欢迎登录材料期刊网

材料期刊网

高级检索

纳米材料所具有的特殊物理、化学性质,使其及相关技术成为当今科学研究的前沿热点.然而,随着纳米技术的迅速发展,人们对纳米材料安全性及其生物效应的信息需求不断增加,纳米材料的毒性及其时环境的影响已经引起科学界和政府有关部门的重视.综述了纳米微粒侵染生物体的途径及其毒性的影响因素,并详细阐述了近几年来关于纳米材料毒性研究的最新进展,最后对纳米工业生产中应加强的问题进行了讨论.

参考文献

[1] Vincent W H;Eileen M .Nanotechnology[J].J Chem Health Safety,2008,15(02):10.
[2] S.K.Sahoo PhD;S.Parveen MS;J.J.Panda MS .The present and future of nanotechnology in human health care[J].Nanomedicine: Nanotechnology, Biology and Medicine,2007(1):20-31.
[3] Lord P G;Papoian T .Genomics and drug toxicity[J].Science,2004,306(5696):575.
[4] X. Michalet;F. F. Pinaud;L. A. Bentolila;J. M. Tsay;S. Doose;J. J. Li;G. Sundaresan;A. M. Wu;S. S. Gambhir;S. Weiss .Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics[J].Science,2005(5709):538-544.
[5] Nel A;Xia T;Madler L;Li N .Toxic potential of materials at the nanolevel.[J].Science,2006(5761):622-627.
[6] Vega-Villa KR;Takemoto JK;Yanez JA;Remsberg CM;Forrest ML;Davies NM .Clinical toxicities of nanocarrier systems.[J].Advanced drug delivery reviews,2008(8):929-938.
[7] Nel A .Air pollution-related illness:Effects of particles[J].Science,2005,308(5723):804.
[8] Colvin V .Correlating the physical and chemical properties of nanoparticles to their biological activity environ[J].Mol Mutagen,2007,48:533.
[9] Mortensen LJ;Oberdorster G;Pentland AP;DeLouise LA .In vivo skin penetration of quantum dot nanoparticles in the murine model: The effect of UVR[J].Nano letters,2008(9):2779-2787.
[10] Rouse JG;Haslauer CM;Loboa EG;Monteiro-Riviere NA .Cyclic tensile strain increases interactions between human epidermal keratinocytes and quantum dot nanoparticles.[J].Toxicology in vitro: an international journal published in association with BIBRA,2008(2):491-497.
[11] Petri-Fink A et al.Effect of cell media on polymer coated superpararnagnetic iron oxide nanoparticles (SPIONs):Colloidal stability,cytotoxicity,and cellular uptake studies European[J].Journal of Pharmacokinetics and Biopharmaceutics,2008,68(01):129.
[12] Magrez A;Kasas S;Salicio V;Pasquier N;Seo JW;Celio M;Catsicas S;Schwaller B;Forro L .Cellular toxicity of carbon-based nanomaterials[J].Nano letters,2006(6):1121-1125.
[13] Austin M. Derfus;Warren C. W. Chan;Sangeeta N. Bhatia .Probing the Cytotoxicity of Semiconductor Quantum Dots[J].Nano letters,2004(1):11-18.
[14] He X;Ma J;Mercado AE;Xu W;Jabbari E .Cytotoxicity of Paclitaxel in biodegradable self-assembled core-shell poly(lactide-co-glycolide ethylene oxide fumarate) nanoparticles.[J].Pharmaceutical research,2008(7):1552-1562.
[15] SCOTT C.BROWN;MOHAMMED KAMAL;NAJMUNNISA NASREEN .Influence of shape,adhesion and simulated lung mechanics on amorphous silica nanoparticle toxicity[J].Advanced Powder Technology: The internation Journal of the Society of Powder Technology, Japan,2007(1):69-79.
[16] Lovric J;Bazzi HS;Cuie Y;Fortin GR;Winnik FM;Maysinger D .Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots.[J].Journal of molecular medicine: Official organ of the "Gesellschaft Deutscher Naturforscher und Arzte.",2005(5):377-385.
[17] Klaus Wittmaack .In Search of the Most Relevant Parameter for Quantifying Lung Inflammatory Response to Nanoparticle Exposure:Particle Number,Surface Area,or What?[J].Environmental health perspectives,2007(2):187-194.
