研究了具有良好血液相容性的磷脂聚乳酸用异氰酸酯扩链的反应.核磁共振(1H-NMR)和红外光谱(FT-IR)结果证明扩链反应是成功的.凝胶渗透色谱(GPC)测定分子量的结果显示,磷脂聚乳酸的(M)n.在扩链后增加约一倍,改变扩链反应条件,扩链磷脂聚乳酸的(M)n增加倍率变化不大;纯聚乳酸扩链后(M)n增加约十倍,但纯聚乳酸在扩链反应中更容易发生交联.研究结果表明,磷脂聚乳酸的扩链反应增加分子量约一倍是由其分子结构决定的.
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