采用原位法和液相化学还原法制备了Ag/低分子量壳聚糖(LMWC)和Ag/LMWC-聚吡咯(PPy)复合胶乳,分析了各种工艺条件对复合胶乳中纳米Ag粒子粒径及粒度分布的影响规律,并确定了复合胶乳较适宜的合成条件.采用UV-Vis、TEM、FTIR及XRD对复合胶乳的组成和纳米Ag的形态进行了表征.结果显示:Ag/LMWC和Ag/LMWC-PPy复合胶乳中的纳米Ag晶体为面心立方结构,平均粒径约为10～20 nm.抗菌测试结果表明:LMWC(黏均分子量Mη=4.3×105)的抗菌效果优于未降解的原始壳聚糖(CS),由于纳米Ag的引入,Ag/LMWC和Ag/LMWC-PPy复合胶乳对大肠杆菌和金黄色葡萄球菌与单一的LMWC相比均具有较高的抑菌活性.
参考文献
| [1] | Lu L;Kobayashi A;Tawa K.Silver nanoplates with special shapes:Controlled synthesis and their surface plasmon resonance and surface enhanced Raman scattering properties[J].Chemistry of Materials,200618(20):4894-4901. |
| [2] | Jiang H Q;Manolache S;Wong A C.Plasma enhanced deposition of silver nanoparticles onto polymer and metal surfaces for the generation of antimicrobial characteristics[J].Journal of Applied Polymer Science,200493(03):1411-1422. |
| [3] | Alta V;Bechert T;Steinrucke P.Aninvitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement[J].Biomaterials,200425(18):4383-4391. |
| [4] | BaiS;GuoZH;LiuW.Resolution of (±)-menthol by immobilized candida rugosa lipase on superparamagnetic nanoparticles[J].Food Chemistry,200696(01):1-7. |
| [5] | 王明波;冯庆玲.乳酸-乙醇酸共聚物/壳聚糖复式微球缓释蛋白[J].复合材料学报,201128(05):20-26. |
| [6] | Tang H;Zhang P;Kieft T L.Antibacterial action of a novel functionalized chitosan-arginine against Gram-negative bacteria[J].Acta Biomaterialia,20016(07):2562-2571. |
| [7] | 安静;罗青枝;李雪艳.银/壳聚糖-g-甲基丙烯酸甲酯复合物的制备与抗菌性能[J].复合材料学报,201128(03):127-134. |
| [8] | Yoon H J;MoonME;Park H S.Effects ofchitosan oligosaccharide (COS) on the glycerol-induced acute renal failure in vitro and in vivo[electronic resource][J].Food and Chemical Toxicology,200846(02):710-716. |
| [9] | Chien P J;Sheu F;Huang W T.Effect of molecular weight of chitosans on their antioxidative activities in apple juice[J].Food Chemistry,2007102(04):1192-1198. |
| [10] | Kittur F S;Vishu K;Tharanathan R N.Low molecular weight chitosans-preparation by deploymerization with Aspergillus niger pectinase,and characterization[J].Carbohydrate Research,2003338(12):1283-1290. |
| [11] | Amoozgar Z;Park J Y;Lin Q N.Low molecularweight chitosan as a pH-sensitive stealth coation for tumorspecific drug delivery[J].Molecular Pharmaceutics,20129(05):1262-1270. |
| [12] | Sayas-Barberá E;Quesada J;Sánchez-Zapata E.Effect of the molecular weight and concentration of chitosan in pork model burgers[J].Meat Science,201188(04):740-749. |
| [13] | Zhang J L;Zhang W;Mamadouba B.A comparative study on hypolipidemic activities of high and low molecular weight chitosan in rats[J].International Journal of Biological Macromolecules,201251(04):504-508. |
| [14] | Bo(z)ani(c) D K;Dimitrijevi(c)-Brankovi(c) S;Bibi(c) N.Silver nanoparticles encapsulated in glycogen biopolymer:Morphology,optical and antimicrobial properties[J].Carbohydrate Polymers,201183(02):883-890. |
| [15] | Ali S W;Rajendran S;Joshi M.Synthesis and characterization of chitosan and silver loaded chitosan nanoparticles for bioactive polyester[J].Carbohydrate Polymers,201183(02):438-446. |
| [16] | Madhumathi K;Sudheesh Kumar P T;Abhilash S.Development of novel chitin/nanosilver composite scaffolds for wound dressing applications[J].Journal of Materials Science:Materials in Medicine,201021(02):807-813. |
| [17] | Ong S Y;Wu J;Moochhala S M.Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties[J].Biomaterials,200829(32):4323-4332. |
| [18] | Sekaran S;Sricharan N;Soumitri P.Preparation,characterization and antimicrobial activity of a bio-composite scaffold containing chitosan/nano-hydroxyapatite/nano-silver for bone tissue engineering[J].International Journal of Biological Macromolecules,201149(02):188-193. |
| [19] | Donia A M;Atia A A;Elwakeel K Z.Recovery of gold (Ⅲ) and silver (Ⅰ) on a chemically modified chitosan with magnetic properties[J].Hydrometallurgy,200787(3-4):197-206. |
| [20] | Yoksan R;Chirachanchai S.Silver nanoparticles dispersing in chitosan solution:Preparation by ray irradiation and their antimicrobial activities[J].Materials Chemisty and Physics,2009115(01):296-302. |
| [21] | Twu Y K;Chen Y W;Shih C M.Preparation of silver nano particles using chitosan suspensions[J].Powder Technology,2008185(03):251-257. |
| [22] | Chen S P;Wu G Z;Zeng H Y.Preparation of high antimi crobial activity thiourea chitosan-Ag+ complex[J].Carbohydrate Polymers,200560(01):33-38. |
| [23] | Sanpui P;Murugadoss A;Durga Prasad P V.The antibacterial properties of a novel chitosan-Ag-nanoparticle composite[J].International Journal of Food Microbiology,2008124(02):142-146. |
| [24] | Hamal D B;Klabunde K J.Synthesis,characterization,and visible light activity of new nanoparticle photocatalysts based on silver,carbon,and sulfur-doped TiO2[J].Journal of Colloid and Interface Science,2007311(02):514-522. |
| [25] | Das S;Das M P;Das J.Fabrication of porous chitosan/silver nanocomposite film and its bactericidal efficacy against multidrug resistant (MDR) clinical isolates[J].Journal of Pharmacy Research,20136(01):11-15. |
| [26] | Boiani(c) D K;Trandafilovi(c) L V;Luyt A S.‘Green’ synthesis and optical properties of silver-chitosan complexesand nanocomposites[J].Reactive & Functional Polymers,201070(11):869-873. |
| [27] | Vimala K;Mohan Y M;Sivudu K S.Fabrication of porous chitosan films impregnated with silver nanoparticles:A facile approach for superior antibacterial application[J].Colloids and Surfaces B:Biointerfaces,201076(01):248-258. |
| [28] | Boufi S;Vilar M R;Ferraria A M.In situ photochemical generation of silver and gold nanoparticles on chitosan[J].Colloids and Surfaces A:Physicochemical and Engineering Aspects,2013439:151-158. |
| [29] | Pishbin F;Mouri(n)o V;Gilchrist J B.Single-step electrochemical deposition of antimicrobial orthopaedic coatings based on a bioactive glass/chitosan/nano-silver composite system[J].Acta Biomaterialia,20139(07):7469-7479. |
| [30] | 吴刚.材料结构表征及应用[M].北京:化学工艺出版社,2002:277. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%