},{"authorName":"樊子勉","id":"bfbadfa3-fe25-4996-aac8-922b971abd94","originalAuthorName":"樊子勉"},{"authorName":"朱明松","id":"27c8f314-f8cb-437b-a3f0-4cc12f9abc0d","originalAuthorName":"朱明松"},{"authorName":"杨香春","id":"cfa9ec21-fa75-488d-939b-63ef95e339ac","originalAuthorName":"杨香春"},{"authorName":"丁敏","id":"848fd695-81f4-4223-b5f3-4e8f2250dce7","originalAuthorName":"丁敏"}],"doi":"10.3724/SP.J.1123.2013.01054","fpage":"577","id":"74cb085a-7062-4ea8-9fd6-e1cadf58d05b","issue":"6","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"49dd9c49-294e-4a6b-ac93-27f3e617530b","keyword":"高效液相色谱法","originalKeyword":"高效液相色谱法"},{"id":"30403a7a-4231-4401-86a4-ac49bf7d0be6","keyword":"色氨酸","originalKeyword":"色氨酸"},{"id":"5abb1f98-2aa1-4a80-a992-621646df0adf","keyword":"犬尿氨酸","originalKeyword":"犬尿氨酸"},{"id":"e8a99b0b-7b89-4ced-878a-dd53676b43f2","keyword":"<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span><span style=\"color:red\">吲哚</span><span style=\"color:red\">乙酸</span>","originalKeyword":"5-羟吲哚乙酸"},{"id":"63459371-15a5-4ea3-944e-af63ba6d6e02","keyword":"犬尿喹啉酸","originalKeyword":"犬尿喹啉酸"},{"id":"fac1dec3-4e7d-4a62-bf45-e7938368c17d","keyword":"血浆","originalKeyword":"血浆"}],"language":"zh","publisherId":"sp201306015","title":"在线衍生-高效液相色谱法同时测定血浆中的色氨酸及其代谢物","volume":"31","year":"2013"},{"abstractinfo":"建立了大鼠脑组织中 6-羟基-1-甲基-1,2,3,4-四氢-β-咔啉(6-OH-MTHβC)、<span style=\"color:red\">5-</span>羟色胺(<span style=\"color:red\">5</span>-HT)和 <span style=\"color:red\">5-</span><span style=\"color:red\">羟</span><span style=\"color:red\">吲哚</span><span style=\"color:red\">乙酸</span>(<span style=\"color:red\">5</span>-HIAA)含量的高效液相色谱-库仑阵列电化学检测(HPLC-ECD)方法.采用的色谱柱为DiscoveryHS F<span style=\"color:red\">5</span>柱(250 mm×4.6 mm,<span style=\"color:red\">5</span> μm),流动相为缓冲液(40 mmol/L柠檬酸+20 mmol/L磷酸氢二钠+0.3 mmol/L乙二胺四<span style=\"color:red\">乙酸</span>二钠,pH 4.0)-甲醇(体积比为78∶22)混合液,流速为1 mL/min.6-OH-MTHβC、<span style=\"color:red\">5</span>-HT、<span style=\"color:red\">5</span>-HIAA在1.0～500.0 μg/L范围内线性关系良好(r>0.9992),检出限分别为0.56,0.26,0.53 μg/L,日内和日间精密度(以相对标准偏差表示)均低于6.1% ,回收率分别为87.1% ～98.2% ,87.0% ～95.3% ,90.1% ～97.7% .用该方法检测新生 7 d 的SD胎鼠脑内6-OH-MTHβC及<span style=\"color:red\">5</span>-HT、<span style=\"color:red\">5</span>-HIAA的含量,发现SD胎鼠在急性酒精中毒 8 h 后6-OH-MTHβC显著上升(P<0.05);而<span style=\"color:red\">5</span>-HT和<span style=\"color:red\">5</span>-HIAA的含量有所下降,但无显著性差异.