近年来手性拆分成为新的研究热点,手性固定相的研究发展异常迅速.立足于国内外手性固定相的研究成果,介绍了手性固定相的分类及其应用,并重点综述了基于酰胺的手性固定相的发展及其制备方法.同时简要介绍了作为手性固定相对不同异构体的识别机理,并对该领域未来的发展方向进行了展望.
参考文献
| [1] | 达世禄;徐伟;董亚琼.手性高效液相色谱固定相[J].化学通报(印刷版),1997(02):33. |
| [2] | 尹国,刘振华,曾姗姗,朱国洪.手性异构体拆分方法的研究进展[J].中国药物化学杂志,2001(01):57-62. |
| [3] | 魏明星,姚金水,王晓东,武光,张希岩,何倩倩.高效液相色谱手性聚合物固定相的研究与进展[J].高分子通报,2006(10):23-28. |
| [4] | 宋雅茹,王德发,杨亦平,吴红,牛丽萍,侯冬岩.酰胺型手性固定相直接拆分克仑特罗对映体[J].色谱,2002(02):118-120. |
| [5] | 宋雅茹,王德发,牛丽萍,胡玉萍,杨亦平,侯冬岩.利用酰胺型手性固定相高效液相色谱法对格列美脲顺反异构体的分离与测定[J].分析化学,2004(04):435-438. |
| [6] | Peters E C;Lcwandowski K;Petro M et al.Chiral electrochromatography with a 'moulded' rigid monolithic capillary column[J].Analysis Communications,1998,35:83. |
| [7] | 翁文,姚碧霞,尤秀丽,曾庆乐.L-酒石酸型手性固定相拆分联萘酚对映体[J].应用化学,2004(08):853-855. |
| [8] | 翁文,林敏,钟艺聪,陈武安,陈慧敏,曾庆乐.L-酒石酸型固定相对映分离氨基酸衍生物[J].分析化学,2004(02):213-216. |
| [9] | 姚碧霞,陈丽雪,陈秀琴,唐丽云,翁文.高效液相色谱测定氨基酸衍生物的对映纯度[J].应用化工,2005(03):174-175. |
| [10] | Chen Z;Hobo T .Chemically L-phenylalaninamide-modified monolithic silica column prepared by a sol-gel process for enantioseparation of dansyl amino acids by ligand exchangecapillary electrochromatography[J].Analytical Chemistry,2001,73:3348. |
| [11] | Krause K;Girod M;Chankvetadze B et al.Enantioseparations in normal-and reversed-phase nano-highper-formance liquid chromatography and capillary electrochromatography usin gpolyacrylamide and polysaccharide derivatives as chiral stationary phases[J].Journal of Chromatography A,1999,837:51. |
| [12] | Huang Junmin;Zhang Peng;Chen Hui et al.Preparation and evaluation of proline-based chiral columns[J].Analytical Chemistry,2005,77:3301. |
| [13] | 王晓东,姚金水,魏明星,武光,罗存.手性识别及氨基酸类手性固定相的研究进展[J].有机化学,2006(07):912-921. |
| [14] | 王云普,李全莲,袁昆.聚苯乙烯负载手性化合物的合成[J].西北师范大学学报（自然科学版）,2005(01):41-42,54. |
| [15] | Takashi Koide;Kyoji Ueno .Enantiomeric separations of cationic and neutral compounds by capillary electrochromatography with monolithic chiral stationary phases of beta-cyclodextrin-bonded negatively charged polyacrylamide gels[J].Journal of Chromatography A,2000,893:177. |
| [16] | Ruderisch A.;Schurig V.;Pfeiffer J. .Synthesis of an enantiomerically pure resorcinarene with pendant L-valine residues and its attachment to a polysiloxane (Chirasil-Calix)[J].Tetrahedron, Asymmetry: The International Journal for Repid Publication on all Aspects of Asymmetry in Orgainc, Inorganic, Organometallic, Physical and Bio-Organic Chemistry,2001(14):2025-2030. |
| [17] | Abe I;Ohtani S .Novel chiral selectors anchored on polydimethylsiloxane as stationary phases for separation of derivatized amino acid enantiomers by capillary gas chromatography[J].Journal of separation science,2006(2):319-324. |
