淀粉基(starch-based)材料是一类重要的生物降解聚合物,羟基磷灰石(HA)是人体骨骼的主要成分,以淀粉基材料为基体、以HA为增强材料的HA/淀粉基复合材料是一类新型的复合生物材料,其具有良好的生物相容性,在骨修复领域具有巨大的应用潜力.初步对该复合材料进行了归类,并介绍了其制备工艺、性能和应用等方面的研究近况,指出改进复合工艺、采用纳米级HA增强并进行表面改性是其发展趋势.
参考文献
[1] | Lorcks J. .Properties and applications of compostable starch-based plastic material[J].Polymer Degradation and Stability,1998(1/3):245-249. |
[2] | Reis R L;Cunha A M .Starch and starch based thermoplastics[J].Encyclopedia of Material Science and Engineering,2001,10:8810. |
[3] | Reis R L;Cunha A M;Bevis M J.Mechanical behaviour of injection moulded starch based polymers[J].Polymers for Advanced Technologies,1996(07):784. |
[4] | KIM S H;Chin I J;Yoon J S .Mechanical properties of biodegradable blends of poly L-lactic acid and starch[J].Korean Polymer Journal,1998,6:422. |
[5] | Averous L;Boquillon N .Biocomposites based on plasticized starch.thermal and mechanical behavious[J].Carbohydrate Polymers,2004,56:111. |
[6] | Ke TY.;Sun XZ. .Physical properties of poly(lactic acid) and starch composites withvarious blending ratios[J].Cereal Chemistry,2000(6):761-768. |
[7] | Reis R L;Cunha A M.New degradable load-bearing biomaterials based on reinforced thermoplastic starch incorporating blends[J].Journal of Appl Med Polym,2000:1. |
[8] | Demirgoz D.;Mano JF.;Cunha AM.;Piskin E.;Reis RL.;Elvira C. .Chemical modification of starch based biodegradable polymeric blends: effects on water uptake, degradation behaviour and mechanical properties[J].Polymer Degradation and Stability,2000(2):161-170. |
[9] | Araujo M A;Vaz C M;Cunha A M et al.In-vitro degradation behaviour of starch/EVOH biomaterials[J].Polymer Degradation and Stability,2000,73(02):237. |
[10] | Reis R L;Mendes S C;Cunha A M et al.Processing and in-vitro degradation of starch/EVOH thermoplastic blends[J].Polymer International,1997,2(43):347. |
[11] | Mano JF.;Cunha AM.;Reis RL. .Effects of moisture and degradation time over the mechanical dynamical performance of starch-based biomaterials[J].Journal of Applied Polymer Science,2000(13):2345-2357. |
[12] | Araujo MA;Cunha AM;Mota M .Enzymatic degradation of starch-based thermoplastic compounds used in protheses: identification of the degradation products in solution.[J].Biomaterials,2004(13):2687-2693. |
[13] | Helena S.Azevedo;Francisco M.Gama;Rui L.Reis .In Vitro Assessment of the Enzymatic Degradation of Several Starch Based Biomaterials[J].Biomacromolecules,2003(6):1703-1712. |
[14] | Marques AP;Reis RL;Hunt JA .The biocompatibility of novel starch-based polymers and composites: in vitro studies.[J].Biomaterials,2002(6):1471-1478. |
[15] | Sandra C M;Reis R L;Yvonne P B.Biocompatibility testing of novel starch-based materials with potential application in orthopaedic.a preliminary study[J].Biomaterials,2001(22):2057. |
[16] | Gomes ME;Reis RL;Cunha AM;Blitterswijk CA;de-Bruijn JD .Cytocompatibility and response of osteoblastic-like cells to starch-based polymers: effect of several additives and processing conditions.[J].Biomaterials,2001(13):1911-1917. |
[17] | Marques A P;Reis R L;Hunt J A.Evaluation of the potential of starch-based biodegradable polymers in the activation of human inflammatory cells[J].Journal of Materials Science:Materials in Medicine,2003:167. |
[18] | Gomes ME;Ribeiro AS;Malafaya PB;Reis RL;Cunha AM .A new approach based on injection moulding to produce biodegradable starch-based polymeric scaffolds: morphology, mechanical and degradation behaviour.[J].Biomaterials,2001(9):883-889. |
