采用溶剂辅助原位分散方法,制备纳米二氧化硅(nano-SiO2)/聚(癸二酸-甘油-柠檬酸)酯(PGSC)生物弹性体复合材料.通过FTIR、SEM、广角X射线衍射(WXRD)、DSC以及力学测试等手段,对复合材料的结构和性能进行了表征.PGSC基体不仅对nano-SiO2产生包覆,还与nano-SiO2之间形成化学结合.随nano-SiO2质量分数增加,其在基体中的分散更精细均匀.nano-SiO2的加入消弱了基体的有序结构,但是无机填料网络的形成则使复合材料的有序结构增强;加入少量nano-SiO2有利于提高基体的玻璃化转变温度(Tg),但加入较多nano-SiO2时,Tg反而降低.复合材料具有优良的回弹性,其拉伸强度和模量随nano-SiO2质量分数的增加而提高;当质量分数为16.67%时,强度和模量分别提高了602.20%和258.21%.
参考文献
| [1] | Lee S D,Hsiue G H,Chang P C T,et al.Plasma-induced grafted polymerization of acrylic acid and subsequent grafting of collagen onto polymer film as biomaterials[J].Biomaterials,1996,17(16):1599-1608. |
| [2] | Wang Y D,Ameer G A,Sheppard B J,et al.A tough biodegradable elastomer[J].Nature Biotechnology,2002,20 (6):602-606. |
| [3] | Wang YD,Kim Y M,Langer R.In vivo degradation characteristics of poly(glycerol sebacate)[J].Journal of Biomedical Materials Research Part A,2003,66(1):192-197. |
| [4] | Ifkovits J L,Padera R F,Burdick J A.Biodegradable and radically polymerized elastomers with enhanced processing capabilities[J/OL].Biomedical Materials,2008,3(3):034104.http://iopscience.iop.org/1748-605X/3/3/034104. |
| [5] | Nijst C L E,Bruggeman J P,Karp J M,et al.Synthesis and characterization of photocurable elastomers from poly(glycerol-cosebaeate)[J].Biomacromolecules,2007,8(10):3067-3073. |
| [6] | Yang J,Webb A R,Ameer G A.Nobel citric acid-based biodegradable elastomers for tissue engineering[J].Advanced Materials,2004,16(6):511-516. |
| [7] | Yang J,Webb A R,Pickerill S J,et al.Synthesis and evaluation of poly(diol citrate) biodegradable elastomers[J].Biomaterials,2006,27(9):1889-1898. |
| [8] | Younes H M,Bravo-Grimaldo E,Amsden B G.Synthesis,characterization and in vitro degradation of a biodegradable elastomer[J].Biomaterials,2004,25(22):5261-5269. |
| [9] | Amsden B,Wang S,Wyss U.Synthesis and characterization of thermoset biodegradable elastomers based on star-poly(e caprolactone-co-D,L-laetide)[J].Biomaeromolecules,2004,5(4):1399-1404. |
| [10] | Amsden B G,Misra G,Gu F,et al.Synthesis and characterization of a photo-crosslinked biodegradable elastomer[J].Biomacromolecules,2004,5(6):2479-2486. |
| [11] | Storey R F,Warren S C,Allison C J,et al.Methacrylate-endcapped poly (D,L-lactide-co-trimethylene carbonate)oligomers:Network formation by thermal free-radical curing[J].Polymer,1997,38(26):6295-6301. |
| [12] | Zhang Z,Grijpma D W,Feijen J.Triblock eopolymers based on 1,3-trimethylene carbonate and lactide as biodegradable thermoplastic elastomers[J].Macromoleeular Chemistry and Physics,2004,205(7):867-875. |
| [13] | Nagata M,Tanabe T,Sakai W,et al.Preparation and properties of biodegradable network poly (ester-carbonate)elastomers[J].Polymer,2008,49(6):1506-1511. |
| [14] | Djordjevic I,Choudhury N R,Dutta N K,et al.Synthesis and characterization of novel citric acid-based polyester elastomers[J].Polymer,2009,50(7/:1682-1691. |
| [15] | Sundback C A,Shyu J Y,Wang Y D,et al.Biocompatibility analysis of poly(glyccrol sebacate) as a nerve guide material[J].Biomaterials,2005,26(27):5454-5464. |
| [16] | Kang Y,Yang J,Khan S,et al.A new biodegradable polyester elastomer for cartilage tissue engineering[J].Journal of Biomedical Materials Research Part A,2006,77(2):331-339. |
| [17] | Wada R,Hyon S H,Nakamura T,et al.In vitro evaluation of sustained drug release from biodegradable elastomer[J].Pharmaceutical Research,1991,8(10):1292-1296. |
| [18] | Amsden B G.Biodegradable elastomers in drug delivery[J].Expert Opinion on Drug Delivery,2008,5(2):175-187. |
| [19] | Liu Q Y,Tian M,Ding T,et al.Preparation and characterization of a biodegradable polyester elastomer with thermal processing abilities[J].Journal of Applied Polymer Science,2005,98 (5):2033-2041. |
| [20] | Liu Q Y,Tian M,Ding T,et al.Preparation and characterization of a thermoplastic poly(glycerol-sebacate) elastomer by two-step method[J].Journal of Applied Polymer Science,2007,103(3):1412-1419. |
| [21] | Liu Q Y,Tian M,Shi R,et al.Structure and properties of thermoplastic poly (glycerol-sebacate) elastomers originating from prepolymers with different molecular weights[J].Journal of Applied Polymer Science,2007,104 (2):1131-1137. |
| [22] | Lei L J,Ding T,Shi R,et al.Synthesis,characterization and in vitro degradation of a novel degradable poly((1,2-propanediolsebacate)-citrate) bioelastomer[J].Polymer Degradation and Stability,2007,92(3):389-396. |
| [23] | Liu Q Y,Wu S Z0 Tan T W,et al.Preparation and properties of a novel biodegradable polyester elastomer with functional Cgroups[J].Journal of Biomaterials Science:Polymer Edition,2009,20(11):1567-1578. |
| [24] | Liu QY,Tan T W,Weng J Y,et al.Study on the control of the compositions and properties of a biodegradable polyester elastomer[J/OL].Biomedical Materials,2009,4 (2):025015.http://iopscience.iop.org/1748-605X/4/2/025015. |
| [25] | 张立群,吴友平,王益庆,等.橡胶的纳米增强及纳米复合技术[J].合成橡胶工业,2000,23(2):71-77.Zhang Liqun,Wu Youping,Wang Yiqing,et al.The nanoreinforcing and nano-compounding technique of rubber[J].China Synthetic Rubber Industry,2000,23(2):71-77. |
| [26] | 李丽,雷丽娟,吴珺玥,等.可生物降解纳米羟基磷灰石/聚酯型弹性体复合材料的制备及性能[J].复合材料学报,2009,26(5):60-67.Li Li,Lei Lijuan,Wu Junyue,et al.Preparation and investigation of a biodegradable nano-hydroxyapatite/polyester elastomer composites[J].Acta Materiae Compositae Sinica,2009,26(5):60-67. |
| [27] | Liu Q Y,Wu J Y,Tan T W,et al.Preparation,properties and cytotoxieity evaluation of a biodegradable polyester elastomer composite[J].Polymer Degradation and Stability,2009,94(9):1427-1435. |
| [28] | Heinemann S,Heinemann C,Bernhardt R,et al.Bioactive silica-collagen composite xerogets modified by calcium phosphate phases with adjustable mechanical properties for bone replacement[J].Acta Biomaterialia,2009,5(67:1979-1990. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%