该法简便、稳定、灵敏度高,适用于测定鼠脑组织中6-OH-MTHβC和<span style=\"color:red\">5</span>-HT,<span style=\"color:red\">5</span>-HIAA含量的相关研究.","authors":[{"authorName":"毛健","id":"90d3dcf2-7d4b-46b7-a6b0-c6b4d44b1995","originalAuthorName":"毛健"},{"authorName":"苏晻","id":"83534dc9-a168-4fd9-a47d-f959557db64c","originalAuthorName":"苏晻"},{"authorName":"栾玉静","id":"054825fa-7b85-4554-bff7-01d28a8a4233","originalAuthorName":"栾玉静"},{"authorName":"陈薛钗","id":"82f3d690-f61f-45bf-9a96-cfc5d6039f88","originalAuthorName":"陈薛钗"},{"authorName":"邓玉林","id":"73d25a6f-2ed2-4dde-8a56-2e89d1e6d3f1","originalAuthorName":"邓玉林"}],"doi":"10.3321/j.issn:1000-8713.2009.02.017","fpage":"216","id":"b1199d3a-8238-456b-bd8e-9647c8aa04bf","issue":"2","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"316cf49d-8cdd-49d6-a70d-290c9eef8d3b","keyword":"高效液相色谱","originalKeyword":"高效液相色谱"},{"id":"9e792733-8804-4883-be36-d6bbf0a78ba5","keyword":"电化学检测","originalKeyword":"电化学检测"},{"id":"df8a876a-059b-47be-8a69-48ae4a1fd963","keyword":"6-羟基-1-甲基-1,2,34-四氢-β-咔啉","originalKeyword":"6-羟基-1-甲基-1,2,34-四氢-β-咔啉"},{"id":"d894c6d0-d2ec-452d-8ab2-ae6c329a89d8","keyword":"<span style=\"color:red\">5-</span>羟色胺","originalKeyword":"5-羟色胺"},{"id":"b5bf5f07-fa87-4fb4-8f38-6395c6c307a4","keyword":"<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span><span style=\"color:red\">吲哚</span><span style=\"color:red\">乙酸</span>","originalKeyword":"5-羟吲哚乙酸"},{"id":"c38038dd-b7c3-4793-abc2-6f5f0c6ae7d8","keyword":"鼠脑","originalKeyword":"鼠脑"}],"language":"zh","publisherId":"sp200902017","title":"鼠脑组织中 6-羟基-1-甲基-1,2,3,4-四氢-β-咔啉及其相关生物胺的高效液相色谱-电化学检测","volume":"27","year":"2009"},{"abstractinfo":"为寻找新型的抗结核化合物,合成了核苷类化合物<span style=\"color:red\">5-</span>[β-(2-<span style=\"color:red\">羟</span>苯基)丙炔酰胺基]-<span style=\"color:red\">5-</span>去氧腺苷. 以邻碘苯酚为原料,经过Sonogashira、缩合等一系列反应合成了该新化合物,并优化了合成反应的条件. 其结构经过红外、核磁共振和高分辨质谱测试技术确证.","authors":[{"authorName":"洪珊珊","id":"1b425b2d-b4eb-4498-92d1-676cb4e7ed83","originalAuthorName":"洪珊珊"},{"authorName":"胡延维","id":"100b41af-7de4-4f96-bfb1-d5043192bfa2","originalAuthorName":"胡延维"},{"authorName":"乔春华","id":"880a16ac-715d-4525-8e58-7deada1edac3","originalAuthorName":"乔春华"}],"doi":"10.3724/SP.J.1095.2010.90345","fpage":"523","id":"cc5f8f79-3a5f-416c-baf0-0269b2aae054","issue":"5","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"128ff849-b862-4cc7-98fc-1ac78e51c8bf","keyword":"MbtA","originalKeyword":"MbtA"},{"id":"550b1801-51f2-435d-87a7-d712002cef25","keyword":"MbtB","originalKeyword":"MbtB"},{"id":"57664495-7060-4fc2-8fd4-0f907b5cfe49","keyword":"抑制剂","originalKeyword":"抑制剂"},{"id":"f4f7e4c3-5276-480c-a5dc-cab0b1597c09","keyword":"核苷类化合物","originalKeyword":"核苷类化合物"},{"id":"092460cd-7178-4f0f-a17b-84eb39bd0e54","keyword":"合成","originalKeyword":"合成"}],"language":"zh","publisherId":"yyhx201005006","title":"<span style=\"color:red\">5-</span>[β-(2-<span style=\"color:red\">羟</span>苯基)丙炔酰胺基]-<span style=\"color:red\">5-</span>去氧腺苷的合成","volume":"27","year":"2010"},{"abstractinfo":"在活性炭负载金属钌(Ru/C)催化剂上实现了<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛的高效选择氧化.