可吸收珊瑚羟基磷灰石的制备及兔胫骨缺损修复效果观察

功能材料, 2004, 35(z1): 2405-2407.

可吸收珊瑚羟基磷灰石的制备及兔胫骨缺损修复效果观察

陈德夫 ^1, , 宋正孝 ^2, , 范丽娟 ^3, , 袁宁 ^4, , 田伟 ^5,

1.北京市意华健科贸有限责任公司,北京,100035

2.天津大学,化工学院,天津,300072

3.北京市意华健科贸有限责任公司,北京,100035

4.北京积水潭医院,脊柱外科,北京,100045

5.北京积水潭医院,脊柱外科,北京,100045

关键词：可吸收珊瑚羟基磷灰石 , 制备 , 骨缺损 , 修复 , 多孔陶瓷

Preparation of resorbable coralline hydroxyapatite and observation on its effects to repair tibial defect in rabbits

以特定的珊瑚为原料,制备出一种可吸收的多孔复合陶瓷--可吸收珊瑚羟基磷灰石(R-CHA).通过XRD、光镜和电镜等方法对材料进行观察分析.结果表明其主要成分是碳酸钙和羟基磷灰石,由羟基磷灰石薄层覆盖在碳酸钙骨架的表面,同时具有孔孔相通的三维结构.兔胫骨缺损修复实验显示,该材料具有很好的生物相容性、骨传导性和成骨性,并可随新骨的生成在预计的时间内逐渐吸收.

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可吸收珊瑚羟基磷灰石的制备及兔胫骨缺损修复效果观察

Preparation of resorbable coralline hydroxyapatite and observation on its effects to repair tibial defect in rabbits

参考文献