用苯乙烯封端的聚乙二醇(St-PEG)大单体与苯乙烯(St)进行接枝共聚,将得到的双亲性接枝共聚物(PEG-g-PSt)逐步滴加到各种比例的甲醇/水的混合溶剂中,通过该聚合物在混合溶剂中的自组装,制得了PEG-g-PSt微球.用透射电子显微镜(TEM)和激光光散射(LLS)对微球的形态和粒径进行了表征.实验结果表明,改变接枝液组成、接枝液浓度、滴加速度以及混合溶剂组成等反应条件可有效地控制所得微球的粒径及其分布.
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