以甲苯为反应溶剂,在383 K和2.0MPa O2的反应条件下,2,<span style=\"color:red\">5-</span>呋喃二甲醛(DFF)收率高达95.8％.与活性炭负载的具有相似粒径的Pt,Rh,Pd,Au等其它贵金属催化剂相比,Ru/C具有更加优良的活性和DFF选择性.同时Ru/C催化剂结构稳定,具有良好的重复使用性能.在相似的反应条件下,采用水代替甲苯作为溶剂,同时添加少量水滑石固体碱,可便捷地将主要产物从DFF调变为<span style=\"color:red\">5-</span>甲酰基-2-呋喃甲酸或2,<span style=\"color:red\">5-</span>呋喃二甲酸,显示出Ru/C催化剂在控制<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛选择氧化反应产物方面的优异性能.","authors":[{"authorName":"聂俊芳","id":"c9720963-1842-40b2-8ecc-d56ea5b886a6","originalAuthorName":"聂俊芳"},{"authorName":"解佳翰","id":"16c5c8e6-db17-4081-b1cc-ef2711909b8c","originalAuthorName":"解佳翰"},{"authorName":"刘海超","id":"61e64b6b-6eea-4efe-8e76-914450510a89","originalAuthorName":"刘海超"}],"doi":"10.1016/S1872-2067(12)60551-8","fpage":"871","id":"940e0b7c-8280-445d-a2eb-48c9d2aae7a7","issue":"5","journal":{"abbrevTitle":"CHXB","coverImgSrc":"journal/img/cover/CHXB.jpg","id":"18","issnPpub":"0253-9837","publisherId":"CHXB","title":"催化学报   "},"keywords":[{"id":"33918dd0-9bfc-4a8d-9bc3-8212a25dee15","keyword":"生物质","originalKeyword":"生物质"},{"id":"9ad2b8cf-d559-4c89-90c6-a5cdb06c6ce0","keyword":"<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛","originalKeyword":"5-羟甲基糠醛"},{"id":"377adce0-3b10-4453-b467-7f2d910e637b","keyword":"2,<span style=\"color:red\">5-</span>呋喃二甲醛","originalKeyword":"2,5-呋喃二甲醛"},{"id":"275dbf61-8f04-41ff-b338-5cae47698d05","keyword":"选择氧化","originalKeyword":"选择氧化"},{"id":"41afe609-d4f8-4caf-94f4-e74de40ba764","keyword":"钌催化剂","originalKeyword":"钌催化剂"}],"language":"zh","publisherId":"cuihuaxb201305007","title":"Ru/C催化<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛选择氧化高效合成2,<span style=\"color:red\">5-</span>呋喃二甲醛","volume":"34","year":"2013"},{"abstractinfo":"以活性炭负载金属钌(Ru/C)为催化剂,在碱性水溶液中研究了<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛(HMF)选择氧化反应。与MgO, Ca(OH)2和NaOH相比,加入具有合适碱强度的镁铝水滑石有利于生成<span style=\"color:red\">5-</span>甲酰基-2-呋喃甲酸(FFCA)或2,<span style=\"color:red\">5-</span>呋喃二甲酸(FDCA)。 X射线光电子能谱实验表明金属态的钌是活性催化中心。同位素示踪结果则表明水而非氧气提供了<span style=\"color:red\">5-</span>甲酰基-2-呋喃甲酸及2,<span style=\"color:red\">5-</span>呋喃二甲酸等羧酸产物的氧源。根据这些结果,并结合HMF和2,<span style=\"color:red\">5-</span>呋喃二甲醛氧化的动力学研究,我们提出HMF选择性氧化制备FFCA遵循Langmuir-Hinshelwood反应机理。其中, HMF在金属Ru表面饱和解离吸附,在解离吸附的氧原子的协助下发生β-脱氢生成2,<span style=\"color:red\">5-</span>呋喃二甲醛(DFF)吸附物种。