磷酸钙骨水泥(CPC)作为一种人工骨替代材料,以其良好的生物相容性和骨传导能力被广泛应用于人工关节置换的固定和骨缺损修复.但其存在固化时间较长、机械性能不足等缺点,使其应用在临床上受到一定限制,故需要对其进行复合改性研究.综述了近年CPC的复合改性研究,分别论述了添加无机离子改性、掺杂其它晶种、有机复合改性以及CPC的功能型应用.
参考文献
[1] | Brown W E;Chow L C.A new calcium phosphate water-setting cement[A].Ohio:American Ceramic Society,1986:352. |
[2] | 李峰,刘斌,赵信义,吴军正,李焰.含锶磷酸钙骨水泥的细胞毒性[J].中国现代医学杂志,2006(20):3080-3082. |
[3] | Guo Dagang;Xu Kewei;Zhao Xiaoyun et al.Development of a strontium-containing hydroxyapatite bone cement[J].Biomaterials,2005,26:4073. |
[4] | Miyamoto Y;Ishikawa k;Takechhi M et al.Tissue response to fast-setting calcium phosphate cement in bone[J].Journal of Biomedical Materials Research,1997,37(04):457. |
[5] | 蔡舒,姚康德,关勇辉.羟基磷灰石晶种对α-磷酸钙骨水泥水化的影响[J].硅酸盐学报,2003(01):108-112. |
[6] | Hockin H. K. Xu;Janet B. Quinn .Whisker-reinforced bioactive composites containing calcium phosphate cement fillers: Effects of filler ratio and surface treatments on mechanical properties[J].Journal of biomedical materials research, Part B. Applied biomaterials,2001(2):165-174. |
[7] | Miyamoto Y;Ishikawa K;Takechhi M et al.Tissue response to fast-setting calcium phosphate cement in bone[J].Journal of Biomedical Materials Research,1997,37(04):457. |
[8] | 吴文进,杨为中,周大利,马将,肖斌.碳纤维增强α-磷酸三钙骨水泥的研究[J].生物医学工程学杂志,2006(03):569-572. |
[9] | Xu HH;Quinn JB .Calcium phosphate cement containing resorbable fibers for short-term reinforcement and macroporosity.[J].Biomaterials,2002(1):193-202. |
[10] | Oreffo RO;Driessens FC;Planell JA;Triffitt JT .Growth and differentiation of human bone marrow osteoprogenitors on novel calcium phosphate cements.[J].Biomaterials,1998(20):1845-1854. |
[11] | Khairoun I.;Driessens FCM.;Planell JA.;Boltong MG. .EFFECT OF CALCIUM CARBONATE ON THE COMPLIANCE OF AN APATITIC CALCIUM PHOSPHATE BONE CEMENT[J].Biomaterials,1997(23):1535-1539. |
[12] | Dennis PLink;Juliette van den Dolder;Wouter J F M Jurgens .Mechanical evaluation of implanted calcium phosphate cement incorporated with PLGA microparticles[J].Biomaterials,2006,27:4941. |
[13] | 何菁萍,王明玺,张昭.聚合磷酸钙骨水泥的制备和性能研究[J].四川大学学报(工程科学版),2001(02):43-46. |
[14] | Wang X;Ma J;Wang Y;He B .Structural characterization of phosphorylated chitosan and their applications as effective additives of calcium phosphate cements.[J].Biomaterials,2001(16):2247-2255. |
[15] | 张利,李玉宝,周钢,吕国玉,左奕.纳米羟基磷灰石/壳聚糖复合骨水泥的固化机理研究[J].无机材料学报,2006(05):1197-1202. |
[16] | GENG Yanli,RUAN Ziwei,LI Dongxu.Preparation of a Novel Calcium Phosphate Cement Using N-methylene Phosphonic Chitosan as a Gelling Agent[J].武汉理工大学学报(材料科学版)英,2005(z1):304-307. |
[17] | Hua Liu;Hong Li;Cheng Wenjun .Novel injectable calcium phosphate/chitosan composites for bone substitute materials[J].Acta Biomaterialia,2006,2:557. |
[18] | Makoto Watanabe;Miyuki Tanaka;Makoto Sakurai et al.Development of calcium phosphate cement[J].European Ceramic Society,2006,26:549. |
[19] | Gbureck U.;Barralet JE.;Spatz K.;Grover LM.;Thull R. .Ionic modification of calcium phosphate cement viscosity. Part I: hypodermic injection and strength improvement of apatite cement[J].Biomaterials,2004(11):2187-2195. |
[20] | Ishikawa K;Miyamoto Y;Takechhi M et al.Nondecay type fast-setting calcium phosphate cement:hydroxyapatite puttay containing an increased amount of sodium alginate[J].Journal of Biomedical Materials Research,1997,36(03):393. |
[21] | Blom et al.Transforming growth factor-β 1 incorporation in an α-tricalcium phosphate/dicalcium phosphate dehydrate/tetracalcium phosphate monoxide cement:release characteristics and physicochemieal properties[J].Biomaterials,2002,23:1261. |
[22] | Quinten Ruhe P;Henriette C Kroese-Deutman .Bone inductive properties of rhBMP-2 loaded porous calcium phosphate cement implants in cranial defects in rabbits[J].BIOMATERIALS,2004,25:2123. |
[23] | 王正国.微创外科新概念[J].中华外科杂志,2002(01):13-13. |
[24] | 滕海军,周跃,初同伟,曹国永.注射型磷酸钙骨水泥和PMMA在椎体成形术中的生物力学研究[J].中国矫形外科杂志,2004(01):70-73. |
[25] | Hockin H K Xu;Michael D Weir;Elena F Burguera .Injectable and macroporous calcium phosphate cement scaffold[J].Biomaterials,2006,27:4279. |
[26] | 孙效棠,赵黎,胡蕴玉,李丹,杜俊杰,崔赓,毕龙.磷酸钙骨水泥载药核心块型重组合异种骨修复大段骨缺损的能力及其力学性能[J].中国临床康复,2004(14):2610-2612. |
[27] | Maria-Pau Ginebra;Tania Traykova;Josep A Planell .Calcium phosphate cements:Competitive drug carriers for the musculoskeletal system?[J].Biomaterials,2006,27:2171. |
[28] | Maria-Pan Ginebra;Tania Traykova;Josep A Planell .Calcium phosphate cements as bone drug delivery systems:A review[J].Journal of Controlled Release,2006,113:102. |
[29] | Almirall A.;Larrecq G.;Delgado JA.;Martinez S.;Planell JA.;Ginebra MP. .Fabrication of low temperature macroporous hydroxyapatite scaffolds by foaming and hydrolysis of an alpha-TCP paste[J].Biomaterials,2004(17):3671-3680. |
[30] | Xu HH;Quinn JB .Calcium phosphate cement containing resorbable fibers for short-term reinforcement and macroporosity.[J].Biomaterials,2002(1):193-202. |
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