聚氨酯由于其优良的机械性能和生物相容性而广泛应用于生物医用材料,如制作人工器官、药物释放载体及人工血管等.但是当它作为体内移植材料使用时会引起机体的炎症反应,并且与血液接触时还会引起持续的凝血和内膜增生.因此,要想将聚氨酯应用于人工血管,就要进一步提高它的生物相容性、血液相容性和细胞相容性等.目前主要是通过对聚氨酯进行本体改性、表面接枝聚合改性、等离子体处理聚氨酯表面、涂覆生物分子及结构设计等方法来提高其在体内使用时的性能.
参考文献
| [1] | Zhang L;Zhou JY;Lu QP;Wei YJ;Hu SS .A novel small-diameter vascular graft: In vivo behavior of biodegradable three-layered tubular scaffolds[J].Biotechnology and Bioengineering,2008(4):1007-1015. |
| [2] | McKee JA;Banik SSR;Boyer MJ;Hamad NM;Lawson JH;Niklason LE .Human arteries engineered in vitro[J].EMBO Journal,2003(6):633-638. |
| [3] | Wang X W;Lin P;Yao Q Z et al.Development of small-diameter vascular grafts[J].World Journal of Surgery,2007,31(04):682-689. |
| [4] | Veith F J;Moss C M;Sprayregen S et al.Propertive saphenous venography in arterial reconstructive surgery of the lower extremity[J].Surgery,1979,85(03):253-256. |
| [5] | Edwards W S;Holdefer W F;Mohtashemi M .The importance of proper caliber of lumen in femoral-popliteal artery reconstruction[J].Surgery Gynecology and Obstetrics,1966,122(01):37-40. |
| [6] | Murray W J;Lyman D J;Wijelath E S .Vascular graft healing Ⅲ FT-IR analysis of ePTFE graft samples from implanted bigrafts[J].Journal of Biomedical Materials Research Part B:Applied Biomaterials,2004,70(02):223-232. |
| [7] | Cho E H;Yang Y I;Mun C W et al.Tissue-engineered semi-microporous segmented polyetherurethane vascular prostheses[J].Journal of Biomaterials Science:Polymer Edition,2005,16(06):775-790. |
| [8] | Kannan RY;Salacinski HJ;Butler PE;Hamilton G;Seifalian AM .Current status of prosthetic bypass grafts: a review.[J].Journal of biomedical materials research, Part B. Applied biomaterials,2005(1):570-581. |
| [9] | Fred J D;Geoffrey R M.Polyurethane based materials with applications in medical devices[A].New York:Springer Science,Business Media,2008 |
| [10] | Xie, X.;Eberhart, A.;Guidoin, R.;Marois, Y.;Douville, Y.;Zhang, Z. .Five types of polyurethane vascular grafts in dogs: The importance of structural design and material selection[J].Journal of biomaterials science,2010(8/9):1239-1264. |
| [11] | Williams S K;Rose D G;Jarrell B E .Microvascular endothelial cell sodding of ePTFE vascular grafts:improved patency and stability of the cellular lining[J].Journal of Biomedical Materials Research,1994,28(02):203-212. |
| [12] | Kiyama H;Imazeki T;Kurihara S;Yoneshima H .Long-term follow-up of polyurethane vascular grafts for hemoaccess bridge fistulas.[J].Annals of vascular surgery,2003(5):516-521. |
| [13] | Kannan RY;Salacinski HJ;Butler PE;Hamilton G;Seifalian AM .Current status of prosthetic bypass grafts: a review.[J].Journal of biomedical materials research, Part B. Applied biomaterials,2005(1):570-581. |
| [14] | Grasl,C.;Bergmeister,H.;Stoiber,M.;Schima,H.;Weigel,G. .Electrospun polyurethane vascular grafts: In vitro mechanical behavior and endothelial adhesion molecule expression[J].Journal of biomedical materials research, Part A,2010(2):716-723. |
| [15] | Wang Z;Liu S;Guidoin R;Kodama M .Polyurethane vascular grafts with thorough porosity: does an internal or an external membrane wrapping improve their in vivo blood compatibility and biofunctionality?[J].Artificial cells, blood substitutes, and immobilization biotechnology,2004(3):463-484. |
| [16] | Yaguchi T;Funakubo A;Okoshi T;Noishiki Y;Fukui Y .Fabrication of small-diameter polyurethane vascular grafts with microporous structure[J].Journal of artificial organs: The official journal of the Japanese Society for Artificial Organs,2002(2):117-122. |
| [17] | Miyamoto K;Sugimoto T;Okada M;Maeda S .Usefulness of polyurethane for small-caliber vascular prostheses in comparison with autologous vein graft[J].Journal of artificial organs: The official journal of the Japanese Society for Artificial Organs,2002(2):113-116. |
| [18] | Jeschke MG;Hermanutz V;Wolf SE;Koveker GB .Polyurethane vascular prostheses decreases neointimal formation compared with expanded polytetrafluoroethylene.[J].Journal of vascular surgery,1999(1):168-176. |
