首先介绍了原子力显微镜(AFM)在ATP合成酶表面超精细结构表征中的应用,AFM同其它生化技术相结合研究ATP合成酶结构细节的相关工作,在ATP合成酶超分子表面的粘弹性、电荷分布、磁畴分布、分子间相互作用等物理属性研究中的试验进展;总结了AFM在ATP合成酶分子功能研究和单分子操纵中的应用情况;最后,综合上述试验进展现状,对仪器的机械改进和理论发展及在蛋白分子研究中的应用前景进行了讨论.
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