目的：提高医用钛合金的抗菌性能。方法应用直流磁控溅射在 Ti6Al4V 基体上沉积 Ti-Cu-N薄膜，通过平板计数法和细菌活死染色对比研究薄膜和基材的抗菌性能。采用扫描电子显微镜、X 射线衍射仪和辉光放电光谱分析仪研究薄膜的微观组织、化学成分分布。结果 Ti-Cu-N 薄膜对大肠杆菌展现了优良抗菌性能。结论 Ti-Cu-N 薄膜能够很好地改善 Ti6Al4V 合金的抗菌性能。
Objective To improve the antibacterial properties of medical titanium alloys. Methods Ti-Cu-N films were deposi-ted on Ti6Al4V substrates by magnetron sputtering. The antibacterial analyses employed the fluorescence staining method and bac-terial-viability tests on agar plates. The microstructure and the chemical composition were characterized using scanning electron microscope (SEM), X-ray diffraction (XRD) and glow discharge optical emission spectroscope (GDOES) technique. Results The Ti-Cu-N coating exhibited excellent antibacterial properties against Escherichia coli. Conclusion The Ti-Cu-N coating prepared could greatly improve the antimicrobial properties of the Ti6Al4V alloy.
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