| [19] | Shin J W;Shin H J;Heo S J.Hybrid nanofiber scaffolds of polyurethane and poly(ethylene oxide) using dual-electrospinning for vascular tissue engineering[A].Kuala Lumpur,2006 |
| [20] | Taite LJ;Yang P;Jun HW;West JL .Nitric oxide-releasing polyurethane-PEG copolymer containing the YIGSR peptide promotes endothelialization with decreased platelet adhesion.[J].Journal of biomedical materials research, Part B. Applied biomaterials,2008(1):108-116. |
| [21] | Seifalian AM;Salacinski HJ;Tiwari A;Edwards A;Bowald S;Hamilton G .In vivo biostability of a poly(carbonate-urea)urethane graft.[J].Biomaterials,2003(14):2549-2557. |
| [22] | Chuang TW;Masters KS .Regulation of polyurethane hemocompatibility and endothelialization by tethered hyaluronic acid oligosaccharides.[J].Biomaterials,2009(29):5341-5351. |
| [23] | Keogh JR.;Overend ME.;Tang LP.;Eaton TW.;Wolf MF. .BIOCOMPATIBILITY OF SULPHONATED POLYURETHANE SURFACES[J].Biomaterials,1996(20):1987-1994. |
| [24] | Ivanchenko M I;Kulik E A;Ikada Y.Serum protein adsorption and platelet adhesion to polyurethane grafted with methoxypoly(ethylene glycol) methacrylate polymers[A].Washington,1995:463-477. |
| [25] | Sidouni FZ.;Chabrecek P.;Lohmann D.;Vogt J.;Xanthopoulos N. Mathieu HJ.;Francois P.;Vaudaux P.;Descouts P.;Nurdin N. .Surface properties of a specifically modified high-grade medical polyurethane[J].Surface Science: A Journal Devoted to the Physics and Chemistry of Interfaces,2001(3):355-369. |
| [26] | Ayse E Aksoy;Vasif Hasirci;Nesrin Hasirci.Surface Modification of Polyurethanes with Covalent Immobilization of Heparin[J].Macromolecular symposia,2008:145-153. |
| [27] | Kawamoto, Y;Nakao, A;Ito, Y;Wada, N;Kaibara, M .Endothelial cells on plasma-treated segmented-polyurethane - Adhesion strength, antithrombogenicity and cultivation in tubes[J].Journal of Materials Science. Materials in Medicine,1997(9):551-557. |
| [28] | Kaibara M;Takahashi A;Kurotob K et al.Proliferation of endothelial cells on the plasma-treated segmented-polyurethane surface:attempt of construction of a small caliber hybrid vascular graft and antithrombogenicity[J].Colloids and Surfaces B:Biointerfaces,2000,19(03):209-217. |
| [29] | Lim, HR;Baek, HS;Lee, MH;Woo, YI;Han, DW;Han, MH;Baik, HK;Choi, WS;Park, KD;Chung, KH .Surface modification for enhancing behaviors of vascular endothelial cells onto polyurethane films by microwave-induced argon plasma[J].Surface & Coatings Technology,2008(22/23):5768-5772. |
| [30] | Soletti L;Nieponice A;Hong Y et al.In vivo performance of a phospholipid-coated bioerodable elastomeric graft for small-diameter vascular applications[J].Journal of Biomedical Materials Research Part A,2011,96(02):436-448. |
| [31] | Aldenhoff Y B J;Veen F H;Woorst J et al.Performance of a polyurethane vascular prosthesis carrying a dipyridamole (persantint) coating on its lumenal surface[J].Journal of Biomedical Materials Research,2001,54(02):224-233. |
| [32] | Miyazu,K.;Kawahara,D.;Ohtake,H.;Watanabe,G.;Matsuda,T. .Luminal surface design of electrospun small-diameter graft aiming at in situ capture of endothelial progenitor cell[J].Journal of biomedical materials research, Part B. Applied biomaterials,2010(1):53-63. |
| [33] | Goodman SL.;Albrecht RM.;Sims PA. .THREE-DIMENSIONAL EXTRACELLULAR MATRIX TEXTURED BIOMATERIALS[J].Biomaterials,1996(21):2087-2095. |
| [34] | Meng,J.;Han,Z.;Kong,H.;Qi,X.;Wang,C.;Xie,S.;Xu,H. .Electrospun aligned nanofibrous composite of MWCNT/polyurethane to enhance vascular endothelium cells proliferation and function[J].Journal of biomedical materials research, Part A,2010(1):312-320. |
| [35] | Ozkucur N;Wetzel C;Hollstein F;Richter E;Funk RH;Monsees TK .Physical vapor deposition of zirconium or titanium thin films on flexible polyurethane highly support adhesion and physiology of human endothelial cells.[J].Journal of biomedical materials research, Part A,2009(1):57-67. |
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