分别处于阴阳离子中具有两种碱性位点的离子液体催化剂1-(2-哌啶基-乙基)-3-甲基咪唑吗啉乙基磺酸盐([Pemim]-Mes)在Knoevenagel缩合反应中表现出明显的协同促进催化作用. 该催化剂在非酸性条件下循环使用10次以后仍保持良好的活性和稳定性,并普遍适用于芳香醛类底物的缩合反应. 根据实验结果,提出了紧密结合的碱性阴阳离子对协同催化Knoevenagel缩合的反应机理.
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