探讨了壳聚糖/聚乙烯醇水凝胶的制备方法,研究了聚乙烯醇与壳聚糖质量比、溶剂醋酸溶液体积、交联剂戊二醛浓度等对水凝胶硬度的影响.正交实验结果表明当聚乙烯醇与壳聚糖质量比为6、溶剂醋酸体积为80mL、交联剂戊二醛浓度为0.426mol/L时,凝胶硬度为132.643kPa.凝胶硬度随着聚乙烯醇与壳聚糖质量比和交联剂戊二醛浓度的增大而增大,随着溶剂醋酸溶液体积的增加而减小,随着凝胶温度的升高先增大后减小,壳聚糖/聚乙烯醇凝胶硬度随着放置时间的延长而逐渐增大,PVA-124与壳聚糖制备的凝胶硬度最大.
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