RGD(Arg-G1y-Asp)短肽序列是一种细胞粘附肽,能被细胞膜上的整合素识别,参与细胞与基质间的粘附.为改善合成生物材料缺乏细胞识别信号的缺点,可将含RGD序列肽经本体或表面修饰引入材料,使材料具有良好的细胞亲和性.综述了采用含RGD肽对各种合成生物材料进行仿生修饰的研究进展.
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