采用分子自组装(SAM)方法在医用钛表面制备了硫酸软骨素薄膜.通过激光共聚焦显微镜,傅立叶红外光谱,X射线光电子能谱以及接触角测定仪等分析测试手段,比较研究了表面预处理方法的活化作用以及成膜反应时间对自组装薄膜的影响规律.实验结果表明,用等体积比的浓硫酸和双氧水混合溶液在75C对钛表面处理1h后的钛片能获得最高的表面自由能,而自组装膜的反应在12h内即可完成.
参考文献
| [1] | Nanci A;Wuest JD;Peru L;Brunet P;Sharma V;Zalzal S;McKee MD .Chemical modification of titanium surfaces for covalent attachment of biological molecules.[J].Journal of biomedical materials research, Part B. Applied biomaterials,1998(2):324-335. |
| [2] | Kokubo T.;Kim HM.;Nakamura T.;Miyaji F. .SPONTANEOUS FORMATION OF BONELIKE APATITE LAYER ON CHEMICALLY TREATED TITANIUM METALS[J].Journal of the American Ceramic Society,1996(4):1127-1129. |
| [3] | P Li;Ohtsuki C;Kokubo T et al.[J].Journal of Biomedical Materials Research,1994,28:7-15. |
| [4] | Feng B;Chen JY;Qi SK;He L;Zhao JZ;Zhang XD .Carbonate apatite coating on titanium induced rapidly by precalcification.[J].Biomaterials,2002(1):173-179. |
| [5] | 应佩青,王战会,靳刚,陶祖莱.利用自组装单分子层（SAM）研究细胞和表面的相互作用[J].生物医学工程学杂志,2001(02):276-279. |
| [6] | Huang D.;Gu JH.;Huang NP.;Yuan CW.;Xiao ZD. .TIO2 THIN FILMS FORMATION ON INDUSTRIAL GLASS THROUGH SELF-ASSEMBLY PROCESSING[J].Thin Solid Films: An International Journal on the Science and Technology of Thin and Thick Films,1997(1/2):110-115. |
| [7] | Qing Liu;Jiang Ding;Francis K Mante et al.[J].Biomaterials,2002,23:3103-3111. |
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