针对压实的羟基磷灰石／壳聚糖复合材料在水中会发生崩裂，采用水蒸汽处理方法，利用XRD、FTIR和SEM对处理前后块体复合材料的组成、结构和断面形态进行分析，考察了温度和处理时间对复合材料压片抗水情况的影响。结果表明，水蒸汽处理可以促进复合材料分子间氢键的形成并有利于HA的Ca^2＋与壳聚糖的-NH2和-OH离子间络合作用的增强，从而防止羟基磷灰石／壳聚糖复合材料薄片遇水时发生崩裂，抗水性能得到提高，在这一过程中水蒸汽压或温度是主要影响因素。
To prevent hydroxyapatite/chitosan (HA/CS) composites disk from crack in aquous solution, steam treatment was used to improve the crack-resistance of HA/CS disk. The XRD, FTIR and SEM methods were employed to characterize the crystal component, chemical composition and morphology of fracture surface of the composites. The effects of temperature and processing time on water- resistance of HA/CS disk in water were investigated. Results indicate that water steam treatment can facilitate the formation of hydrogen bond and complexation between the ions in HA and the groups of -NH2 , -OH in CS. Thus the crack of HA/CS composites disk is avoided and the water-resistance of the composites is also improved. Temperature or water steam pressure are the main factors affecting the crack of HA/CS disks in water.
参考文献
| [1] | 杜江华.羟基磷灰石/生物高分子复合材料的制备方法进展[J].中国组织工程研究与临床康复,2010(25):4717-4720. |
| [2] | 孟德营,刘金华,姜丽娜.羟基磷灰石/壳聚糖生物复合材料研究进展[J].山东轻工业学院学报（自然科学版）,2009(01):33-37. |
| [3] | 郭恩言,王峰,赵萍,储新宏,姜倩.纳米羟基磷灰石/壳聚糖复合材料的制备及发展趋势[J].中国组织工程研究与临床康复,2010(03):500-504. |
| [4] | 孔祥烨,郑静,王晓军,李星熠,傅少志,李沐纯,钱志勇.壳聚糖在组织工程中的应用[J].中国医学工程,2009(03):185-188. |
| [5] | 胡晓兰,谢鹏辉,王雯皓,余荣禄,申丙星,董炎明.原位增强羟基磷灰石/壳聚糖复合棒材[J].复合材料学报,2011(02):123-129. |
| [6] | 孙珍珍,蔡汝汝,蒲曦鸣,杨云,姚清清,侯振清,张其清.壳聚糖/羟基磷灰石复合骨折内固定棒材的制备与性能研究[J].功能材料,2011(01):128-131. |
| [7] | 卢晓英,王秀红,屈树新,翁杰.纳米羟基磷灰石/壳聚糖杂化材料的制备[J].无机材料学报,2008(02):332-336. |
| [8] | 张利,李玉宝,杨爱萍,左奕,吕国玉,魏杰.骨组织工程用纳米羟基磷灰石/ 壳聚糖多孔支架材料的制备及性能表征[J].功能材料,2005(02):314-317. |
| [9] | 李红,朱敏鹰,周长忍.原位水化法制备羟基磷灰石/壳聚糖复合支架材料[J].功能材料,2010(02):256-259. |
| [10] | 杨菊林,周长忍,田冶,田金环.壳聚糖/羟基磷灰石膜的制备及对细胞生长的影响[J].生物医学工程学杂志,2009(03):580-584. |
| [11] | 张利,李玉宝,魏杰,左奕,韩纪梅,吴兰,王学江.纳米羟基磷灰石/壳聚糖复合骨修复材料的共沉淀法制备及其性能表征[J].功能材料,2005(03):441-444. |
| [12] | 夏傲,苗鸿雁,韩蕾,樊蕃.水热法合成羟基磷灰石晶须[J].无机盐工业,2006(07):33-34. |
| [13] | 高家诚,陈飞宏,张敏.pH值对水热合成HA晶须形貌的影响[J].功能材料,2010(08):1447-1449. |
| [14] | Yamaguchi I;Toduchi K;Fukuzadi H et al.Preparation and mechanical properties of chitosan/hydroxyapatite nanocomposites[J].Materials,2001,673:192-195. |
| [15] | Li Wang;Chunzhong Li .Preparation and physicochemical properties of a novel hydroxyapatite/chitosan-silk fibroin composite[J].Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides,2007(4):740-745. |
| [16] | 蒋挺大.壳聚糖[M].北京:化学工业出版社,2006:20-26. |
| [17] | 卢晓英,王秀红,刘治,翁杰.反应pH值对原位水热沉积法制备纳米羟基磷灰石/壳聚糖复合材料的影响[J].复合材料学报,2009(04):53-58. |
| [18] | 赵营刚,王迎军,卢玲,陈晓峰,吴刚.仿生型壳聚糖-明胶/溶胶凝胶生物玻璃复合支架的制备及其矿化性能研究[J].硅酸盐通报,2006(02):8-11,22. |
| [19] | 夏朝红,戴奇,房韦,陈和生.几种多糖的红外光谱研究[J].武汉理工大学学报,2007(01):45-47. |
| [20] | 蔡日强 .板条状羟基磷灰石及其复合材料的制备和结构性能表征[D].咸阳:陕西科技大学,2010. |
| [21] | 张华亮,王文良,关静,刘英杰,初殿伟,张西正.双层壳聚糖/羟基磷灰石复合支架的制备及性能研究[J].医疗卫生装备,2008(09):4-6,11. |
| [22] | Yamaguchi I;Itoh S;Suzuki M;Osaka A;Tanaka J .The chitosan prepared from crab tendons: II. The chitosan/apatite composites and their application to nerve regeneration.[J].Biomaterials,2003(19):3285-3292. |
| [23] | 张东生,郭领军,李贺军,郭琛,李克智.TG-CVI C/C复合材料裂纹缺陷成因分析[J].炭素技术,2009(01):26-29. |
| [24] | 冯铁程,刘家臣,李顺,杜海燕.陶瓷裂纹的修复[J].稀有金属材料与工程,2005(z1):421-423. |
| [25] | 杨道媛,王雁,鲁占灵.陶瓷材料裂纹愈合研究进展[J].材料导报,2008(07):22-25,30. |
| [26] | 韦东滨,韩静涛,谢建新,贺毓辛.非金属材料裂纹愈合研究综述[J].材料导报,2000(04):37-40. |
- 下载量()
- 访问量()
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%