以N-苯基马来酰亚胺（NPMI）和4-乙烯基吡啶-醋酸锌配合物（4VP-Zn（Ac）2）为单体,用可逆断裂链转移聚合（RAFT）方法合成了两亲性聚（N-苯基马来酰亚胺）-b-聚（4-乙烯基吡啶）-ZnS（PNPMI-b-P4VP-ZnS）高分子纳米复合物（PNCs）,用核磁共振（NMR）、X射线衍射（XRD）、扫描电镜（SEM）和透射电镜（TEM）等对产物进行了表征。随着RAFT嵌段聚合时间由1 h增加到30 h,PNPMI-b-P4VP-ZnS中ZnS的质量分数由8.2%提高到12.6%,ZnS粒径由3 nm增大到200 nm,并由立方向六方晶型转变,复合物中PNPMI-b-P4VP的荧光强度逐渐下降,而ZnS的荧光强度逐渐增大。研究表明,RAFT方法可有效调控PNPMI-b-P4VP和ZnS之间的荧光共振能量转移。PNPMI-b-P4VP-ZnS在生物研究领域具有潜在的应用价值。
The amphipathic poly（N-phenylmaleimide）-b-poly（4-vinylpyridine）-zinc acetate（PNPMI-b-P4VP-Zn（Ac）2） complex has been synthesized by reversible addition fragmentation chain transfer（RAFT） polymerization,using N-phenylmaleimide and 4-vinylpyridine-zinc acetate（4VP-Zn（Ac）2） as monomers.The products as prepared have been characterized by nuclear magnetic resonance spectrum（NMR）,X-ray diffraction（XRD）,scanning electron microscope（SEM） and transmission electron microscope（TEM）.The ZnS mass fraction increases from 8.2% to 12.6% with the block copolymerization time increasing from 1h to 30h.The particle size of ZnS also increases from 3 nm to 200 nm,accompanied with the crystal style conversion of ZnS from cubic to hexagonal.The photoluminescence（PL） intensity of PNPMI-b-P4VP decreases with the increasing block copolymerization time,however,the PL intensity of ZnS increases.Results show that,the fluorescence resonance energy transfer properties between PNPMI-b-P4VP and ZnS are controllable by RAFT method.The PNPMI-b-P4VP-ZnS FRET probe shows a potential application in the biologic field.
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