基因兴奋剂检测的现状与策略

色谱 , 2008, 26(4): 402-407.

基因兴奋剂检测的现状与策略

何坚刚 ^1, , 刘震 ^2, , 刘晶 ^3, , 窦鹏 ^4, , 陈洪渊 ^5,

1.南京大学化学化工学院,教育部生命分析化学重点实验室,江苏,南京,210093

2.南京大学化学化工学院,教育部生命分析化学重点实验室,江苏,南京,210093

3.南京大学化学化工学院,教育部生命分析化学重点实验室,江苏,南京,210093

4.南京大学化学化工学院,教育部生命分析化学重点实验室,江苏,南京,210093

5.南京大学化学化工学院,教育部生命分析化学重点实验室,江苏,南京,210093

基金项目: 国家自然科学基金科技奥运重点项目(20635002) 国家自然科学基金面上项目(20675038)

关键词：基因兴奋剂 , 重组蛋白 , 检测 , 综述

Advances and strategies in gene doping detection

本文综述了基因兴奋剂检测的现状和反基因兴奋剂的策略.归纳了可能被运动员滥用的基因兴奋剂,分析了由这些基因表达的促红细胞生成素(EPO)、人生长激素(hGH)等蛋白的检测进展,讨论了未来检测基因兴奋剂的可能策略.

参考文献

[1]	World Anti-doping Agency.The 2008 prohibited list.(2007-09-22).http:/ /www.wada-ama.org/rtecontent/document/2008_List_En.pdf
[2]	Azzazy H M E,Mansour M M H.Analyst,2007,132:951
[3]	Svensson E C,Black H B,Dugger D L,et al.Hum Gene Ther,1997,8:1797
[4]	Zhou S,Murphy J E,Escobedo J A,et al.Gene Ther,1998,5:665
[5]	Chenuaud P,Larchet T,Rabinowitz J E,et al.Blood,2004,103:3303
[6]	Sebestyen M G,Hegge J O,Noble M A,et al.Hum Gene Ther,2007,18:269
[7]	Lee S,Barton E R,Sweeney H L,et al.J Appl Physiol,2004,96:1097
[8]	de Francesco L.Nat Biotechnol,2004,22:1069
[9]	Voutetakis A,Bossis I,Kok M R,et al.J Endocrinol,2005,185:363
[10]	Wang Y X,Zhang C L,Yu R T,et al.PLoS Biol,2004,2:e294
[11]	Whittemore L A,Song K,Li X,et al.Biochem Biophys Res Commun,2003,300:965
[12]	Takeuchi M,Kobata A.Glycobiology,1991,1:337
[13]	Mario T,Wilhelm S.Current Proteomics,2005,2:191
[14]	Barton-Davis E R,Shoturma D I,Musaro A,et al.Proc Natl Acad Sci USA,1998,95:15603
[15]	Lippi G,Guidi G C.Br J Sports Med,2004,38:641
[16]	Rankinen T,Perusse L,Rauramaa R.Med Sci Sports Exerc,2002,34:1219
[17]	Lasne F,de Ceaurriz J.Nature,2000,405:635
[18]	Frutos M,Cifuentes A,Diez-Masa J C.Electrophoresis,2003,24:678
[19]	Franke W W,Heid H.Clin Chim Acta,2006,373:189
[20]	Dou P,Liu Z,He J G,et al.J Chromatogr A,2008,1190:372
[21]	Parisotto R,Ashenden M J,Gore C J,et al.Haematologica,2003,88:931
[22]	Parisotto R,Gore C J,Emslie K R,et al.Haematologica,2000,85:564
[23]	Kazlauskas R,Howe C,Trout G.Clin J Sport Med,2002,12:229
[24]	Thomer M O,Smith R G.Human growth hormone:research and clinical practice.Totowa:Humana Press,2000
[25]	Bidlingmaier M,Wu Z,Strasburger C J.J Endocrinol Invest,2003,26:924
[26]	Saugy M,Robinson N,Saudan C,et al.Br J Sports Med,2006,40:35
[27]	McHugh C M,Park R T,Sonksen P H,et al.Clin Chem,2005,51:1587
[28]	Kniess A,Ziegler E,Kratzsch J,et al.Anal Bioanal Chem,2003,376:696
[29]	Palo E F,Gatti R,Lancerin F,et al.Clin Chim Acta,2001,305:1
[30]	Juul A,Dalgaard P,Blum W F,et al.J Clin Endocrinol Metab,1995,80:2534
[31]	Kraemer W J,Aguilera B A,Terada M,et al.J Appl Physiol,1995,79:1310
[32]	Sartorio A,Agosti F,Marazzi N,et al.Clin Endocrinol,2004,61:487
[33]	Lasne F,Martin L,de Ceaurriz J,et al.Mol Ther,2004,10:409
[34]	Hassan M E A,Mai M H M,Robert H C.Clin Biochem,2005,38:959
[35]	Play True:An Official Publication of the World Anti-Doping Agency,Issue 1-2005

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基因兴奋剂检测的现状与策略

Advances and strategies in gene doping detection

参考文献