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在软骨组织修复与再生中,纳米纤维为细胞提供了良好的微环境,是软骨渗复的一种理想材料.首先介绍了纳米纤维的制备方法,包括相分离、电纺和自组装,特别针对新结构和新性能的纳米纤维的研究进展展开了论述.最后介绍了软骨细胞、干细胞与纳米纤维的复合以及生物活性因子如生长因子、基因对软骨再生的促进作用.

参考文献

[1] Bonzani IC;George JH;Stevens MM .Novel materials for bone and cartilage regeneration[J].Current opinion in chemical biology,2006(6):568-575.
[2] Elisseeff J .Injectable cartilage tissue engineering[J].Expert Opinion on Biological Therapy,2004,4(12):1849.
[3] Chung C;Burdick JA .Engineering cartilage tissue.[J].Advanced drug delivery reviews,2008(2):243-262.
[4] Stevens M M;George J H .Exploring and engineering the cell surface interface[J].Science,2005,310:1135.
[5] Cao H;Liu T;Chew SY .The application of nanofibrous scaffolds in neural tissue engineering.[J].Advanced drug delivery reviews,2009(12):1055-1064.
[6] Ma PX .Biomimetic materials for tissue engineering.[J].Advanced drug delivery reviews,2008(2):184-198.
[7] Ma P X;Zhang R .Synthetic nano-scale fibrous extracellular matrix[J].Journal of Biomedical Materials Research,1999,46(01):60.
[8] Yang F.;Murugan R.;Ramakrishna S.;Wang X.;Ma YX.;Wang S. .Fabrication of nano-structured porous PLLA scaffold intended for nerve tissue engineering[J].Biomaterials,2004(10):1891-1900.
[9] Chen VJ;Smith LA;Ma PX .Bone regeneration on computer-designed nano-fibrous scaffolds.[J].Biomaterials,2006(21):3973-3979.
[10] Barnes CP;Sell SA;Boland ED;Simpson DG;Bowlin GL .Nanofiber technology: Designing the next generation of tissue engineering scaffolds.[J].Advanced drug delivery reviews,2007(14):1413-1433.
[11] Zhang R.;Ma P.X. .Synthetic nano-fibrillar extracellular matrices with predesigned macroporous architectures[J].Journal of biomedical materials research, Part B. Applied biomaterials,2000(2):430-438.
[12] Wei G;Ma PX .Macroporous and nanofibrous polymer scaffolds and polymer/bone-like apatite composite scaffolds generated by sugar spheres.[J].Journal of biomedical materials research, Part A,2006(2):306-315.
[13] Piskin E;Bolgen N et al.Electrospun matrices made of poly(alpha-hydroxy acids)for medical use[J].Nanomedicine(Lond),2007,2(04):441.
[14] Lim SH;Mao HQ .Electrospun scaffolds for stem cell engineering.[J].Advanced drug delivery reviews,2009(12):1084-1096.
[15] Soema Agarwa;Andreas Greiner et al.Progress in the field of electrospinning for tissue engineering applications[J].Advanced Materials,2009,21:3343.
[16] Maciej Skotak;Alexei P. Leonov;Gustavo Larsen .Biocompatible and Biodegradable Ultrafine Fibrillar Scaffold Materials for Tissue Engineering by Facile Grafting of L-Lactide onto Chitosan[J].Biomacromolecules,2008(7):1902-1908.
[17] Madhab P B;Shanta R B et al.Poly(-caprolactone)grafted dextran biodegradable electrospun matrix:A novel scaffold for tissue engineering[J].Journal of Applied Polymer Science,2008,108(03):1447.
[18] Matsuda A;Kagata G;Kino R;Tanaka J .Preparation of chitoscan nanofiber tube by electrospinning[J].Journal of nanoscience and nanotechnology,2007(3):852-855.
[19] Y.Z.Zhang;J.Venugopal;Z.-M.Huang;C.T.Lim;S.Ramakrishna .Crosslinking of the electrospun gelatin nanofibers[J].Polymer: The International Journal for the Science and Technology of Polymers,2006(8):2911-2917.
[20] Schiffman J D;Schauer C L .One-step eleetrospinning of cross-linked chitosan fibers[J].Biomacromolecules,2007,8(09):12665.
[21] Zaicheng Sun;Eyal Zussman;Alexander L. Yarin;Joachim H. Wendorff;Andreas Greiner .Compound Core-Shell Polymer Nanofibers by Co-Electrospinning[J].Advanced Materials,2003(22):1929-1932.
[22] Y.Z.Zhang;J.Venugopal;Z.-M.Huang;C.T.Lim;S.Ramakrishna .Characterization of the Surface Biocompatibility of the Electrospun PCL-Collagen Nanofibers Using Fibroblasts[J].Biomacromolecules,2005(5):2583-2589.
[23] Zhao P;Jiang H;Pan H;Zhu K;Chen W .Biodegradable fibrous scaffolds composed of gelatin coated poly(epsilon-caprolactone) prepared by coaxial electrospinning.[J].Journal of biomedical materials research, Part A,2007(2):372-382.
[24] Jiang H;Hu Y;Zhao P;Li Y;Zhu K .Modulation of protein release from biodegradable core-shell structured fibers prepared by coaxial electrospinning.[J].Journal of biomedical materials research, Part B. Applied biomaterials,2006(1):50-57.
