蒙脱石作为药用辅料及药物载体的研究进展

硅酸盐通报 , 2013, 32(3): 414-418.

蒙脱石作为药用辅料及药物载体的研究进展

邓春兰 ^1, , 于明安 ^2, , 王馨 ^3, , 廖一兰 ^4,

1.重钢总医院药剂科,重庆400081

2.重庆医科大学药学院药物化学教研室,重庆400016

3.重钢总医院药剂科,重庆400081

4.重钢总医院药剂科,重庆400081

关键词：蒙脱石 , 药用辅料 , 药物载体

Research Progress of Montmorillonite as Pharmaceutical Excipients and Drug Carriers

本文介绍了蒙脱石作为药用辅料在助悬剂、崩解剂、粘合剂、稳定剂、吸附剂、抗菌剂等方面的研究现状,综述了蒙脱石作为药物载体应用于医药领域的国内外最新研究进展.

参考文献

[1]	P. Canizares;A. Duran;F. Dorado .The role of sodium montmorillonite on bounded zeolite-type catalysts[J].Applied clay science,2000(5/6):273-287.
[2]	Viseras C;Meeten GH;Lopez Galindo-A .Pharmaceutical grade phyllosilicate dispersions: the influence of shear history on floc structure.[J].International Journal of Pharmaceutics,1999(1):7-20.
[3]	Lee YH;Chen BY;Lin KY;Lin KF;Lin FH .Feasibility study of using montmorillonite for stability enhancement of L-ascorbic acid[J].Journal of the Chinese Institute of Chemical Engineers,2008(3):219-226.
[4]	O. Abollino;M. Aceto;M. Malandrino;C. Sarzanini;E. Mentasti .Adsorption of heavy metals on Na-montmorillonite. Effect of pH and organic substances[J].Water research: A journal of the international water association,2003(7):1619-1627.
[5]	Cai Y;Meng XF;Cao YX;Lu H;Zhu SF;Zhou LZ .Montmorillonite ameliorates hyperthyroidism of rats and mice attributed to its adsorptive effect.[J].European Journal of Pharmacology: An International Journal,2006(1/3):156-161.
[6]	李国平,吕英海,周仕学,曹智琨.蒙脱石对蛋白质吸附行为的研究[J].硅酸盐通报,2010(04):834-837,851.
[7]	赵兵,武昕,王国清.载银蒙脱石无机抗菌剂的抗菌性能研究[J].硅酸盐通报,2009(05):951-954.
[8]	叶瑛,周玉航,夏枚生,胡彩虹,凌洪飞.新型无机抗菌材料：载铜蒙脱石及其抗菌机理讨论[J].无机材料学报,2003(03):569-574.
[9]	Hu CH;Xu ZR;Xia MS .Antibacterial effect of Cu2+-exchanged montmorillonite on Aeromonas hydrophila and discussion on its mechanism[J].Veterinary microbiology,2005(1/2):83-88.
[10]	Park JK;Choy YB;Oh JM;Kim JY;Hwang SJ;Choy JH .Controlled release of donepezil intercalated in smectite clays.[J].International Journal of Pharmaceutics,2008(1/2):198-204.
[11]	Hasmukh A. Patel;Sunil Shah;Dinesh O. Shah;PA Joshi .Sustained release of venlafaxine from venlafaxine-montmorillonite-polyvinylpyrrolidone composites[J].Applied clay science,2011(1/2):126-130.
[12]	Tramadol hydrochloride/montmorillonite composite: Preparation and controlled drug release[J].Applied clay science,2010(3):108-112.
[13]	Lin FH;Lee YH;Jian CH;Wong JM;Shieh MJ;Wang CY .A study of purified montmorillonite intercalated with 5-fluorouracil as drug carrier.[J].Biomaterials,2002(9):1981-1987.
[14]	Li, Z.;Chang, P.-H.;Jean, J.-S.;Jiang, W.-T.;Hong, H. .Mechanism of chlorpheniramine adsorption on Ca-montmorillonite[J].Colloids and Surfaces, A. Physicochemical and Engineering Aspects,2011(1/3):213-218.
[15]	Joshi GV;Kevadiya BD;Bajaj HC .Controlled release formulation of ranitidine-containing montmorillonite and Eudragit E-100.[J].Drug development and industrial pharmacy,2010(9):1046-1053.
[16]	Synthesis and antifungal activities of polymer/montmorillonite-terbinafine hydrochloride nanocomposite films[J].Applied clay science,2009(2):136-140.
[17]	Giora Rytwo;Hilla Varman;Nir Bluvshtein;Tom N. Konig;Asaf Mendelovits;Amir Sandier .Adsorption of berberine on commercial minerals[J].Applied clay science,2011(1/2):43-50.
[18]	Shuibo Hua;Huixia Yang;Wenbo Wang;Aiqin Wang .Controlled release of ofloxacin from chitosan-montmorillonite hydrogel[J].Applied clay science,2010(1):112-117.
[19]	Rajashree Nanda;Abhisek Sasmal;P.L. Nayak .Preparation and characterization of chitosan-polylactide composites blended with Cloisite 30B for control release of the anticancer drug paclitaxel[J].Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides,2011(2):988-994.
[20]	Kevadiya BD;Joshi GV;Patel HA;Ingole PG;Mody HM;Bajaj HC .Montmorillonite-alginate nanocomposites as a drug delivery system: intercalation and in vitro release of vitamin B1 and vitamin B6.[J].Journal of biomaterials applications,2010(2):161-177.
[21]	Kevadiya BD;Joshi GV;Bajaj HC .Layered bionanocomposites as carrier for procainamide.[J].International Journal of Pharmaceutics,2010(1/2):280-286.
[22]	Dong YC;Feng SS .Poly(D,L-lactide-co-glycolide)/montmorillonite nanoparticles for oral delivery of anticancer drugs[J].Biomaterials,2005(30):6068-6076.
[23]	Campbell K;Craig DQ;McNally T .Poly(ethylene glycol) layered silicate nanocomposites for retarded drug release prepared by hot-melt extrusion.[J].International Journal of Pharmaceutics,2008(1/2):126-131.

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蒙脱石作为药用辅料及药物载体的研究进展

Research Progress of Montmorillonite as Pharmaceutical Excipients and Drug Carriers

参考文献