壳聚糖是天然多糖类高分子化合物甲壳素的脱乙酰产物,具有良好的生物相容性、可降解性和生物活性,可作为骨修复材料,并可应用于骨组织工程材料中的三维生长支架,作为种子细胞或活性生长因子的生物载体材料.综述了壳聚糖类复合材料在骨填充修复材料、骨组织工程和软骨组织工程方面应用的状况及前景.
参考文献
| [1] | 蒋挺大.壳聚糖[M].北京:化学工业出版社,2001 |
| [2] | Majeti N.V. Ravi Kumar .A review of chitin and chitosan applications[J].Reactive & functional polymers,2000(1):1-27. |
| [3] | Felse P A;Panda T .Studies on application of chitin and its derivatives[J].Bioprocess Engineering,1999,20:505. |
| [4] | Shahidi F.;Arachchi JKV.;Jeon YJ. .Food applications of chitin and chitosans [Review][J].Trends in food science & technology,1999(2):37-51. |
| [5] | Mattioli B M;Muzzarelli B;Muzzarelli R A A .Chitin and chitosan in wound healing and other biomedical applications[J].Carbohydr Europe,1997,19:30. |
| [6] | Madihally SV;Matthew HW .Porous chitosan scaffolds for tissue engineering.[J].Biomaterials,1999(12):1133-1142. |
| [7] | Suh JK;Matthew HW .Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering: a review.[J].Biomaterials,2000(24):2589-2598. |
| [8] | Leroux L;Hatim Z;Freche M et al.Effects of various adjuvants (lactic acid, glycerol, and chitosan) on the injectability of a calcium phosphate cement[J].Bone,1999,25(02):31S. |
| [9] | Khairoun I;Driessens FC;Boltong MG;Planell JA;Wenz R .Addition of cohesion promotors to calcium phosphate cements.[J].Biomaterials,1999(4):393-398. |
| [10] | Takechi M .Fabrication and biocompatibility of antiwashout type fast-setting calcium cement using chitosan[J].Shikoku shigakkai Zasshi,1998,11(01):161. |
| [11] | Takechi M;Miyamoto Y;Ishikawa K;Toh T;Yuasa T;Nagayama M;Suzuki K .Initial histological evaluation of anti-washout type fast-setting calcium phosphate cement following subcutaneous implantation.[J].Biomaterials,1998(22):2057-2063. |
| [12] | Yokoyama A;Yamamoto S;Kawasaki T;Kohgo T;Nakasu M .Development of calcium phosphate cement using chitosan and citric acid for bone substitute materials.[J].Biomaterials,2002(4):1091-1101. |
| [13] | Wang X;Ma J;Feng Q;Cui F .Skeletal repair in rabbits with calcium phosphate cements incorporated phosphorylated chitin.[J].Biomaterials,2002(23):4591-4600. |
| [14] | Muzzarelli R A A;Ramos V;Stanic V et al.Ostteogenesis promoted by calcium phosphate N, N-dicarboxymethyl chitosan[J].Carbohydrate Polymers,1998,36:267. |
| [15] | Viala S.;Lacout JL.;Freche M. .Preparation of a new organic-mineral composite: Chitosan-hydroxyapatite[J].Annales de Chimie-Science des Materiaux,1998(1/2):69-72. |
| [16] | Menon P R;Napper S A;Mukherjee D P.Development of a composite of hydroxyapatite and chitosan as a bone graft substitute[M].Southern Biomedical Engineering ConferenceProceedings,1995:95. |
| [17] | Yamaguchi I;Tokuchi K;Fukuzaki H.Preparation and mechanical properties of chitosan/hydroxyapatite nanocomposites[J].Key Engineering Materials,2001(192-195):673. |
| [18] | Khor E;Wan A C A;Hastings W .Method of preparing filler containing forms of citin[P].US:5821285,1998. |
| [19] | Andrew CA;Khor E;Hastings GW .The influence of anionic chitin derivatives on calcium phosphate crystallization.[J].Biomaterials,1998(14):1309-1316. |
