采用原位沉析法制备了壳聚糖/羟基磷灰石(CS/HA)复合棒材.用预先沉积的壳聚糖膜将含有Ca、P源的壳聚糖溶液与凝固液隔离,同时控制壳聚糖沉积与羟基磷灰石前驱体转化为羟基磷灰石的过程,使二者得以均匀复合.燃烧试验结果表明无机成分均匀分散于壳聚糖中,FT-IR、XRD和TEM测试证实原位生成羟基磷灰石,弯曲强度测试结果表明,原位沉析法制备的材料具有层状结构,CS/HA(质量比20/4)复合材料弯曲强度达133MPa,弯曲模量6.8GPa.
参考文献
| [1] | 马元璋;万鹏.临床骨内固定学[M].合肥:安徽科学技术出版社,1999:45. |
| [2] | Liu Jingxiao;Shi Fei;Yu Ling et al.[J].Journal of Materials Science and Technology,2009,25(04):551-555. |
| [3] | Cai X;Tong H;Shen X .Preparation and characterization of homogeneous chitosan-polylactic acid/hydroxyapatite nanocomposite for bone tissue engineering and evaluation of its mechanical properties.[J].Acta biomaterialia,2009(7):2693-2703. |
| [4] | 张利,李玉宝,魏杰,左奕,韩纪梅,吴兰,王学江.纳米羟基磷灰石/壳聚糖复合骨修复材料的共沉淀法制备及其性能表征[J].功能材料,2005(03):441-444. |
| [5] | Hu Q;Li B;Wang M;Shen J .Preparation and characterization of biodegradable chitosan/hydroxyapatite nanocomposite rods via in situ hybridization: a potential material as internal fixation of bone fracture.[J].Biomaterials,2004(5):779-785. |
| [6] | Davidenko N;Carrodeguas RG;Peniche .Chitosan/apatite composite beads prepared by in situ generation of apatite or Si-apatite nanocrystals.[J].Acta biomaterialia,2010(2):466-476. |
| [7] | 李保强,胡巧玲,汪茫,沈家骢.原位复合法制备层状结构的壳聚糖/羟基磷灰石纳米材料[J].高等学校化学学报,2004(10):1949-1952. |
| [8] | Ferndndez E;Gil F J;Best S M et al.[J].Journal of Biomedical Materials Research Part A,1998,41(04):560-567. |
| [9] | Bohner M;vanLanduyt P;Merkle HP;Lemaitre J .Composition effects on the pH of a hydraulic calcium phosphate cement[J].Journal of Materials Science. Materials in Medicine,1997(11):675-681. |
| [10] | Marcia R. de Moura;Fauze A. Aouada;Roberto J. Av .Improved Barrier And Mechanical Properties Of Novel Hydroxypropyl Methylcellulose Edible Films With Chitosan/tripolyphosphate Nanoparticles[J].Journal of food engineering,2009(4):448-453. |
| [11] | 戴红莲,闫玉华,李世普,贺建华.α-磷酸三钙-磷酸四钙生物骨水泥的研究[J].材料科学与工程,2002(03):331-335. |
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