通过冷压和固化技术成功的制备了PLGA-HA-TiO2复合材料,并考察了其机械性能和在模拟体液中的降解速率,采用扫描电子显微镜观察了其显微组织.结果表明,当复合材料中含25%(质量分数)的HA和2.5%(质量分数)的TiO2时,复合材料具有好的强度和塑性.HA含量少于50%(质量分数)时,对其在模拟体液中的降解速率基本没影响;反之,其降解速率会增加.在降解过程中,PLGA-HA-TiO2的表面形成磷灰石,表明该复合材料具有好的生物相容性.
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