[25] Ji Y;Ghosh K;Li BQ;Sokolov JC;Clark RAF;Rafailovich MH .Dual-syringe reactive electrospinning of cross-linked hyaluronic acid hydrogel nanofibers for tissue engineering applications[J].Macromolecular bioscience,2006(10):811-817.
[26] Murugan R;Ramakrishna S .Design strategies of tissue engineering scaffolds with controlled fiber orientation.[J].Tissue engineering,2007(8):1845-1866.
[27] Tong HW;Wang M .Electrospinning of aligned biodegradable polymer fibers and composite fibers for tissue engineering applications[J].Journal of nanoscience and nanotechnology,2007(11):3834-3840.
[28] Matthews J A;Wnek G E et al.Electrospinning of collagen nanofibers[J].Biomacromolecules,2002,3(02):232.
[29] Li Dan;Xia Younan et al.Electrospirming of polymeric and ceramic nanofibers as uniaxially aligned arrays[J].Nano Letters,2003,3(08):1167.
[30] Xu CY;Inai R;Kotaki M;Ramakrishna S .Aligned biodegradable nanofibrous structure: a potential scaffold for blood vessel engineering.[J].Biomaterials,2004(5):877-886.
[31] Yang Dongzhi;Zhang Jing et al.Aligned electrospun nanofibers induced by magnetic field[J].Journal of Applied Polymer Science,2008,110:3368.
[32] Dan Li;Yuliang Wang;Younan Xia .Electrospinning Nanofibers as Uniaxially Aligned Arrays and Layer-by-Layer Stacked Films[J].Advanced Materials,2004(4):361-366.
[33] Katta P;Alessandro M;Ramsier RD;Chase GG .Continuous electrospinning of aligned polymer nanofibers onto a wire drum collector[J].Nano letters,2004(11):2215-2218.
[34] Lorenzo M;Doreen H et al.3D fiber-deposited electrospun integrated scaffolds enhance cartilage tissue formation[J].Adv Funet Mater,2008,18:53.
[35] Yang X;Shah JD;Wang H .Nanofiber enabled layer-by-layer approach toward three-dimensional tissue formation.[J].Tissue engineering, Part A,2009(4):945-956.
[36] Whitesides G M;Grzybowski B .Self-assembly at all scales[J].Science,2002,295:2418.
[37] Roemer D;Buescher H H et al.A synthetic enkephalin ana-logne with prolonged parenteral and oral analgesic activity[J].Nature,1977,268:547.
[38] Dario Pasini .Supramotecular self-assembly of fibres[J].Current Opinion in Solid State and Materials Science,2004,8:157.
[39] Liu XY.;Sawant PD.;Tan WB.;Noor IBM.;Pramesti C.;Chen BH. .Creating new supramolecular materials by architecture of three-dimensional nanocrystal fiber networks[J].Journal of the American Chemical Society,2002(50):15055-15063.
[40] Wang R;Liu X Y et al.Real-time observation of fiber network formation in molecular organogel:Supersaturation-dependent microstructure and its related rheological property[J].J Pbys Chem B,2006,110:7275.
[41] Xiang Yang Liu;Prashant D. Sawant .Mechanism of the Formation of Self-Organized Microstructures in Soft Functional Materials[J].Advanced Materials,2002(6):421-426.
[42] Xiao Huang;Pierre Terech;Pierre Terech;Richard G.Weiss .Kinetics of 5a-Cholestan-3beta-yl N-(2-Naphthyl)carbamate/n-Alkane Organogel Formation and Its Influence on the Fibrillar Networks[J].Journal of the American Chemical Society,2005(12):4336-4344.
[43] 胡小红,朱旸
[44] Kisiday J;Jin M;Kurz B;Hung H;Semino C;Zhang S;Grodzinsky AJ .Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: Implications for cartilage tissue repair.[J].Proceedings of the National Academy of Sciences of the United States of America,2002(15):9996-10001.
[45] Kretsinger JK;Haines LA;Ozbas B;Pochan DJ;Schneider JP .Cytocompatibility of self-assembled beta-hairpin peptide hydrogel surfaces.[J].Biomaterials,2005(25):5177-5186.
[46] He Dong;Sergey E.Paramonov;Lorenzo Aulisa .Self-Assembly of Multidomain Peptides:Balancing Molecular Frustration Controls Conformation and Nanostructure[J].Journal of the American Chemical Society,2007(41):12468-12472.
[47] Li WJ;Tuli R;Okafor C;Derfoul A;Danielson KG;Hall DJ;Tuan RS .A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells.[J].Biomaterials,2005(6):599-609.
[48] Xin X;Hussain M et al.Continuing differentiation of human mesenchyrnal stem cells and induced chondrogenic and ostcogenic lineages in electrospun PLGA nanofiber scaffold[J].Biomaterials,2007,28(02):316.
[49] Li WJ;Tuli R;Huang X;Laquerriere P;Tuan RS .Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold.[J].Biomaterials,2005(25):5158-5166.
[50] Sing Yian Chew;Jie Wen;Evelyn K.F.Yim;Kam W.Leong .Sustained Release of Proteins from Electrospun Biodegradable Fibers[J].Biomacromolecules,2005(4):2017-2024.
[51] 李安永;田现书 .谈谈人类疾病的基因治疗[J].生物学通报,1998,33(06):24.
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