采用溶液共混法将β-环糊精（β-CD）添加到聚乙烯醇（PVA）中,然后通过冷冻-解冻法制备了PVA和β-CD复合水凝胶。通过核磁共振、红外、扫描电镜、X射线衍射、热重分析对材料的结构与性能进行表征,并研究了材料的亲疏水性及其细胞相容性。结果表明PVA和β-CD可用于制备新型PVA/β-CD复合水凝胶。通过改变β-CD的添加量可调节复合水凝胶的亲疏水性。初步体外细胞实验表明该复合水凝胶无细胞毒性。PVP/β-CD复合水凝胶是一种有发展前景的生物材料。
Poly（vinyl alcohol） /β-cyclodextrin（PVA/β-CD） composite hydrogels were prepared by co-solution method and treated with repeated freeze-thawing recycle.The composite material was analyzed by nuclear magnetic resonance,infrared spectroscopy,scanning electron microscopy,X-ray diffraction and thermogravimetric analysis.The hydrophilicity and cytocompatibility were also tested.The results showed that new hybrid system of PVA/β-CD had been successfully prepared.The hydrophilicity of the composite can be adjusted by the amount of β-CD.The PVA/β-CD composite hydrogel exhibited good cytocompatibility,showing promising prospect as a new biomaterial.
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