以壳聚糖为基体,电气石为分散相,采用溶液纺丝法制备电气石/壳聚糖复合纤维,利用光学显微镜、扫描电镜以及红外光谱仪对材料进行表征.电气石/壳聚糖复合纤维与人骨肉瘤细胞株(MG63)体外共培养,初步评价了材料的细胞相容性.结果显示,电气石颗粒在复合纤维中分散均匀且被壳聚糖包裹,纤维表面无裸露电气石.细胞在电气石/壳聚糖复合纤维表面黏附及生长增殖状况良好,材料对细胞无明显毒性.该材料有望成为一种良好的创伤修复敷料.
参考文献
| [1] | 展杰,葛炳辉,王朋.天然热释电材料电气石的微结构及对水的pH值影响机理的研究[J].功能材料,2009(4):556-559.Zhan Jie,Ge Binghui,Wang Peng.Study on the microstructure of natural tourmaline and mechanism of its influence on pH value of water[J].Journal of Functional Materials,2009(4):556-559. |
| [2] | Sahama T G,T6rnroos R.On tourmaline[J].Lithos,1979,12(2):109-114. |
| [3] | 黄城贵,潘丽萍,李海航,等.电气石对绿豆培养细胞生长的影响[J].生物技术,2008,18(3):61-63.Huang Chenggui,Pan Liping,Li Haihang,et al.Tourmaline ceramic balls stimulate growth of mung bean cultural cells[J].Biotechnology,2008,18(3):61-63. |
| [4] | 夏枚生,胡彩虹,张红梅,等.电气石处理水对Caco-2细胞生长和碱性磷酸酶活性的影响[J].细胞生物学杂志,2005,27:358-362.Xia Meisheng,Hu Caihong,Zhang Hongmei,et al.Effects of tourmaline-treated-water on the growth and the activity of alkaline phosphatase of Caco-2 cell[J].Chinese Journal of Coll Biology,2005,27:358-362. |
| [5] | 金惠铭,梁光波,张国平.用Millicell底膜培养皿研究Tourmaline对ECV-304细胞增殖的影响[J].中国微循环2003,7(5):309-311.Jin Huiming,Liang Guangbo,Zhang Guoping.Effects of tourmaline on the proliferation of human endothelial cells using Millicell membrane culture dish[J].Journal of Chinese Microcirculation,2003,7(5):309-311. |
| [6] | 张志湘,冯安生,郭珍旭.电气石的自发极化效应在环境与健康领域的应用[J].中国非金属矿工业导刊,2003,31:47-49.Zhang Zhixiang,Feng Ansheng,Guo Zhenxu.Permanent spontaneous polarization of tourmaline and its application to environment and health field[J].China Non-metallic Mining Industry Herald,2003,31:47-49. |
| [7] | 赵晓伟,张然,崔元臣.壳聚糖-Cu(Ⅱ)对H2O2的分解催化性能研究[J].河南大学学报:自然科学版,2005,35(3):31-36.Zhao Xiaowei,Zhang Ran,Cui Yuanchen.Catalytic property of the chitosan-Cu(Ⅱ) complex for decomposition of H2O2[J].Journal of Henan University:Natural Science,2005,35(3):31-36. |
| [8] | 蒋挺大.壳聚糖[M].北京:化学工业出版社,2006:13.Jiang Tingda.Chitosan[M].Beijing:Chemical Industry Press,2006:13. |
| [9] | 申丙星,胡晓兰,董炎明.可吸收壳聚糖纤维增强壳聚糖棒材[J].复合材料学报,2008,25(6):28-32.Shen Bingxing,Hu Xiaolan,Dong Yanming.Bioabsorable chitosan rod reinforced by chitosan fiber[J].Acta Materiae Compositae Sinica,2008,25(6):28-32. |
| [10] | 赵成如,史文红,金刚.医用敷料[J].中国医疗器械信息,2007(7):15-21.Zhao Chengru,Shi Wenhong,Jin Gang.The medical dressing[J].China Medical Device Information,2007(7):15-21. |
| [11] | 江创生,陈向标.静电纺丝制备生物医用敷科研究进展[J].合成纤维工业,2012,35(3):44-46.Jiang Chuangsheng,Chen Xiangbiao.Research progress of medical dressing prepared by electrospinning[J].China Synthetic Fiber Industry,2012,35(3):44-46. |
| [12] | 国际标准化组织医疗器械生物学评价技术委员会.GB/T16886.5-2003/ISO 10993-5:1 999,医疗器械生物学评价-第5部分:体外细胞毒性试验[S].北京:中华人民共和国国家质量监督检验疫总局,2003.ISO/TC194.GB/T 16886.5-2003/ISO 10993-5:1999,Biological evaluation of medical devices-Fifth section:Cytotoxicity[S].Beijing:Centeral Administration of Quality Supervision,Inspection and Quarantine of the People's Republic of China,2003. |
| [13] | 郝和平.医疗器械生物学评价标准实施指南[M].北京:中国标准出版社,2002:100-110.Hao Heping.Implementation guide for biological evaluation standard of medical devices[M].Beijing:Standards Press of China,2002:100-110. |
| [14] | 李雯雯,吴瑞华,董颖.电气石红外光谱和红外特性的研究[J].高校地质学报,2008,14(3):426-432.Li Wenwen,Wu Ruihua,Dong Ying.Study on infrared spectra and infrared radiation characteristics of tourmaline[J].Geological Journal of China Universities,2008,14(3):426-432. |
| [15] | 赵国骏,姜涌明,孙龙生,等.不同来源壳聚糖的基本特性及红外光谱研究[J].功能高分子学报,1998(11):403-407.Zhao Guojun,Jiang Yongming,Sun Longsheng,et al.The basic characteristics and infrared spectroscopy of the different sources of chitosan[J].Journal of Functional Polymers,1998(11):403-407. |
| [16] | 孙琳,江渊,万方.用红外光谱法测定壳聚糖的脱N-乙酰基度的探讨[J].纺织科学研究,1999(3):9-12.Sun Lin,Jiang Yuan,Wan Fang.Infrared spectroscopy determinations of de-N-acetyl degree of chitosan[J].Textile Science Research,1999(3):9-12. |
| [17] | 董炎明,王勉,吴玉松.壳聚糖衍生物的红外光谱分析[J].纤维素科学与技术,2001,9(2):42-56.Dong Yanming,Wang Mian,Wu Yusong.FTIR spectroscopic determinations of chitosan derivatives[J].Journal of Cellulose Science and Technology,2001,9(2):42-56. |
| [18] | 肖建刚,李峻峰,邱克辉,等.电气石/壳聚糖复合纤维制备与表征[J].功能材料,2012,43(增刊Ⅰ):78-80.Xiao Jiangang,Li Junfeng,Qiu Kehui,et al.Preparation and characterization of tourmaline/chitosan composite fiber[J].Journal of Functional Materials,2012,43(S1):78-80. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%