在评价圆产膨体聚四氟乙烯的细胞毒性和预处理方法的优劣的基础上,寻找国产替代材料,并比较国产膨体聚四氟乙烯与进口材料的细胞毒性.采用MTT(四甲基偶氮唑蓝)法检测经过不同方法预处理的国产膨体聚四氟乙烯和进口材料的细胞毒性.按细胞毒性分级的国家标准对其进行分级,评价其细胞毒性.结果表明,以上各组材料毒性级别均为1级,即无细胞毒性.国产膨体聚四氟乙烯具有良好的细胞相容性,以高锰酸钾溶液进行预处理可获得最佳效果.
参考文献
| [1] | Waldman SR .Gore-Tex of augumentation of nasal dorsum:A preliminary report[J].Ann Restoration Surgery,1991,26:520-552. |
| [2] | Owsley TG;Taylor CO .The use of Gore-Tex for nasal augument-ation:A retrospective analysis of 106 patients[J].Plastic and Reconstructive Surgery,1994,94:241-248. |
| [3] | Neel HB .Implants of Gore-Tex:comparisons with Tefloncoated polytetrafluroethlene carbon and porous polyethylene implants[J].Archives of Otolaryngology,1983,109:427-433. |
| [4] | Mole B .The use of Gore-Tex implants in aesthetic surgery of the face[J].Plastic and Reconstructive Surgery,1992,90:200-206. |
| [5] | Lassus C .Gore-Tex implants for aesthetic surgery of the face[J].Plastic and Reconstructive Surgery,1993,91:1364-1366. |
| [6] | Maas CS;Gnepp DR;Bumpous J .Expanded polytetrafluoro-ethylene(Gore-Tex soft-tissue patch)in facial augmentation[J].Archives of Otolaryngology Head and Neck Surgery,1993,119:1008-1014. |
| [7] | Godin MS;Waldman SR;Johnson CM Jr .The use of expanded polytetrafluoroethylene(Gore-Tex)in rhinoplasty.A 6-year experience[J].Archives of Otolaryngology Head and Neck Surgery,1995,121:1131-1136. |
| [8] | 邹丽剑;薛淼;高景恒.生物材料在整形外科的应用[A].杭州:浙江科学技术出版社,1999:360-364. |
| [9] | Simme rmacher RK;Schakenraad JM;Bleichrodt RP .Reherniation after repair of the abdominal wall with expanded polytetrafluoro-ethylene[J].Journal of the American College of Surgeons,1994,178:613-6. |
| [10] | 郝和平.细胞毒性试验.医疗器械生物学评价标准实施指南[M].北京:中国标准出版社,2000:360-364. |
| [11] | 贾文英,史弘道.细胞毒性试验评价医用装置生物相容性的研究概况[J].实用美容整形外科杂志,2001(05):253-255. |
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