| [20] | Varma HK;Yokogawa Y;Espinosa FF;Kawamoto Y;Nishizawa K;Nagata F;Kameyama T .Porous calcium phosphate coating over phosphorylated chitosan film by a biomimetic method.[J].Biomaterials,1999(9):879-884. |
| [21] | Marler J J;Upton J;Langer R et al.Transplantation of cells in matrics for tissue regeneration[J].Advanced Drug Delivery Reviews,1998,33(1-2):165. |
| [22] | Hutmacher DW .Scaffolds in tissue engineering bone and cartilage.[J].Biomaterials,2000(24):2529-2543. |
| [23] | Ang T H;Sultana F S A;Hutmacher D W et al.Fabrication of 3D chitosan-hydroxyapatite scaffolds using a robotic dispensing system[J].Materials Science and Engineering,2002,20:35. |
| [24] | Zhang Y.;Zhang MQ. .Microstructural and mechanical characterization of chitosan scaffolds reinforced by calcium phosphates[J].Journal of Non-Crystalline Solids: A Journal Devoted to Oxide, Halide, Chalcogenide and Metallic Glasses, Amorphous Semiconductors, Non-Crystalline Films, Glass-Ceramics and Glassy Composites,2001(2/3):159-164. |
| [25] | 赵峰,尹玉姬,姚康德,郭刚,王宝利,张镜宇,章明放.壳聚糖-明胶网络/羟基磷灰石复合材料支架的研究--成骨细胞培养[J].中国修复重建外科杂志,2002(02):130-133. |
| [26] | 刘春丽,刘新,徐勇忠.骨基质明胶和壳聚糖复合修复下颌骨缺损的实验研究[J].口腔医学纵横,2001(02):119-121. |
| [27] | Tan W;Krishnaraj R;Desai T A.Influence of chitosan on cell biability and proliferation in three dimensional collagen gels[A].,2000:1509. |
| [28] | Kleinman T E;Gazit Z;Gazit D et al.Synthesis and biodegradation of arabinogalactan sponges prepared by redctive amination[J].Biomaterials,2002,23:4621. |
| [29] | Mazzarelli R A A;Biagini G;Mattioli B M et al.Osteoinduction by chitosan-complexed BMP: morpho-strucural responses in an osteoporotic model[J].Journal of Bioactive and Compatible Polymers,1997,12(04):321. |
| [30] | Park YJ.;Lee JY.;Seol YJ.;Chung CP.;Lee SJ.;Lee YM. .Controlled release of platelet-derived growth factor-BB from chondroitin sulfate-chitosan sponge for guided bone regeneration[J].Journal of Controlled Release: Official Journal of the Controlled Release Society,2000(2/3):385-394. |
| [31] | Park YJ;Lee YM;Park SN;Sheen SY;Chung CP;Lee SJ .Platelet derived growth factor releasing chitosan sponge for periodontal bone regeneration.[J].Biomaterials,2000(2):153-159. |
| [32] | Lee JY.;Nam SH.;Im SY.;Park YJ.;Lee YM.;Seol YJ.;Chung CP.;Lee SJ. .Enhanced bone formation by controlled growth factor delivery from chitosan-based biomaterials[J].Journal of Controlled Release: Official Journal of the Controlled Release Society,2002(1/3):187-197. |
| [33] | Lu JX;Prudhommeaux F;Meunier A;Sedel L;Guillemin G .Effects of chitosan on rat knee cartilages.[J].Biomaterials,1999(20):1937-1944. |
| [34] | Chenite A iosyntech.com;Chaput C;Wang D;Combes C;Buschmann MD;Hoemann CD;Leroux JC;Atkinson BL;Binette F;Selmani A .Novel injectable neutral solutions of chitosan form biodegradable gels in situ.[J].Biomaterials,2000(21):2155-2161. |
| [35] | Sechriest V F;Shuler F;Mian Y J et al.GAG-augmented polysaccharide membrane stabilizes differentiated phenotype of primary chondrocytes in monolayer[J].Transactions of the Orthopedic Research Society,1999,24:723. |
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