本文利用扫描电镜、X射线衍射仪以及红外漫反射仪,并通过对聚乳酸组织工程支架在模拟体液(SBF)中的失重率、分子量以及模拟体液pH值变化的测试,系统地研究了聚乳酸组织工程支架在模拟体液中的降解和矿化性能.结果发现:在模拟体液中,随着时间的增长,聚乳酸组织工程支架的分子量不断下降;但是其重量并不随着时间的增长而减小,而是有升有降.X-射线衍射图谱和FTIR漫反射图谱研究表明,在模拟体液中,聚乳酸组织工程支架的表面有磷灰石沉积物出现.
参考文献
| [1] | T. M. Freyman;I. V. Yannas;L. J. Gibson .Cellular materials as porous scaffolds for tissure engineering[J].Progress in materials science,2001(3-4):273-282. |
| [2] | Ren L;Tsuru K;Hayakawa S;Osaka A .Novel approach to fabricate porous gelatin-siloxane hybrids for bone tissue engineering.[J].Biomaterials,2002(24):4765-0. |
| [3] | Liu X;Ding C;Wang Z .Apatite formed on the surface of plasma-sprayed wollastonite coating immersed in simulated body fluid.[J].Biomaterials,2001(14):2007-2012. |
| [4] | Liu X;Tao S;Ding C .Bioactivity of plasma sprayed dicalcium silicate coatings.[J].Biomaterials,2002(3):963-968. |
| [5] | Liu X;Ding C .Plasma sprayed wollastonite/TiO2 composite coatings on titanium alloys.[J].Biomaterials,2002(20):4065-4077. |
| [6] | Weng J;Wang M;Chen J .Plasma-sprayed calcium phosphate particles with high bioactivity and their use in bioactive scaffolds.[J].Biomaterials,2002(13):2623-2629. |
| [7] | Ning CQ;Zhou Y .In vitro bioactivity of a biocomposite fabricated from HA and Ti powders by powder metallurgy method.[J].Biomaterials,2002(14):2909-2915. |
| [8] | Ding SJ;Su YM;Ju CP;Lin JH .Structure and immersion behavior of plasma-sprayed apatite-matrix coatings.[J].Biomaterials,2001(8):833-845. |
| [9] | Oliveira JM;Correia RN;Fernandes MH .Effects of Si speciation on the in vitro bioactivity of glasses.[J].Biomaterials,2002(2):371-379. |
| [10] | Pham MT.;Matz W.;Reuther H.;Richter E.;Steiner G.;Maitz MF. .Promoted hydroxyapatite nucleation on titanium ion-implanted with sodium[J].Thin Solid Films: An International Journal on the Science and Technology of Thin and Thick Films,2000(1/2):50-56. |
| [11] | Rhee SH;Tanaka J .Effect of citric acid on the nucleation of hydroxyapatite in a simulated body fluid.[J].Biomaterials,1999(22):2155-2160. |
| [12] | Ragel CV;Vallet Regi M;Rodriguez Lorenzo LM .Preparation and in vitro bioactivity of hydroxyapatite/solgel glass biphasic material.[J].Biomaterials,2002(8):1865-1872. |
| [13] | Kweh SW;Khor KA;Cheang P .An in vitro investigation of plasma sprayed hydroxyapatite (HA) coatings produced with flame-spheroidized feedstock.[J].Biomaterials,2002(3):775-785. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%