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采用硅烷偶联剂对生物活性玻璃(BG)进行表面修饰以改善其与高分子的亲和性.通过溶胶凝胶法制得BG,将氨丙基三乙氧基硅烷(APTES)键连到BG表面,采用FTIR、TG、激光粒度仪等对修饰前后的BG进行表征,并通过细胞实验对材料的细胞相容性进行初步研究.结果表明,修饰后BG的FTIR图谱上出现归属于C-H的伸缩振动吸收峰,在DTG曲线上观察到明显的有机基团燃烧失重峰,表明APTES接枝到生物玻璃表面;而MC-3T3细胞增殖测定和SEM结果显示经表面修饰后的BG更有利于细胞的生长增殖.

参考文献

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