系统分析了羟基磷灰石(HA)的制备方法和丝素蛋白纤维(SF)的溶解方法,提出一种制备纳米丝素蛋白/羟基磷灰石生物复合材料(SF/HA)的新型反应复合方法--"一步法".并对由"一步法"制得的SF/HA分别进行了钙磷比测定、红外光谱测试、透射电镜观察和x射线衍射测试.结果表明:SF/HA中的钙磷比是1.6692,与标准HA中的钙磷比1.67一致;SF/HA中同时含有SF和HA中各自的官能团;SF/HA的晶粒横向尺度小于100nm,SF/HA呈针状或柱状晶粒,SF和HA能够形成复合;SF/HA的晶型属于六方晶系,当SF在SF/HA中所占质量分数为10%时,晶胞参数a=b=9.0319(A),c=7.0148(A),沿c轴方向平均品粒尺寸是230.7645(A)."一步法"制备SF/HA具有合理性和可行性.
参考文献
[1] | 姚秀敏,谭寿洪,江东亮,多孔羟基磷灰石陶瓷的制备[J].无机材料学报,2000,15(3):468-472.Yao Xiumin,Tan Shonhong,Jiang Dongliang.Preparation of porous hydroxyapatite ceramics[J].Journal of Inorganic Materials,2000,15(3):468-472. |
[2] | Suchanek W,Yoshimura M.Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implants[J].Mater Res,1998,13(1):94-117. |
[3] | Crane G M,Ishaug S L,Mikos A G.Bone tissue engineering[J].Nat Med,1995,12(1):1322. |
[4] | 张阳德,赵梓屹,羟基磷灰石/聚合物复合材料的研究进展[J].中国医学工程,2005,13(6):603-608.Zhanag Yangde,Zhao Ziyi.Progress of hydroxyapatite/polymeric materials composites[J].China Medical Engineering,2005,13(6):603-608. |
[5] | 卢神州,李明忠,白伦,羟基磷灰石/丝素蛋白纳米复合颗粒的制备[J].丝绸,2006,17(2):17-19.Lu Shenzhou,Li Mingzhong,Bai Lun.Fabrication of hydroxyapatite and silk fibroin nanometer complex powders[J].Silk Monthly,2006,17(2):17-19. |
[6] | 杨辉,张林,张宏,徐可为,丝索蛋白/羟基磷灰石复合材料的制备及性能表征[J].复合材料学报,2007,24(3):141-146.Yang Hui,Zhang Lin,Zhang Hong,Xu Kewei.Preparation and characterization of the silk fibroin/hydroxyapatite composites[J].Acta Materiae Cmpositae Sinica,2007,24(3):141-146. |
[7] | 刘佳佳,李明忠,卢神州,羟基磷灰石/丝索蛋白复合材料的制备[J].高分子材料科学与工程,2006,24(5):245-248.Liu Jiajia,Li Mingzhong,Lu Shenzhou.Preparation of HA/SF composite[J].Polymer Materials Science and Engineering,2006,24(5):245-248. |
[8] | 陈国强,鲐素溶解性与再生膜结构的研究[J].苏州丝绸工学院学报,1986(2):45-52.Chen Guoqiang.A Study on the solubility of silk fibroin and the structure of the regenerated fibroin film[J].Journal of Suzhou Institute of Silk Textile Technology,1986(2):45-52. |
[9] | 王志锋,宋邦才,张军,化学分析法精确测定羟基磷灰石中的Ca和P含量[J].硅酸盐通报,2007,26(1):186-189.Wang Zhifeng,Song Bangcai,Zhang Jun.Precise measurement of Ca and P content in hydroxyapatite by chemical analysis[J].Bulletin of the Chinese Ceramic Society,2007,26(1):186-189. |
[10] | 刘粤惠,刘平安,X射线衍射分析原理与应用[M].北京:化学工业出版社,2003:216-220. |
[11] | 马礼敦,近代X射线多晶体衍射--实验技术与数据分析[M].北京:化学工业出版社,2004:16-90. |
[12] | Pretsch E,Buhlmann P,Affolter C.波谱数据表-有机化合物的结构解析[M].荣国斌,译,上海:华东理工大学出版社,2002:245-309. |
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