磁性纳米颗粒作为非病毒基因载体介导的基因转染(即磁性转染)是基因治疗中极具运用前景的技术之一.主要介绍了磁性纳米颗粒的种类和性质,介导基因转染的最新研究进展,在细胞内的定位和动态过程,面临的问题以及将来的发展前景.
参考文献
| [1] | Bertram J .[J].Current Pharmaceutical Biotechnology,2006,7(04):277-285. |
| [2] | Dobson J .Gene therapy progress and prospects: magnetic nanoparticle-based gene delivery.[J].Gene therapy,2006(4):283-287. |
| [3] | Hadjipanayis G C;Siegel R W.Nanophase Materials:Synthesis,Properties and Applications (NATO Science Series E:Applied Sciences,Volume 260)[M].Netherland:Kluwer Academic,1994 |
| [4] | 廖鹏飞,夏金兰,聂珍媛,谢建平.磁性微球的制备及在生物分离应用中的研究进展[J].生物磁学,2005(04):47-51. |
| [5] | 钱斯日古楞,王红英.磁性淀粉复合微球的制备及其性质[J].大连轻工业学院学报,2003(03):191-193. |
| [6] | Risoen PA.;Myrset AH.;Gabrielsen OS.;Struksnes K. .ONE-STEP MAGNETIC PURIFICATION OF RECOMBINANT DNA-BINDING PROTEINS USING MAGNETIZABLE PHOSPHOCELLULOSE[J].Protein Expression and Purification,1995(3):272-277. |
| [7] | 常津 .[J].中国生物医学工程学报,1996,15(04):378-381. |
| [8] | Baki D E;Ebru K;Cengiz B et al.[J].Reactive and Functional Polymers,2002,50(03):225-232. |
| [9] | 张晓金,原续波,胡云霞,常津,康春生,浦佩玉.具有靶向抗癌功能的O-CMC磁性纳米载体系统的制备[J].高分子通报,2004(03):89-92,98. |
| [10] | Chang Yang;Chen Dong .[J].Journal of Colloid and Interface Science,2005,283:446-451. |
| [11] | 邱广亮,栗淑媛,金志兰,刘春艳.磁性琼脂糖复合微球的制备和性质[J].精细化工,1999(01):38-40. |
| [12] | 邱广亮;邱广明 .[J].食品科学,1998,19(11):7-11. |
| [13] | Ghassabian S;Ehtezazi T;Forutan S M et al.[J].International Journal of Pharmaceutics,1996,130:49-55. |
| [14] | Denizot B;Tanguy G;Hindre F et al.[J].Journal of Colloid and Interface Science,1999,209(01):66-71. |
| [15] | Gupta A K;Wells S .[J].IEEE TRANSACTIONS IN NANOBIOSCIENCE,2004,3(01):66-73. |
| [16] | Guo-bin Shan;Jian-min Xing;Ming-fang Luo;Hui-zhou Liu;Jia-yong Chen .Immobilization of Pseudomonas delafieldii with magnetic polyvinyl alcohol beads and its application in biodesulfurization[J].Biotechnology Letters,2003(23):1977-1981. |
| [17] | Liao Minhung;Chen Donghwang .[J].Biotechnology Letters,2002,24:1913-1917. |
| [18] | Zheng Weiming;Gao Feng;Gu Hongchen .[J].Journal of Magnetism and Magnetic Materials,2005,288:403-410. |
| [19] | Zhongbing Huang;Fangqiong Tang .Preparation,structure,and magnetic properties of polystyrene coated by Fe_3O_4 nanoparticles[J].Journal of Colloid and Interface Science,2004(1):142-147. |
| [20] | 王德平,娄敏毅,黄文旵,赵慧君.偶联剂修饰纳米磁性粒子红外光谱及相关分析[J].同济大学学报(自然科学版),2005(02):201-204,229. |
| [21] | Iwata A;Murata M;Hikata M;Hayakawa T;Yamaguchi T .Virus concentration using polyethyleneimine-conjugated magnetic beads for improving the sensitivity of nucleic acid amplification tests[J].Journal of Virological Methods,2003(1):11-19. |
| [22] | Kevin L. Klug;Vinayak P. Dravid;D. Lynn Johnson .Silica-encapsulated magnetic nanoparticles formed by a combined arc evaporation/chemical vapor deposition technique[J].Journal of Materials Research,2003(4):988-993. |