[18] Maureen R.Gwinn;Val Vallyathan .Nanoparticles:Health Effects-Pros and Cons[J].Environmental health perspectives,2006(12):1818-1825.
[19] Brook R D;Franklin B;Teger I .Air pollution and cardiovascular disease:a statement for healthcare professionals from the expert panel on population and prevention[J].Sci Am Heart Assoc Circulation,2004,109(21):2655.
[20] Xia T;Kovochich M;Brant J;Hotze M;Sempf J;Oberley T;Sioutas C;Yeh JI;Wiesner MR;Nel AE .Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm[J].Nano letters,2006(8):1794-1807.
[21] Casey A;Herzog E;Lyng FM;Byrne HJ;Chambers G;Davoren M .Single walled carbon nanotubes induce indirect cytotoxicity by medium depletion in A549 lung cells.[J].Toxicology Letters: An International Journal Providing a Forum for Original and Pertinent Contributions in Toxicology Research,2008(2):78-84.
[22] Poland CA;Duffin R;Kinloch I;Maynard A;Wallace WAH;Seaton A;Stone V;Brown S;MacNee W;Donaldson K .Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study[J].Nature nanotechnology,2008(7):423-428.
[23] Sayes CM;Gobin AM;Ausman KD;Mendez J;West JL;Colvin VL .Nano-C-60 cytotoxicity is due to lipid peroxidation[J].Biomaterials,2005(36):7587-7595.
[24] Markovic Z;Todorovic-Markovic B;Kleut D;Nikolic N;Vranjes-Djuric S;Misirkic M;Vucicevic L;Janjetovic K;Isakovic A;Harhaji L;Babic-Stojic B;Dramicanin M;Trajkovic V .The mechanism of cell-damaging reactive oxygen generation by colloidal fullerenes.[J].Biomaterials,2007(36):5437-5448.
[25] Choi AO;Brown SE;Szyf M;Maysinger D .Quantum dot-induced epigenetic and genotoxic changes in human breast cancer cells.[J].Journal of molecular medicine: Official organ of the "Gesellschaft Deutscher Naturforscher und Arzte.",2008(3):291-302.
[26] Huczko A;Lange H;Calko E et al.Physiological testing of carbon nanotubes:are they asbestos-like ullerene[J].Science Technology,2001,9(02):251.
[27] Soo-Choi H;Liu W;Misra P;Tanaka E;Zimmer JP;Itty-Ipe B;Bawendi MG;Frangioni JV .Renal clearance of quantum dots.[J].Nature biotechnology,2007(10):1165-1170.
[28] Leroueil PR;Berry SA;Duthie K;Han G;Rotello VM;McNerny DQ;Baker JR;Orr BG;Holl MMB .Wide varieties of cationic nanoparticles induce defects in supported lipid bilayers[J].Nano letters,2008(2):420-424.
[29] Seungpyo Hong;Anna U.Bielinska;Almut Mecke;Balazs Keszler;James L.Beals;Xiangyang Shi;Lajos Balogh;Bradford G.Orr;James R.Baker;Mark M.Banaszak Holl .Interaction of Poly(amidoamine) Dendrimers with Supported Lipid Bilayers and Cells:Hole Formation and the Relation to Transport[J].Bioconjugate Chemistry,2004(4):774-782.
[30] Seungpyo Hong;Pascale R.Leroueil;Elizabeth K.Janus;Jennifer L.Peters;Mary-Margaret Kober .Interaction of Polycationic Polymers with Supported Lipid Bilayers and Cells:Nanoscale Hole Formation and Enhanced Membrane Permeability[J].Bioconjugate Chemistry,2006(3):728-734.
[31] Tarl W P;Imran B;Gerard A L et al.Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium[J].Nanomedicine-Nanotechnology Biology and Medicine,2008,4(04):340.
[32] Di Pasqua AJ;Sharma KK;Shi YL;Toms BB;Ouellette W;Dabrowiak JC;Asefa T .Cytotoxicity of mesoporous silica nanomaterials[J].Journal of Inorganic Biochemistry: An Interdisciplinary Journal,2008(7):1416-1423.
上一张 下一张
上一张 下一张
计量
  • 下载量()
  • 访问量()
文章评分
  • 您的评分:
  • 1
    0%
  • 2
    0%
  • 3
    0%
  • 4
    0%
  • 5
    0%