新型双酚类抗氧剂2,2′-亚甲基双（6-壬基对甲酚）的合成

合成材料老化与应用, 2014, (6): 33-36.

新型双酚类抗氧剂2,2′-亚甲基双（6-壬基对甲酚）的合成

李世昌 ^1, , 敖晓娟 ^2, , 王庆 ^3, , 苑丽红 ^4, , 谭卓华 ^5,

1.广州合成材料研究院有限公司,广东广州,510665

2.广州合成材料研究院有限公司,广东广州,510665

3.广州合成材料研究院有限公司,广东广州,510665

4.广州合成材料研究院有限公司,广东广州,510665

5.广州合成材料研究院有限公司,广东广州,510665

关键词：双酚 , 抗氧剂 , 2 , 2′-亚甲基双(6-壬基对甲酚)

The Synthesis of Novel Diphenol Antioxidant 2,2′-methylenebis(6-nonyl-p-cresol)

Keywords： diphenol , antioxidant , 2 , 2′-methylenebis(6-nonyl-p-cresol)

抗氧剂2,2′-亚甲基双(6-壬基对甲酚)是新型大分子量液体双酚类抗氧剂,我们以对甲酚为原料,通过酯化反应、Fries重排反应、傅克酰化反应、羰基Clemmensen还原反应和酸介导的甲醛亲和取代反应合成了2,2′-亚甲基双(6-壬基对甲酚),中间体和最终产物都通过NMR、MS表征确证,以大于90%的总收率实现产品的合成。

Diphenol antioxidant,2,2′-methylenebis(6-nonyl-p-cresol),is a novel liquid diphenol antioxidant with high molecular weight,which was synthesized with crude material p-cresol. The target molecule was achieved by esterification,Fries rearrangement,Friedel-Crafts acylation,Clemmensen reduction and acid-mediated nucleophil-ic substitution reactions. All intermediate and final compounds were fully characterized by NMR and MS,and the total yield is more than 90% in about 4 steps.

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