以氢氧化钙和正硅酸四乙酯为原料,采用共沉淀法制备出了一系列的水化硅酸钙(CSH),通过X射线衍射(XRD)、扫描电子显微镜(SEM)等探讨了不同的酒精添加量和有机溶剂添加对CSH的物相和形貌的影响.结果表明；随着酒精添加量的增加CSH的分散性逐渐变好,采用丙三醇作为有机溶剂可以得到分散较好CSH微球.对CSH进行了布洛芬(IBU)载药研究,利用热重-差热分析、Brunauer-Emmett-Teller法和红外光谱表征(FT-IR)合对其在不同载药时间的CSH载药量、比表面积、孔容和表面基团等进行了分析.发现在12 h后载药量达到116.78％,有望成为较好的药物载体材料.
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