该DFF物种进一步发生水合与氧化形成FFCA产物。","authors":[{"authorName":"解佳翰","id":"91c75802-a454-4dfa-a2aa-b76f0529574e","originalAuthorName":"解佳翰"},{"authorName":"聂俊芳","id":"69747aa0-e1dc-404b-a68f-b0036a3030d8","originalAuthorName":"聂俊芳"},{"authorName":"刘海超","id":"b5af9850-0779-4b22-a39b-a9f3795d0c6b","originalAuthorName":"刘海超"}],"doi":"10.1016/S1872-2067(14)60136-4|","fpage":"937","id":"7ea41d97-78dc-439f-a592-8b0f4785af3a","issue":"6","journal":{"abbrevTitle":"CHXB","coverImgSrc":"journal/img/cover/CHXB.jpg","id":"18","issnPpub":"0253-9837","publisherId":"CHXB","title":"催化学报   "},"keywords":[{"id":"4a5f6a20-8d64-4422-9afe-a5eab82d8682","keyword":"<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛","originalKeyword":"5-羟甲基糠醛"},{"id":"af70647d-e714-43ba-9ed5-eadcfd1091b7","keyword":"氧化反应","originalKeyword":"氧化反应"},{"id":"a7abfb9f-dd69-4f14-a71f-5140fce8444d","keyword":"2,<span style=\"color:red\">5-</span>呋喃二甲醛","originalKeyword":"2,5-呋喃二甲醛"},{"id":"7ee5ca97-742d-45e3-9894-395edebc153c","keyword":"<span style=\"color:red\">5-</span>甲酰基-2-呋喃甲酸","originalKeyword":"5-甲酰基-2-呋喃甲酸"},{"id":"5dd79467-60bd-4065-af8b-95a3050f6484","keyword":"镁铝水滑石","originalKeyword":"镁铝水滑石"},{"id":"aa225ca7-ca96-48d2-b1b2-e6fb51664f66","keyword":"钌基催化剂","originalKeyword":"钌基催化剂"},{"id":"56788cc8-12ee-4659-8f98-3f5da78b6fc5","keyword":"反应机理","originalKeyword":"反应机理"}],"language":"zh","publisherId":"cuihuaxb201406021","title":"碱性条件下Ru/C催化<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛选择氧化反应","volume":"","year":"2014"},{"abstractinfo":"为了考察药物<span style=\"color:red\">5-</span>氟尿嘧啶(<span style=\"color:red\">5</span>-Fu)与<span style=\"color:red\">吲哚</span>美辛(IDMC)的协同作用,采用超临界流体强制分散溶液技术(SEDS),以二氯甲烷/二甲亚砜为共溶剂,制备了复合<span style=\"color:red\">5</span>-Fu和IDMC的L-聚乳酸(PLLA)微球.利用单因素法探索了制备复合微球的最佳外部条件,通过表面形貌、载药量、粒径分布、释放性能的检测和体外细胞实验来表征微球的各项性能.结果表明:当共溶剂二氯甲烷/二甲亚砜比例为30:1时,制备该微球的优化条件为39℃、14 MPa;微球形貌呈类球形,粒径分布在0.5～<span style=\"color:red\">5</span>μm;复合IDMC后微球具有更优良的缓释效果;载药微球对A549细胞系增殖有明显的抑制作用,但与复合IDMC前后微球共培养的2组细胞的相对生长速率(RGR)无显著性差异.","authors":[{"authorName":"张严之","id":"937485d9-a424-44fb-86d8-ee4a35e3ee58","originalAuthorName":"张严之"},{"authorName":"李奎锋","id":"ae03e14e-4569-4b43-8906-97e98fd5c211","originalAuthorName":"李奎锋"},{"authorName":"黄婷","id":"1ed4135c-ddc6-4d02-8d67-aa957772529d","originalAuthorName":"黄婷"},{"authorName":"黄锐","id":"164e6c0e-d104-498a-8566-d6f7ed8d49a0","originalAuthorName":"黄锐"},{"authorName":"康云清","id":"a7e27131-0d08-4969-a7d6-4cc2cef4cebc","originalAuthorName":"康云清"},{"authorName":"尹光福","id":"4d206b92-cfa7-4582-b4af-a05bb33a52f8","originalAuthorName":"尹光福"}],"doi":"","fpage":"21","id":"2be8be7e-2f56-4c43-ac64-15a364e1e6e4","issue":"1","journal":{"abbrevTitle":"FHCLXB","coverImgSrc":"journal/img/cover/FHCLXB.jpg","id":"26","issnPpub":"1000-3851","publisherId":"FHCLXB","title":"复合材料学报"},"keywords":[{"id":"3bc2bc35-4cf8-4847-809f-de57df6e4c73","keyword":"超临界流体技术","originalKeyword":"超临界流体技术"},{"id":"672a6e50-0dfd-46d4-84cd-fd193466b522","keyword":"<span