Effect of Long-term Intake of Rare Earth in Drinking Water on Trace Elements in Brains of Mice

稀土学报(英文版), 2002, 20(5): 562-564.

刘洁生 ^1, , 申治国 ^2, , 杨维东 ^3, , 车军 ^4, , 谢利民 ^5, , 雷衡毅 ^6,

1.Department of Biotechnology, Jinan University, Guangzhou 510632, China

2.Shenzhen Center for Disease Control and Prevention, Shenzhen 518020, China

3.Department of Biotechnology, Jinan University, Guangzhou 510632, China

4.Department of Biotechnology, Jinan University, Guangzhou 510632, China

5.Department of Biotechnology, Jinan University, Guangzhou 510632, China

6.School of Earth and Environment Science, Zhongshan University, Guangzhou 510275, China

基金项目: 广东省自然科学基金(980329) the Medical Scientific Research Foundation of Guangdong Province(A2001637)

Effect of Long-term Intake of Rare Earth in Drinking Water on Trace Elements in Brains of Mice

Keywords： rare earths

The mice were fed with water dissolved different level Y3+ (0, 23.25, 2325.00 mg*L-1) for seven months, and the levels of trace elements such as Cu, Zn, Mn, Fe, Mg, Ni and Co in brains of F1 generation mice were then determined by POEMS. The results show that, compared with control, significant decreases in levels of Fe and Ni, increase in level of Co are observed, which suggested that Y3+ may have an effect on the metabolism and distribution of some trace elements in brain, and then lead to changes of physiological function.

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Effect of Long-term Intake of Rare Earth in Drinking Water on Trace Elements in Brains of Mice

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