[19] | Gomes M E;Godinho J S;Tchalamov D.Alternative tissue engineering scaffolds based on starch.processing methodologies,morphology,degradation and mechanical properties[J].Materials Science and Engineering C,2002:19. |
[20] | Mano J F;Sousa R A;Boesel L F et al.Bionert,biodegradable and injectable polymeric matric composites for hard tissue replacement.state of the art and recent development[J].Composites Science and Technology,2004,64:789. |
[21] | Pereira CS.;Reis RL.;Vazquez B.;San Roman J.;Cunha AM. .New starch-based thermoplastic hydrogels for use as bone cements or drug-delivery carriers[J].Journal of Materials Science. Materials in Medicine,1998(12):825-833. |
[22] | 戈进杰.生物高分子材料及其应用[M].北京:化学工业出版社,2002:48. |
[23] | 刘榕芳,肖秀峰,林岚云,陈古镛.水热电沉积羟基磷灰石涂层的研究[J].高等学校化学学报,2004(02):304-308. |
[24] | Ismael E;Carlos E;Mano J F.New partially biodegradable and bioactive acrylic bone cements based on starch blends and ceramic fillers[J].Biomaterials,2002(23):1883. |
[25] | Mano J F;Koniarova D;Reis R L.Thermal properities of themroplastic starch/synthetic polymer blends with potential biomedical applicability[J].Journal of Materials Science:Materials in Medicine,2003:127. |
[26] | Sousa R A;Reis R L;Cunha A M et al.Processing and properties of bone-analogue biodegradable and bioinert polymeric composites[J].Composites Science and Technology,2003,63:389. |
[27] | Reis R L;Cunha A M;Michael J B.Using nonconventional processing to develop anisotropic biodegradable composites of starch-based thermoplastics reinforced with bone-like ceramics[J].Medic Plast Biomater,1997:46. |
[28] | Reis R L;CunhaA M;Allan P S et al.Structure development and control of injection-molded hydroxylapatite-reinforced starch/EVOH composites[J].Advances in Polymer Technology,1997,4(16):263. |
[29] | Sousa R A;Mano J F;Reis R L et al.Mechanical performance of starch based bioactive composite biomaterials molded with preferred orientation[J].Polymer Engineering and Science,2002,5:1032. |
[30] | 贾崇明;贾颖.剪切控制取向注射成型概述[J].现代塑料加工应用,1997(06):24. |
[31] | Mano J F;Vaz M;Mendes S C.Dynamical mechanical properties of hydroxylapatite reinforced and porous starch-based degradable biomaterials[J].Journal of Materials Science:Materials in Medicine,1999:857. |
[32] | RODRIGUEZ L M;Mallet R M;Ferreira J M .Fabrication of porous hydroxyapatite bodies by a new direct consolidation method:starch consolidation[J].Journal of Biomedical Materials Research,2002,2:232. |
[33] | Lemos A F;Ferreira J M .Combining foaming and starch consolidation methods to develop macroporous HA implants[J].Key Engineering Materials,2004,6(254):1041. |
[34] | Vaz C. M,;Reis R L;Cunha A M.Improvement of Interfacial Interactions in Starch-EVOH/HA Composites[A].,1999:377. |
[35] | Vaz CM;Reis RL;Cunha AM .Use of coupling agents to enhance the interfacial interactions in starch-EVOH/hydroxylapatite composites.[J].Biomaterials,2002(2):629-635. |
[36] | Leonor IB;Ito A;Onuma K;Kanzaki N;Reis RL .In vitro bioactivity of starch thermoplastic/hydroxyapatite composite biomaterials: an in situ study using atomic force microscopy.[J].Biomaterials,2003(4):579-585. |
[37] | Vaz C M;Reis R L;Cunha A M.Degradation model of starch-EVOH+ HA composites[J].Materials Research Innovations,2001(04):375. |
[38] | 李玉宝.生物医学材料[M].北京:化学工业出版社,2003:265. |
[39] | 傅杰,李世普.生物可降解高分子材料及其在医学领域的应用(Ⅱ)[J].武汉工业大学学报,1999(05):19-22. |
[40] | 柯扬船;皮特·斯壮.聚合物-无机纳米复合材料[M].北京:化学工业出版社,2003:53. |
[41] | 姜永梅,姜萍,翁杰.羟基磷灰石(HA)表面改性对HA/聚乳酸复合材料力学性能的影响[J].功能材料,2004(z1):2424-2426,2430. |
[42] | 朱林杰,耿孝正,马秀清,李鹏.啮合同向双螺杆挤出过程聚合物熔融机理研究--螺纹元件组合中聚合物的熔融[J].中国塑料,2000(04):70-78. |
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