style=\"color:red\">5-</span>氟尿嘧啶","originalKeyword":"5-氟尿嘧啶"},{"id":"c7bc2594-d0c6-4c8d-8040-bff74bd21b48","keyword":"<span style=\"color:red\">吲哚</span>美辛","originalKeyword":"吲哚美辛"},{"id":"92a37533-a186-481c-8ab9-911854530733","keyword":"聚乳酸","originalKeyword":"聚乳酸"},{"id":"e3d67c7c-8c4d-445e-b53e-58b86be8fc26","keyword":"微球","originalKeyword":"微球"}],"language":"zh","publisherId":"fhclxb201101004","title":"超临界流体技术制备<span style=\"color:red\">5-</span>氟尿嘧啶-<span style=\"color:red\">吲哚</span>美辛-聚乳酸缓释微球","volume":"28","year":"2011"},{"abstractinfo":"以<span style=\"color:red\">5</span>-Cl水杨醛和L-苯丙氨酸、L-亮氨酸及L-甘氨酸的脂肪酸酯为原料,通过碱催化的席夫碱缩合反应,合成了6种N-(<span style=\"color:red\">5-</span>氯-2-<span style=\"color:red\">羟</span>苄基)席夫碱氨基酸酯及其还原产物N-(<span style=\"color:red\">5-</span>氯-2-<span style=\"color:red\">羟</span>苄基)氨基酸酯. 化合物的结构及组成经过IR、1H NMR和元素分析测试技术进行了表征. 合成的席夫碱及其还原产物对革兰氏阴性菌、革兰氏阳性菌及真菌均有不同程度的抑制作用. 质量分数为0.01%的N-(<span style=\"color:red\">5-</span>氯-2-<span style=\"color:red\">羟</span>苄基)席夫碱氨基酸酯对大肠杆菌的抑菌率达90%以上,而N-(<span style=\"color:red\">5-</span>氯-2-<span style=\"color:red\">羟</span>苄基)氨基酸酯对金黄色葡萄球菌的抑菌率也在90%以上,均为强抑菌活性,其中N-(<span style=\"color:red\">5-</span>氯-2-<span style=\"color:red\">羟</span>苄基)苯丙氨酸酯的抑菌率达98%以上.","authors":[{"authorName":"刘倩","id":"2ce08d23-467c-491b-979f-80a288da8c7d","originalAuthorName":"刘倩"},{"authorName":"卢俊瑞","id":"b91e586b-06e6-407e-8a34-c7d9441fd880","originalAuthorName":"卢俊瑞"},{"authorName":"辛春伟","id":"818a73b0-9e93-42c5-a111-fadc49075440","originalAuthorName":"辛春伟"},{"authorName":"鲍秀荣","id":"1ef874ff-2e71-4a3b-8edb-e2953fdc1146","originalAuthorName":"鲍秀荣"},{"authorName":"刘玉清","id":"5d8c8c83-3112-42e5-a277-237e0301ff66","originalAuthorName":"刘玉清"},{"authorName":"朱姗姗","id":"fcf53a18-c280-4a2e-bcb4-8cce826f53d6","originalAuthorName":"朱姗姗"},{"authorName":"邹敏","id":"2da55d90-6607-4f6d-b15e-b7dc97e62556","originalAuthorName":"邹敏"}],"doi":"10.3724/SP.J.1095.2010.90765","fpage":"1012","id":"70e52c0c-4531-42da-85c0-01b9ad581a99","issue":"9","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"4205575c-b5c4-4c8a-89c4-6e22fa931de8","keyword":"N-(氯<span style=\"color:red\">羟</span>苯基)席夫碱氨基酸酯","originalKeyword":"N-(氯羟苯基)席夫碱氨基酸酯"},{"id":"ac09e743-9af7-4f1d-9d79-e2cb55909301","keyword":"N-(氯<span