Calcium Phosphate Coating over Silk Fibroin Film by Biomimetic Methods

武汉理工大学学报-材料科学版(英文版), 2005, 20(z1): 92-94.

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1.West China College of Stomatology,Sichuan University,Chengdu 610041,China

2.West China College of Stomatology,Sichuan University,Chengdu 610041,China

3.West China College of Stomatology,Sichuan University,Chengdu 610041,China

4.West China College of Stomatology,Sichuan University,Chengdu 610041,China

5.West China College of Stomatology,Sichuan University,Chengdu 610041,China

6.Key Laboratory of Oral Biomedical Engineering,Sichuan University,Chengdu 610041,China

7.Department of Biomedical Engineering and Orthopedic Surgery,University of Tennessee Health Science Center,Memphis 38163,USA

8.Department of Biomedical Engineering and Orthopedic Surgery,University of Tennessee Health Science Center,Memphis 38163,USA

9.West China College of Stomatology,Sichuan University,Chengdu 610041,China

Calcium Phosphate Coating over Silk Fibroin Film by Biomimetic Methods

Keywords： biomineralization

To investigate the biomineralization behavior of silk fibroin and to valuate the biodegradation and biocompatibility of the hybrid biomaterial, the calcium phosphate deposits were identified with SEM, EDX,XRD and FTIR. The results reveal that supersaturated calcification solution is an effective method for the mineralization of fibroin film. Enzymatic degradation experiment demonstrates the biodegradability of the composites. Osteoblasts incubation shows an excellent cytocompatibility on the mineralized fibroin films.

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Calcium Phosphate Coating over Silk Fibroin Film by Biomimetic Methods

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