采用改进的化学共沉淀法制备了镝掺杂铁氧体磁流体DyxFe3-xO4,然后以甲基丙烯酸聚乙二醇酯(PEGMA)为单体,N,N’-亚甲基双丙烯酰胺(MBA)为交联剂,采用光化学方法在DyxFe3-xO4磁流体中制备了磁性甲基丙烯酸聚乙二醇酯微球,进而合成了含有稀土元素Tb的荧光磁性高分子微球(FMPMs).用VSM、PCS、FTIR、TGA、SEM、FS等技术对FMPMs的性能进行了表征,并以丝裂霉素C(MitomycinC,MMC)为药物模型,初步考察了FMPMs对MMC的载释性能.结果表明,荧光磁性高分子微球粒径较小,呈圆球形,具有超顺磁性和荧光性,分散性好；同时具有较高的载药量和包封率,体外药物释放受pH值影响较大,是靶向给药的良好载体.
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