以0.3 mol/L草酸为电解液,利用磁控溅射镀铝与阳极氧化相结合的方法在医用316L不锈钢表面制备了亚微米至微米尺度的载药微孔.利用扫描电镜和X射线能谱对微孔表面形貌和元素分布进行观察和分析;并运用电化学极化曲线法研究了多孔316L不锈钢在生理盐水溶液中的腐蚀行为.研究结果表明:微孔的尺寸随着氧化电压的增加和氧化时间的延长而增大;且316L不锈钢的耐腐蚀性提高.
参考文献
| [1] | 柯永胜.药物洗脱支架的临床研究进展[J].国际心血管病杂志,2006(05):333-337. |
| [2] | Finn AV;Kolodgie FD;Harnek J;Guerrero LJ;Acampado E;Tefera K;Skorija K;Weber DK;Gold HK;Virmani R .Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents.[J].Circulation,2005(2):270-278. |
| [3] | Virmani R;Guaglimui G;Farb A et al.Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent:should we be cautious?[J].Circulation,2004,109(06):701-705. |
| [4] | Wieneke H;Dirsch O;Sawitowski T;Gu YL;Brauer H;Dahmen U;Fischer A;Wnendt S;Erbel R .Synergistic effects of a novel nanoporous stent coating and tacrolimus on intima proliferation in rabbits.[J].Catheterization and cardiovascular interventions: Official journal of the Society for Cardiac Angiography & Interventions,2003(3):399-407. |
| [5] | Serruys P W;Sianos G;Abizaid A et al.The effect of variable dose and release kinetics on neointimal hyperplasia using a novel paclitaxel-eluting stent platform:the paclitaxel in-stent controlled elution study (PISCES)[J].J.Am.Coll.Cardiol,2005,46(02):253-260. |
| [6] | Wessely R;Hausleiter J;Michaelis C et al.Inhibition of neointima formation by a novel drug-eluting stent system that alows for dose-adjustable,multiple,and on-site stent coating[J].Arter.Thromb.Vasc.Biol,2005,25(04):748-753. |
| [7] | 王玉江,马欣新,唐光泽,张丽芳.偏压对316L不锈钢上磁控溅射镀铝膜结构的影响研究[C].第7届全国表面工程学术会议暨第二届表面工程青年学术论坛论文集,2008:246-248. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%