欢迎登录材料期刊网

材料期刊网

高级检索

A new kind of tissue engineering scaffold materials of nano-apatite ( NA ) and polyamide6( PA6) biocomposite was prepared by means of the co-solution method. The NA crystals uniformly distribute in the composite with a size of 10- 30 nm in diameter by 50- 90 nm in length. The NA/ PA6 composite has good homogeneity and high NA content, and excellent mechanical properties close to those of natural bone. The porous 3-D scaffold has not only macropores, but also micropores on the walls of macropores with porosity of about 80% and the size of pore diameter of about 300μm made by injection foam. The biocomposite can be used for bone repair and as scaffolds in tissue engineering.

参考文献

[1] Yong Zhang;Miqin Zhang .Synthesis and Characterization of Macroporous Chitosan/Calcium Phosphate Composite Scaffolds for Tissue Engineering[J].Journal of Biomedical Materials Research Part A,2001,26:304-312.
[2] Hardy DGR;Frayssinet P .Osteointegration of Hydroxyapatite Coated Stems of Femoral Prostheses[J].European Journal of Orthopaedic Surgery and Traumatology,1999,9:75-81.
[3] Cleries L.;Morenza JL.;Fernandez-Pradas JM. .Behavior in simulated body fluid of calcium phosphate coatings obtained by laser ablation[J].Biomaterials,2000(18):1861-1865.
[4] L Di Silvio;M Dalby;W Bonfield .In vivo Response of Osteoblasts to Hydroxapatite-reinforced Polyethylene Composites[J].Journal of Materials Science:Materials in Medicine,1998,9:845-848.
[5] C Du;F Z Cui;Feng QL;Zhu XD de Groot K .Tissue Reponse to Nano-hydroxyapatite/collagen Composite Implants in Marrow Cavity[J].Journal of Biomedical Materials Research Part A,1998,42:540-548.
[6] Zhang R Y;Ma P X .Porous Poly (L-lactic acid)/Apatite Composites Created by Biomimetic Process[J].Journal of Biomedical Materials Research Part A,1999,45:285-293.
[7] Wei Jie;Li Yubao .Processing and Properties of Nano Apatitepolyamide Biocomposite[J].Journal of Materials Science Letters,2005,40(03):793-796.
[8] Jie Wei,Yubao LI,Yi ZUO,Xueling PENG,Li ZHANG.Development of Biomimetic Needle-like Apatite Nanocrystals by a Simple New Method[J].材料科学技术学报(英文版),2004(06):665-667.
[9] Wei J.;Li YB.;Chen WQ.;Zuo Y. .A study on nano-composite of hydroxyapatite and polyamide[J].Journal of Materials Science,2003(15):3303-3306.
[10] Xuejiang Wang;Yubao Li;Jie Wei .Development of Biomimetic Nano-hydroxylapatite/Poly (hexamethylene adipamide)Composites[J].Biomaterials,2002,23:4787-91.
[11] Bonfield W;Grynpas M D;Tully AE;Bowman J Abram J .Hydroxyapatite Reinforced Polyethylene Mechanically Compatible Implant Material for Bone Replacement[J].BIOMATERIALS,1981,2:185-6.
[12] Jie W.;Li Y. .Tissue engineering scaffold material of nano-apatite crystals and polyamide composite[J].European Polymer Journal,2004(3):509-515.
上一张 下一张
上一张 下一张
计量
  • 下载量()
  • 访问量()
文章评分
  • 您的评分:
  • 1
    0%
  • 2
    0%
  • 3
    0%
  • 4
    0%
  • 5
    0%