采用浸渍涂敷-烧结法首次在医用三维钛网表面制备出双生物陶瓷涂层,利用X射线衍射、场发射扫描电子显微镜对HA-BG/BG/Ti复合材料进行了微观表征,拉伸法测量了Ti基体与BG涂层的结合强度,模拟人体体液(SBF)评价复合材料的生物相容性.研究表明:该双生物陶瓷涂层的内层为生物玻璃(BG)涂层,外层为多孔结构的羟基磷灰石-生物玻璃(HA-BG)复合涂层.Ti基体被致密的BG涂层包覆,由于在BG/Ti界面发生化学反应,界面的结合强度提高,平均结合强度达27 MPa.生物相容性实验表明,HA-BG/BG/Ti复合材料表面会被一层整齐、致密的HA覆盖,具有良好的生物相容性.
参考文献
| [1] | L.C. Zhang;D. Klemm;J. Eckert .Manufacture by selective laser melting and mechanical behavior of a biomedical Ti-24Nb-4Zr-8Sn alloy[J].Scripta materialia,2011(1):21-24. |
| [2] | Ti based biomaterials, the ultimate choice for orthopaedic implants - A review[J].Progress in materials science,2009(3):397. |
| [3] | COOK S D;THOMAS K A;DELTON E J et al.Hydroxylapatite coating of porous implants improves bone ingrowth and interface attachment stregnth[J].Journal of Biomedical Matererials Research,1992,26:989-1001. |
| [4] | 高虎,林倩,杨林.纳米HAP粉末的制备技术及其研究进展[J].贵州化工,2011(01):30-33,45. |
| [5] | Zavgorodniy AV;Borrero Lopez O;Hoffman M;LeGeros RZ;Rohanizadeh R .Mechanical stability of two-step chemically deposited hydroxyapatite coating on Ti substrate: effects of various surface pretreatments.[J].Journal of biomedical materials research, Part B. Applied biomaterials,2011(1):58-69. |
| [6] | LIN C-C;CHEN S-F;LEUNG K S et al.Effects of CaO/P2O5 ration on the structure and elastic properties of SiO2-CaO-Na2O-P2O5 bioglasses[J].Journal of Materials Science:Materials in Medicine,2012,23(02):245-258. |
| [7] | Guocheng Wang;Zufu Lu;Xuanyong Liu .Nanostructured glass-ceramic coatings for orthopaedic applications[J].Journal of the Royal Society Interface,2011(61):1192-1203. |
| [8] | HENCH L .Bioceramics:from concept to clinic[J].Journal of the American Ceramic Society,1991,74(07):1487-1510. |
| [9] | XIU Z M;LIU Y;LI J G et al.Fabrication and properties of hydroxyapatite-Ti network composites[J].Advance Materials Research,2008,41:41-48. |
| [10] | Ning CQ.;Zhou Y. .On the microstructure of biocomposites sintered from Ti, HA and bioactive glass[J].Biomaterials,2004(17):3379-3387. |
| [11] | YI D;WU C;MA X et al.Preparation and in vitro evaluation of plasma-sparyed bioactive akermanite coatings[J].Biomedical Materials,2012,7(06):1-10. |
| [12] | Demnati, I.;Parco, M.;Grossin, D.;Fagoaga, I.;Drouet, C.;Barykin, G.;Combes, C.;Braceras, I.;Goncalves, S.;Rey, C. .Hydroxyapatite coating on titanium by a low energy plasma spraying mini-gun[J].Surface & Coatings Technology,2012(8/9):2346-2353. |
| [13] | Braem, A.;Neirinck, B.;Schrooten, J.;Van Der Biest, O.;Vleugels, J. .Biofunctionalization of porous titanium coatings through sol-gel impregnation with a bioactive glass-ceramic[J].Materials science & engineering, C. Biomimetic and supramolecular systems,2012(8):2292-2298. |
| [14] | Christopher J. Tredwin;George Georgiou;Hae-Won Kim;Jonathan C. Knoiules .Hydroxyapatite, fluor-hydroxyapatite and fluorapatite produced via the sol-gel method: Bonding to titanium and scanning electron microscopy[J].Dental materials,2013(5):521-529. |
| [15] | YI W;HU X;SUN X.Processing and properties of bioceramic coatings onto 3D Ti-mesh by dipcasting method[J].International Journal of Applied Ceramic Technology,2013:1-9. |
| [16] | Bora Mavis;A. Cuneyt Tas .Dip coating of calcium hydroxyapatite on Ti-6Al-4V substrates[J].Journal of the American Ceramic Society,2000(4):989-991. |
| [17] | WILLIAM J;CALLISTER D.Materials science and engineering an introduction[M].Salt Lake City:The Univeristy of Utah,1999:804-806. |
| [18] | Kokubo T;Takadama H .How useful is SBF in predicting in vivo bone bioactivity?[J].Biomaterials,2006(15):2907-2915. |
| [19] | 杨班权,陈光南,张坤,罗耕星,肖京华.涂层/基体材料界面结合强度测量方法的现状与展望[J].力学进展,2007(01):67-79. |
| [20] | Yi, W.;Hu, X.;Ichim, P.;Sun, X..Processing and properties of pressable ceramic with non-uniform reinforcement for selective-toughening[J].Materials Science & Engineering, A. Structural Materials: Properties, Misrostructure and Processing,2012:543-549. |
| [21] | DONALD I W .Preparation,properties and chemistry of glass-and glass-ceramic-to-metal seals and coatings[J].Journal of Materials Science,1993,28:2841-2886. |
| [22] | Mingli Shen;Shenglong Zhu;Minghui Chen .The Oxidation and Oxygen Permeation Resistance of Quartz Particle- Reinforced Aluminosilicate Glass Coating on Titanium Alloy[J].Journal of the American Ceramic Society,2011(8):2436-2441. |
| [23] | Huang J;Best SM;Bonfield .Development and characterization of titanium-containing hydroxyapatite for medical applications.[J].Acta biomaterialia,2010(1):241-249. |
| [24] | DEMNATI I;GROSSIN D;COMBES C et al.A comparative physico-chemical strudy of chlorapatite and hydroxyapatite:from powders to plasma sparyed thin coatings[J].Biomedical Materials,2012,7(05):1-10. |
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