通过聚乙烯醇(PVA)与丝素(SF)的物理共混制备出PVA/SF共混膜.由SEM观察到SF以100～200nm的球粒形状均匀地分散在PVA中,拉伸实验表明当SF添加量小于40%时,共混膜的拉伸强度和杨氏模量均随SF添加量的增加而提高.采用交互浸渍法在PVA/SF膜上生长羟基磷灰石,经相同交互浸渍周期,在膜表面生成的HA随SF的增加而增加,说明SF具有更强的引导骨组织生长能力.
参考文献
| [1] | Williams S .Mechanical testing of a new biomaterial for potential use as a vascular graft and articular cartilage replacement[D].Georgia Institute of Technology,1998. |
| [2] | Peppas N A;Mongia N K .Ultrapure poly(vinylalcohol) hydrogels with mucoadhesive drug delivery characteristics[J].European Journal of Pharmaceutics and Biopharmaceutics,1997,43:51. |
| [3] | 刘文;吴启崇.国外医学眼科学分册[M].北京:北京大学出版社,1995:80. |
| [4] | 薛毅珑.重视微囊化人工细胞在医学中应用的研究[J].解放军医学杂志,1999(04):235-237. |
| [5] | 李沁华,邹翰.类肝素聚乙烯醇复合材料抗凝血性能的研究[J].中国生物医学工程学报,1999(01):15-21. |
| [6] | 孙瑞焕,毛立江,胡元洁,张颖,王青,朴东旭.离子型聚乙烯醇海绵的结构及性能[J].中国康复理论与实践,2000(02):56-58. |
| [7] | Li M Z;Wu Z Y et al.Study on porous of freeze dried silk fibroin[J].Journal of Applied Polymer Science,2001,79:2185. |
| [8] | Zhang Q Q;Ren L .Structure investigation of poly(vinyl alcohol)-collogen composite[J].Journal of Materials Science and Technology,1997,13(03):179. |
| [9] | 孙东豪,吴徵宇,卢锋.聚乙烯醇/丝素蛋白共混膜的结构与性能研究[J].丝绸,2001(11):6-8. |
| [10] | Rehman I;Bonfield W .Characterization of hydroxyapatite and carbonated apatite by photo acoustic FTIR spectroscopy[J].Journal of Materials Science. Materials in Medicine,1997(1):1-4. |
| [11] | Garcia Alonso MC;Saldana L;Valles G;Gonzalez Carrasco JL;Gonzalez Cabrero J;Martinez ME;Gil Garay E;Munuera L .In vitro corrosion behaviour and osteoblast response of thermally oxidised Ti6Al4V alloy.[J].Biomaterials,2003(1):19-26. |
| [12] | Skoog D A;Holler F J;Nieman T A.Principles of instrumental analysis[A].Philadelphia:Harcourt Brace College Publishers,1997 |
| [13] | Turek S L.Physiology and mineralization of bone[A].Philadelphia:J.B.Lippincott Company,1984:136. |
| [14] | Rusu VM;Ng CH;Wilke M;Tiersch B;Fratzl P;Peter MG .Size-controlled hydroxyapatite nanoparticles as self-organized organic-inorganic composite materials.[J].Biomaterials,2005(26):5414-5426. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%