| [18] | Koide T;Ueno K .Enantiomeric separations of primary amino compounds by capillary electrochromatography with monolithic chiral stationary phases of chiral crown etherbonded negatively charged polyacrylamide gels[J].Journal of Chromatography A,2001,909(02):305. |
| [19] | Zhang X Z;Zhang J T;Zhuo R X et al.Synthesis and properties of thermosensitive,crown ether incorporated poly(N-isopropylacrylamide) hydrogel[J].POLYMER,2002,43:4823. |
| [20] | Han X;He L;Zhong Q et al.Synthesis and evaluation of a synthetic polymeric chiral stationary phase for LC based on the N,N'-[(1R,2R)-1,2-Diphenyl-1,2-ethanediyl] bis2-propenamide[J].Armstrong Chromatographia,2006,63:13. |
| [21] | 徐修容;唐琴梅;汪润英 .高效液相色谱手性固定相的研究[J].化学学报,1983,41(03):262. |
| [22] | 马娟娟,王新龙,杨春杰.分子印迹聚合物材料在手性药物分离和药物检测中的应用[J].化工时刊,2004(01):5-8. |
| [23] | 张丽芬.分子印迹技术及其在痕量分析的应用[J].曲靖师范学院学报,2005(03):14-18. |
| [24] | TAKAHIKO MATSUI;TOMO OSAWA;KAZUMI SHIRASAKA .Improved Method of Molecular Imprinting of Cyclodextrin on Silica-gel Surface for the Preparation of Stable Stationary HPLC Phase[J].Journal of Inclusion Phenomena and Macrocyclic Chemistry,2006(1/2):39-44. |
| [25] | 许志刚.分子印迹技术及其在色谱分离中的应用研究[J].琼州大学学报,2006(02):15-17. |
| [26] | 王也,富同义.毛细管电色谱在分离手性化合物中的应用[J].中国药业,2006(08):64-66. |
| [27] | Liu Haiyan;Kyung Ho Row;Yang Gengliang .Monolithic molecularly imprinted columns for chromatographic separation[J].Chromarographia,2005,61:429. |
| [28] | Lin M;Uchiyama K .Enantioseparation of D,L-phenylalanine by molecular imprinted polymer particlefilled capillary electrochromatography[J].J Liqid Chromatogr Rev Techn,1997,20(10):1489. |
| [29] | 李晓桃,蒋光光,史月华,徐铸德.L-卡尼丁分子压印聚合物作为手性分离色谱固定相的研究[J].分析化学,2002(04):388-391. |
| [30] | 戎非,李萍,冯小刚,袁春伟,付德刚.分子印迹薄层色谱手性固定相的制备及其色谱性能[J].色谱,2006(03):305-308. |
| [31] | 曾昭睿,谢传辉,王园朝,管娜,付恩琴,程介克.溶胶-凝胶法制备丙二酰胺型二氧大环多胺用作开管柱电色谱固定相的研究[J].高等学校化学学报,2001(07):1108-1110. |
| [32] | 孙代红,李良超,韩惠敏,曾昭睿.溶胶-凝胶法制备开链冠醚毛细管气相色谱柱[J].化学通报,2002(03):182-184. |
| [33] | 严丽娟,张庆合,张维冰,冯钰锜,张丽华,李彤,张玉奎.牛血清白蛋白手性毛细管整体柱的制备及对映体的分离[J].高等学校化学学报,2005(05):835-837. |
| [34] | 王东新,Abdul Malik.环糊精-聚硅氧烷共聚物溶胶-凝胶气相色谱毛细管柱分离特性研究[J].分析化学,2005(08):1095-1099. |
| [35] | 江晶,张勇,刘虎威,罗爱芹,邓玉林,顾峻岭.溶胶-凝胶环糊精衍生物CEC开管柱分离TATB炸药副产品[J].北京理工大学学报,2005(04):372-376. |
| [36] | 李良,戴荣继,孟薇薇,邓玉林,傅若农,顾峻岭.溶胶凝胶法制备全丙基-β-CD气相色谱柱的涂渍机理初探[J].北京理工大学学报,2005(10):936-940. |
| [37] | 丁国生,唐安娜.去甲万古霉素键合毛细管电色谱硅胶整体柱的制备及应用[J].色谱,2006(04):402-406. |
| [38] | 张银萍,王东新.溶胶-凝胶法制备耐高温丙三醇毛细管气相色谱柱[J].南京师范大学学报（工程技术版）,2006(02):50-53,80. |
| [39] | Chen Zilin;Katsumi Uchiyama;Toshiyuki Hobo .Chemically modified chiral monolithic silica column prepared by a solgel process for enantiomeric separation by micro high-performance liquid chromatorgraphy[J].Journal of Chromatography A,2002,942:83. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%