style=\"color:red\">羟</span>苯基)氨基酸酯","originalKeyword":"N-(氯羟苯基)氨基酸酯"},{"id":"29328e15-b208-4774-a52b-c205c63df280","keyword":"合成","originalKeyword":"合成"},{"id":"a995d8d8-4e4d-4e59-ae97-74c288cd5f8c","keyword":"抑菌活性","originalKeyword":"抑菌活性"}],"language":"zh","publisherId":"yyhx201009005","title":"N-(<span style=\"color:red\">5-</span>氯-2-<span style=\"color:red\">羟</span>苄基)氨基酸酯的合成、表征及抑菌活性","volume":"27","year":"2010"},{"abstractinfo":"研究了碱金属卤化物对AlCl3催化葡萄糖转化制备<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛(HMF)的促进作用。结果表明, NaF对反应有显著抑制作用,而NaI和NaBr对反应有显著促进作用,而且NaI比NaBr的促进效果更明显。在N,N-二甲基乙酰胺(DMAC)中,以NaI为添加剂,130oC反应15 min, AlCl3催化葡萄糖转化制备HMF,葡萄糖转化率由71%提高到86%, HMF收率由36%提高到62%。 AlCl3-NaI-DMAC体系也可用于果糖、甘露糖等单糖,蔗糖、麦芽糖、纤维二糖等二糖,以及菊粉等多糖的转化。以蔗糖为原料, HMF收率可达63%。","authors":[{"authorName":"任秋鹤","id":"85c78196-11ed-4b52-add7-7c5813aec15f","originalAuthorName":"任秋鹤"},{"authorName":"黄义争","id":"269704ec-6291-4a5a-b1f5-fbcb001c8710","originalAuthorName":"黄义争"},{"authorName":"马红","id":"7f516b86-d5af-4204-9a49-10e3b301fb99","originalAuthorName":"马红"},{"authorName":"高进","id":"1845b0ac-e738-481f-9ac6-732bf6c650bf","originalAuthorName":"高进"},{"authorName":"徐杰","id":"b0ea4ac1-f622-4ac6-9258-f969df677992","originalAuthorName":"徐杰"}],"doi":"10.1016/S1872-2067(14)60012-7","fpage":"496","id":"b8e95645-d213-4a39-b639-193f59b8f0a8","issue":"4","journal":{"abbrevTitle":"CHXB","coverImgSrc":"journal/img/cover/CHXB.jpg","id":"18","issnPpub":"0253-9837","publisherId":"CHXB","title":"催化学报   "},"keywords":[{"id":"6b9a13a3-49ac-486f-b89d-daa8b18b1c50","keyword":"糖类化合物","originalKeyword":"糖类化合物"},{"id":"696a314c-40cd-40af-9720-88d15eab9fc2","keyword":"<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛","originalKeyword":"5-羟甲基糠醛"},{"id":"ac2b4f30-b0fc-4a2d-8d0a-b2e8c86ef0fd","keyword":"金属卤化物","originalKeyword":"金属卤化物"},{"id":"2099cfc1-a319-4b6b-8f56-94ea2e430979","keyword":"催化","originalKeyword":"催化"}],"language":"zh","publisherId":"cuihuaxb201404008","title":"金属卤化物促进糖类催化转化制备<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛","volume":"","year":"2014"},{"abstractinfo":"制备了多种离子液体,并将其作为催化剂和溶剂催化果糖脱水制备<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛(HMF).制备的酸性离子液体包括磺酸基功能化酸性离子液体、咪唑类酸性离子液体和吡啶类酸性离子液体.利用核磁共振仪和红外光谱仪对离子液体的结构进行表征.利用紫外可见光分光光度计结合Hammett指示剂计算Hammett酸度函数,比较了酸强度的大小对反应的影响.结果表明,离子液体的酸强度对反应有较大影响,在无其它催化剂和溶剂的情况下,离子液体具有较高的催化活性,通过使用1-丁基-3..