通过无皂乳液聚合得到不同丙烯酸(AAc)含量的交联N-异丙基丙烯酰胺-丙烯酸共聚物(P(NIPAM-co-AAc))微凝胶,利用原子力显微镜(AFM)对其形态和环境敏感性进行了分析.结果发现,该凝胶粒子大小均一,直径约800nm;当环境温度由15 ℃升至50 ℃时,粒子的体积缩小,这表明P(NIPAM-co-AAc)微凝胶具有温度敏感性.
参考文献
| [1] | 李亚娜,霍东霞,王红英,钱庆文.水凝胶作为胰岛素控释系统载体的研究进展[J].中国医药工业杂志,2005(07):438-441. |
| [2] | HOFFMAN A S;AFRASSIABI A;CHANG D L.[J].Journal of Controlled Release,1986(04):213. |
| [3] | Pelton R. .Temperature-sensitive aqueous microgels[J].Advances in Colloid and Interface Science,2000(1):1-33. |
| [4] | Kawaguchi H. .Functional polymer microspheres [Review][J].Progress in Polymer Science,2000(8):1171-1210. |
| [5] | Harmon ME.;Kucking D.;Frank CW. .Photo-cross-linkable PNIPAAm copolymers. 5. Mechanical properties of hydrogel layers[J].Langmuir: The ACS Journal of Surfaces and Colloids,2003(26):10660-10665. |
| [6] | Matzelle TR.;Geuskens G.;Kruse N. .Elastic properties of poly(N-isopropylacrylamide) and poly(acrylamide) hydrogels studied by scanning force microscopy[J].Macromolecules,2003(8):2926-2931. |
| [7] | Kazakov S.;Kaholek M.;Kudasheva D.;Teraoka I.;Cowman MK.;Levon K. .Poly(N-isopropylacrylamide-co-1-vinylimidazole) hydrogel nanoparticles prepared and hydrophobically modified in liposome reactors: Atomic force microscopy and dynamic light scattering study[J].Langmuir: The ACS Journal of Surfaces and Colloids,2003(19):8086-8093. |
| [8] | 李亚娜,霍东霞,钱庆文,刘玉坤.pH及温度敏感性N-异丙基丙烯酰胺-丙烯酸共聚微凝胶的制备与表征[J].合成橡胶工业,2005(03):222-222. |
| [9] | RDLER J;RADMACHER M;GAUB H E .[J].LANGMUIR,1994,10(09):3111. |
| [10] | De Cupere VM.;Rouxhet PG. .Collagen films adsorbed on native and oxidized poly(ethylene terephtalate): morphology after drying[J].Surface Science: A Journal Devoted to the Physics and Chemistry of Interfaces,2001(3):395-404. |
| [11] | 赵涛,蔡继业,王小燕.AFM针尖对胶原样品表面一种损伤现象的研究[J].现代科学仪器,2003(02):58-60. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%