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利用扫描电镜、X衍射仪以及红外漫反射仪,并通过对生物活性玻璃/聚乳酸组织工程支架在模拟体液(SBF)中失重率及模拟体液pH值的变化的检测,系统研究了生物活性玻璃/聚乳酸组织工程支架在SBF中的降解和矿化性能。结果发现:随着含有生物活性玻璃的聚乳酸支架在SBF溶液中浸泡时间的增长,SBF的pH值不断下降;含有生物活性玻璃的聚乳酸支架的质量不断下降。XRD、FTIR谱图和SEM图像表明:在SBF中浸泡一定时间后,有无定型的或结晶不完善的磷灰石在含有生物活性玻璃的聚乳酸支架的表面沉积形成。

The degradable performance and bio-mineralization function of bioglass/poly(lactic acid) tissue engineering scaffolds were systematically studied in the simulated body fluid(SBF) by measuring pH value of SBF,the loss mass rate of the scaffolds and analyzing SEM pictures,XRD and FTIR spectra of scaffolds' surface.It was found that in SBF,the pH value of SBF with bioglass/poly(lactic acid) tissue engineering scaffolds and the mass of bioglass/poly(lactic acid) scaffolds decreases with the prolongation of time.SEM pictures and XRD,FTIR spectra showed that there appears the deposition of carbonate hydroxyl apatite on the surface of the bioglass/poly(lactic acid) tissue engineering scaffolds.The result shows that the bioglass/poly(lactic acid) tissue engineering scaffolds have good bio-mineralization function.

参考文献

[1] Balamurugan A, Balossier G, Kannan S, et al. Development and in vitro characterization of sol-gel derived CaO-P2O5-SiO2-ZnO bioglass [J]. Acta Biomaterialia, 2007, 3(2): 255-262.
[2] Liu Jianli, Miao Xigeng. Sol-gel derived bioglass as a coating material for porous alumina scaffolds [J]. Ceramics International, 2004, 30(7): 1781-1785.
[3] ElBatal H A, Azooz M A, Khalil E M A, et al. Characterization of some bioglass-ceramics [J]. Materials Chemistry and Physics, 2003, 80(3): 599-609.
[4] Chan C, Thompson I, Robinson P, et al. Evaluation of bioglass/dextran composite as a bone graft substitute [J]. International Journal of Oral and Maxillofacial Surgery, 2002, 31(1): 73-77.
[5] Qian Junmin, Kang Yahong, Wei Zilin, et al. Fabrication and characterization of biomorphic 45S5 bioglass scaffold from sugarcane [J]. Materials Science and Engineering C, 2009, 29(4): 1361-1364.
[6] Lee Bor-Shiunn, Chang Chun-Wei, Chen Weng-Pin, et al. In vitro study of dentin hypersensitivity treated by Nd∶YAP laser and bioglass [J]. Dental Materials, 2005, 21(6): 511-519.
[7] 杜瑞林, 倪似愚, 常江, 等. 含Zn生物玻璃、玻璃陶瓷与聚酯复合骨组织工程支架的制备及性能 [J]. 复合材料学报, 2008, 25(6): 123-129.
[8] Kokubo T, Kushitani H, Sakka S, et al. Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W [J]. J Biomed Mater Res, 1990, 24(7): 721-734.
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