甲基咪唑氯盐(BmimCl)作为催化剂,当反应温度为120℃,反应进行到4h时,HMF收率可以达到74.97％.","authors":[{"authorName":"王福余","id":"b465626c-8f54-4597-9cc4-093f745704a1","originalAuthorName":"王福余"},{"authorName":"刘艳丽","id":"db842e65-7210-4e02-8a5c-17bf94f4ec89","originalAuthorName":"刘艳丽"},{"authorName":"王崇","id":"763a8eb3-6b98-4d1b-a334-26151c5a0eb0","originalAuthorName":"王崇"},{"authorName":"赵振波","id":"dae5716f-c741-4536-bedd-a37bb84b47d9","originalAuthorName":"赵振波"}],"doi":"10.3724/SP.J.1095.2014.30316","fpage":"424","id":"aaa3f296-86ff-40f0-870d-593201c6ff21","issue":"4","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"461465c3-7f54-4e84-b98b-451bc21dff39","keyword":"酸性离子液体","originalKeyword":"酸性离子液体"},{"id":"fdd4278d-2eb2-4268-9a53-d64be13f8575","keyword":"果糖","originalKeyword":"果糖"},{"id":"3dbcaaea-feca-42b4-a5f5-d53d10089966","keyword":"<span style=\"color:red\">羟</span>甲基糠醛","originalKeyword":"羟甲基糠醛"},{"id":"934d0a1c-497d-4680-ab50-ff51278edcd5","keyword":"Hammett酸函数","originalKeyword":"Hammett酸函数"}],"language":"zh","publisherId":"yyhx201404009","title":"酸性离子液体中果糖脱水制备<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛","volume":"31","year":"2014"},{"abstractinfo":"以离子液体1-丁基-3-甲基咪唑氯为溶剂,以CrCl3·6H2O为催化剂,直接转化纤维素生成<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛(HMF).考察了微波辐射条件、反应温度、反应时间及催化剂用量对HMF产率的影响.结果表明,在最佳条件下,HMF产率可达55%.","authors":[{"authorName":"吴树昌","id":"119b4c53-d335-4a87-bec1-0bcd504c239c","originalAuthorName":"吴树昌"},{"authorName":"王春雷","id":"6998d1f0-dc34-4b98-ba94-06c3d4794cbf","originalAuthorName":"王春雷"},{"authorName":"高勇军","id":"0fdcb014-2c24-4b95-870f-aec2a720bc37","originalAuthorName":"高勇军"},{"authorName":"张少春","id":"1a94845e-e94d-4748-bd11-cf49a760066b","originalAuthorName":"张少春"},{"authorName":"马丁","id":"fa89f8b2-9636-49f3-843f-a8ad8b506b05","originalAuthorName":"马丁"},{"authorName":"赵宗保","id":"ad38c048-d38d-4c6b-9184-01eb7c718559","originalAuthorName":"赵宗保"}],"doi":"10.3724/SP.J.1088.2010.00149","fpage":"1157","id":"030566d7-db26-4e17-b749-4b51e085c6de","issue":"9","journal":{"abbrevTitle":"CHXB","coverImgSrc":"journal/img/cover/CHXB.jpg","id":"18","issnPpub":"0253-9837","publisherId":"CHXB","title":"催化学报   "},"keywords":[{"id":"f63a61da-dfb8-4709-9e01-c22de10eadf1","keyword":"离子液体","originalKeyword":"离子液体"},{"id":"55a65c08-bb6e-4ab1-839f-5a6a91846ef4","keyword":"微波","originalKeyword":"微波"},{"id":"082843b3-444a-43c8-a80d-eee7ce174bd4","keyword":"Lewis酸","originalKeyword":"Lewis酸"},{"id":"6654aa9c-b175-4bf2-9cb9-f50b9be3af88","keyword":"纤维素","originalKeyword":"纤维素"},{"id":"26bae453-20e6-47dd-b136-5e70ed77809c","keyword":"<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛","originalKeyword":"5-羟甲基糠醛"}],"language":"zh","publisherId":"cuihuaxb201009012","title":"离子液体中微波辅助的Lewis酸催化纤维素制备<span style=\"color:red\">5-</span><span style=\"color:red\">羟</span>甲基糠醛","volume":"31","year":"2010"}],"totalpage":2757,"totalrecord":27568}