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形状记忆高分子材料(SMPs)作为一种新型功能材料具有生物相容性好、形变率大、形变温度可调、易于加工、可引人生物降解组分等特点,近年来,特别是在生物医药领域,SMPs已成为研究人员广泛关注的焦点之一。根据SMPs的功能及其应用研究现状,着重综述了近年来SMPs在矫形固定材料、药物缓释体系、手术缝合、微创医疗器械以及组织工程等生物医学领域的主要研究和应用,并展望了SMPs在生物医学领域未来的研究方向和前景,同时,简要介绍了SMPs的发展概况及其具有形状记忆效应的原理。

As a kind of "smart" functional material, shape memory polymers (SMPs) have good biocompatibility, large deformation ratio, adjustable range of deformation temperature, easy processing, and possible biological degradability, and they have drawn much great attention in the field of biomedical research and application in recent years. The research and application of SMPs in biomedical field are reviewed, for example, in orthopaedic fixed materials, drug release system, surgical equipment, suture and tissue engineering. Further perspectives are discussed for SMPs, and their research progress and relevant mechanism are briefly introduced meanwhile.

参考文献

[1] 朱光明.S形状记忆聚合物及其应用[M].,2002
[2] 李世缙;张蔚盛.原子辐射与聚合物[M].Shanghai:ShanghaiScienceandTechnologyPress,1963
[3] 赵兴 .储能形状记忆聚氨酯的合成与表征[D].天津工业大学,2006.
[4] Jinsong Leng .Shape-Memory Polymers-A Class of Novel Smart Materials[J].MRS bulletin,2009(11):848-855.
[5] Ratna, D.;Karger-Kocsis, J. .Recent advances in shape memory polymers and composites: A review[J].Journal of Materials Science,2008(1):254-269.
[6] 潘道成;张和庚;张隐西.形状记忆聚合物的原理和应用[J].化学世界,1990(12):584-587.
[7] 蔡伟;鲁玺丽;赵连城.聚L一乳酸作为医用形状记忆材料的新用途[M].,2004
[8] 形状记忆聚合物及其在生物医学工程中的应用[J].生物医学工程学杂志,2005(05):1082-1084.
[9] 马跃宇.由可再吸收的形状记忆聚合物制作的移植骨骼[J].现代材料动态,2010(10):12-13.
[10] Yong Chae Jung;Jae Whan Cho .Application of shape memory polyurethane in orthodontic[J].Journal of Materials Science. Materials in Medicine,2010(10):2881-2886.
[11] 刘丽莉.可生物降解的PGS和PGGS的微观结构与形状记忆效应[M].,2009
[12] 戴亚妮,李平,王爱勤.智能高分子材料在智能给药系统中的应用[J].化学进展,2007(02):362-369.
[13] Wischke, C;Neffe, AT;Steuer, S;Lendlein, A .Evaluation of a degradable shape-memory polymer network as matrix for controlled drug release[J].Journal of Controlled Release: Official Journal of the Controlled Release Society,2009(3):243-250.
[14] Armin Alteheld;Yakai Feng;Steffen Kelch;Andreas Lendlein .Biodegradable,Amorphous Copolyester-Urethane Networks Having Shape-Memory Properties[J].Angewandte Chemie,2005(8):1188-1192.
[15] M. Conception Serrano;Luis Carbajal;Guillermo A. Ameer .Novel Biodegradable Shape-Memory Elastomers with Drug-Releasing Capabilities[J].Advanced Materials,2011(19):2211-2215.
[16] 刘青;王彭延 .国外医用缝合线的发展概况[J].国外医学(生物医学工程分册),1993,16(06):324-328.
[17] Lendlein A;Langer R .Biodegradable, elastic shape-memory polymers for potential biomedical applications[J].Science,2002(5573):1673-1676.
[18] 冷劲松;刘彦菊;吴雪莲 .生物可降解的形状记忆缝合线[P].China,1013323IOA,2008-12-31.
[19] Goraltchouk A;Lai J;Herrmann R A et al.Shape Memory Self- Retaining Sutures,Methods of Manufacture,and Methods of U.~e[P].US,0125188A1,2011-03-26.
[20] Metzger M F;Wilson T S;Schumann D et al.Mechanical Prop- erties of Mechanical Actuator for Treating Ischemic Stroke[J].Biomedical Microdevices,2002,4(02):89-96.
[21] Maitland DuncanJ;Metzger MelodieF;Schumann Daniel;Lee Abraham;Wilson ThomasS .Photothermal properties of shape memory polymer micro-actuators for treating stroke.[J].Lasers in surgery and medicine,2002(1):1-11.
[22] Ortega J;Maitland D;Wilson T;Tsai W;Savas O;Saloner D .Vascular dynamics of a shape memory polymer foam aneurysm treatment technique.[J].Annals of Biomedical Engineering: The Journal of the Biomedical Engineering Society,2007(11):1870-1884.
[23] 李永刚 .具有形状记忆功能的D,L一聚乳酸基输卵管避孕材料的制备与研究[D].,2009.
[24] Andreas Lendlein Marc Behl Bernhard Hiebl Christian Wischke .Shape-memory polymers as a technology platform for biomedical applications[J].Expert review of medical devices,2010(3):357-379.
[25] Sundback CA;Shyu JY;Wang YD;Faquin WC;Langer RS;Vacanti JP;Hadlock TA .Biocompatibility analysis of poly(glycerol sebacate) as a nerve guide material[J].Biomaterials,2005(27):5454-5464.
[26] 罗彦凤,刘钊,李永刚,王远亮.人脐静脉内皮细胞在D,L-聚乳酸基形状记忆聚合物上的黏附和增殖行为研究[J].中国生物工程杂志,2010(05):1-5.
[27] Qinghao Meng;Jinlian Hu .A review of shape memory polymer composites and blends[J].Composites. Part A, Applied science and manufacturing,2009(11):1661-1672.
[28] Shenoy DK.;Thomsen DL.;Srinivasan A.;Keller P.;Ratna BR. .Carbon coated liquid crystal elastomer film for artificial muscle applications[J].Sensors and Actuators, A. Physical,2002(2/3):184-188.
[29] Donald L. Thomsen III;Patrick Keller;Jawad Naciri;Roger Pink;Hong Jeon;Devanand Shenoy;Banahalli R. Ratna .Liquid Crystal Elastomers with Mechanical Properties of a Muscle[J].Macromolecules,2001(17):5868-5875.
[30] Properties and mechanism of two-way shape memory polyurethane composites[J].Composites science and technology,2010(10):P.1437.
[31] Zotzmann J;Behl M;Hofmann D et al.Reversible Triple-Shape Effect of Polymer Networks Containing Polypentadecalactone-and Poly(Epsilon-Caprolactone)-Segments[J].Advanced Materials,2010,22(31):3424-3429.
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