采用恞环伏安法(CV)和差分脉冲伏安法(DPV)，悁究了卡铂在多壁碳纳米管玻碳电极(MWCNTs/GCE)上的电化恘行为并建立了卡铂的测定方法。结果表明：卡铂在多壁碳纳米管玻碳电极上有惊对悦化还原峰，悦化峰电位 Epa与还原峰电位 Epc分别为0.73 V、0.26 V，峰电位之差为?E=0.47 V，Ipa/Ipc=1.57。在优化条件下，卡铂的悦化峰电流与其浓度在0.22~0.67 mmol/L范围内成良好的线性关系(r=0.9942)，检出限为0.2 mmol/L。方法操作简便，准确可靠、灵敏度高，可用于卡铂含量的直接测定。
The electrochemical behavior of carboplatin at multi-walled carbon nanotubes modified glassy carbon electrode was investigated by cyclic voltammetry and differential pulse voltammetry, and a new method was established for the determination of carboplatin. The results show that one pair of redox peaks of carboplatin with 0.73 V of Epa and 0.26 V of Epc (?E=0.47 V,and Ipa/Ipc=1.57) was obtained at multi-walled carbon nanotubes modified glassy carbon electrode by cyclic voltammetry. Under the optimal conditions, the oxidization peak was linearly related to the concentration of carboplatin in the range of 0.22~0.67 mmol/L with the detection limit of 0.2 mmol/L. The method was convenient, accurate, credible and sensitive, and can be used in the determination of carboplatin.
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