以羟基磷灰石-壳聚糖(HA-CS)为基体,碳纤维(C_((f)))为增强相,采用原位杂化法制备短切碳纤维增强HA-CS基生物复合材料.对所制备的可吸收C_((f))/HA-CS复合骨折内固定材料的吸湿膨胀及生物活性进行评价.研究羟基磷灰石含量对复合材料吸水性的影响以及复合材料在模拟体液中浸泡不同时间后的质量变化和表面羟基磷灰石的微晶仿生生长情况.采用X射线衍射仪(XRD)和扫描电子显微镜(SEM)对模拟体液浸泡后材料的结构和形貌进行表征.结果表明:复合材料中羟基磷灰石的含量与吸水率成反比,通过控制HA的含量可以控制复合材料的膨胀度;复合材料在模拟体液浸泡的过程中,随着浸泡时间的延长,复合材料的质量呈现先减少后增加的变化规律,复合材料具有很好的生物活性,能诱导羟基磷灰石微晶的沉积.
Polyacrylonitrile-based short carbon fiber reinforced hydroxyapatite-chitosan (HA-CS) composites (C_((f))/CS-HA) were prepared by in-situ hybridization process using HA-CS as matrix and C_((f)) as reinforcing phase. The hygroscopicity expansion and bioactivities of the absorbable C_((f))/HA-CS composite rods used as internal fixation materials of bone fractures were evaluated. The influence of HA content on the water absorptivity of the composites was investigated. The mass change and formation of HA of the composites immersed in the simulated body fluid for different time were also studied. The surface phase compositions and surface morphologies of the immersed composites were characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM). Results show that there is an inversely-proportional relationship between the water absorptivity of the composites and HA content. The degree of expansion of the composites can be controlled by adjusting the HA content. The mass of the composites first decreases and then increases with the increase of soaking time in SBF solution. After soaking in SBF solution, HA crystallites are found to be deposited on the surface of C_((f))/HA-CS composites, which inferred the good bioactivity of the composites.
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