为了改善聚丁二酸丁二醇酯poly-(butylene succinate)一壳聚糖复合材料的表面生物学性能,进行193 nm激光刻蚀该复合材料的研究,以提高该复合材料的表面生物活性.采用表面轮廓仪、表面水接触角分析仪、扫描电镜、红外衰减全反射研究改性后材料表面的特性;并采用DNA分析的方法分析材料表面细胞的生物学特性.研究结果表明,复合材料表面与本体的激光刻蚀能量闻值分别为59 mJ/cm2和125 mJ/cm2.图像定量分析表明随着刻蚀次数的增加,表面壳聚糖累计面积从0.9 mm2增加到4.5 mm2,达到其本体复合的比例.表面水接触角随着刻蚀次数的增加从91度减少到28度.细胞学实验表明刻蚀后表面的壳聚糖促进了成骨细胞在复合材料表面的粘附及生长.用激光表面选择性刻蚀可以提高复合材料表面生物活性的成分从而改善其生物活性.
参考文献
[1] | Velmathi S;Nagahata R;Sugiyama J;Takeuchi K .A rapid eco-friendly synthesis of poly(butylene succinate) by a direct polyesterification under microwave irradiation[J].Macromolecular rapid communications: Publishing the newsletters of the European Polymer Federation,2005(14):1163-1167. |
[2] | Bikiaris DN;Achilias DS .Synthesis of poly(alkylene succinate) biodegradable polyesters, Part II: Mathematical modelling of the polycondensation reaction[J].Polymer: The International Journal for the Science and Technology of Polymers,2008(17):3677-3685. |
[3] | Hiroyuki Takahashi;Teruaki Hayakawa;Mitsuru Ueda .Convenient Synthesis of Poly(butylene succinate)Catalyzed by Distannoxane[J].Chemistry Letters,2000(6):684-685. |
[4] | Correlo VM;Boesel LF;Bhattacharya M;Mano JF;Neves NM;Reis RL .Properties of melt processed chitosan and aliphatic polyester blends[J].Materials Science & Engineering, A. Structural Materials: Properties, Misrostructure and Processing,2005(1/2):57-68. |
[5] | Thomas Uppert;Akira Yabe;Alexander Wokaun .Laser Ablation of Doped Polymer Systems[J].Advanced Materials,1997(2):105-119. |
[6] | Yogeswaran U;Chen SM .Recent trends in the application of carbon nanotubes-polymer composite modified electrodes for biosensors: A review[J].Analytical Letters,2008(2):210-243. |
[7] | 吴刚,王迎军,陈晓峰,叶建东,魏坤,LEON Betty.193 nm激光引发PET表面的化学接枝[J].高等学校化学学报,2008(08):1655-1659. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分:
-
10%
-
20%
-
30%
-
40%
-
50%