| [23] | Jun Lin;Weilie Zhou;A.Kumbhar;J.Wiemann;Jiye Fang;E.E.Carpenter;C.J.O'Connor .Gold-Coated Iron (Fe@Au) Nanoparaticles: Synthesis, Characterization, and Magnetic Field-Induced Self-Assembly[J].International Journal of Quantum Chemistry,2001(1):26-31. |
| [24] | 唐秋莎,张东生,顾宁,丛小明,万美玲,金立强.新型纳米基因载体（PEI/Mn0.5Zn0.5Fe2O4）的制备、表征及体外实验[J].功能材料,2007(08):1268-1272. |
| [25] | 向娟娟,朱诗国,吕红斌,阮建明,张必成,李江,李桂源.用氧化铁磁性纳米颗粒作为基因载体的研究[J].癌症,2001(10):1009-1014. |
| [26] | Xiang Juanjuan;Tang Jingqun;Zhu Shiguo et al.[J].Journal of Gene Medicine,2003,5:803-817. |
| [27] | Dash PR;Read ML;Barrett LB;Wolfert MA;Seymour LW .Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery.[J].Gene therapy,1999(4):643-650. |
| [28] | Stephanie R;Hagen B;Helga R W et al.[J].Control Release,2003,92:199. |
| [29] | He X X;Wang K M;Tan W H et al.[J].Journal of the American Chemical Society,2003,125:7168. |
| [30] | 庄乾元,孙璇,周四维,管维,叶章群.葡聚糖磁性纳米颗粒在基因转染中的应用[J].武汉大学学报(医学版),2007(03):270-273,286,封2. |
| [31] | Gersting S W;Schillinger U;Lausier J et al.[J].Journal of Gene Medicine,2004,6:913-922. |
| [32] | Dobson J;Smith M;Farrow N .[J].European Cells and Materials,2008,16(03):49. |
| [33] | Dobson J;McBain S C;Farrow N et al.[J].European Cells and Materials,2008,16(03):48. |
| [34] | Bergemann C;Mullar-sehulte D et al.[J].Journal of Magnetism and Magnetic Materials,1999,194:45-52. |
| [35] | Mykhaylyk O;Vlaskou D;Tresilwised N;Pithayanukul P;Moller W;Plank C .Magnetic nanoparticle formulations for DNA and siRNA delivery[J].Journal of Magnetism and Magnetic Materials,2007(1):275-281. |
| [36] | 曹正国,孙友文,诸禹平,苏红,吴斌,刘继红,周四维.磁性小干扰RNA纳米微粒的制备及其转染人膀胱癌细胞对沉默survivin基因表达影响的研究[J].中国现代医学杂志,2008(04):385-390. |
| [37] | Grief AD;Richardson G .Mathematical modelling of magnetically targeted drug delivery[J].Journal of Magnetism and Magnetic Materials,2005(1):455-463. |
| [38] | Plank C;Scherer F et al.[J].European Cells and Materials,2002,2(03):79-80. |
| [39] | Prow T;Smith J N;Grebe R et al.[J].Molecular Vision,2006,12:606-615. |
| [40] | Yang S Y;Sun J S;Liu C H .[J].Artificial Organs,2007,32(03):195-204. |
| [41] | Morishita, N;Nakagami, H;Morishita, R;Takeda, S;Mishima, F;Terazono, B;Nishijima, S;Kaneda, Y;Tanaka, N .Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector[J].Biochemical and Biophysical Research Communications,2005(4):1121-1126. |
| [42] | Luo,D;Saltzman,WM .Synthetic DNA delivery systems.[J].Nature biotechnology,2000(1):33-37. |
| [43] | Sauer A M;de Bruin K G et al.[J].Abstracts/Journal of Controlled Release,2008,132:e15-e16. |
| [44] | de-Bruin K;Ruthardt N;von-Gersdorff K;Bausinger R;Wagner E;Ogris M;Brauchle C .Cellular dynamics of EGF receptor-targeted synthetic viruses.[J].Molecular therapy: the journal of the American Society of Gene Therapy,2007(7):1297-1305. |
| [45] | 吴乃虎.基因工程原理[M].北京:科学出版社,2003 |
| [46] | 王关林;方宏筠.植物基因工程[M].北京:科学出版社,2002 |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%