利用磁控溅射合成具有一定特性的Ti-O薄膜,并采用Ar离子溅射刻蚀该薄膜表面.运用原子力显微镜(AFM),X射线衍射(XRD)对刻蚀后的薄膜表面微观形貌、微结构进行表征.结果表明:薄膜的结构未发生变化,表面的粗糙度减小.进一步的人脐静脉内皮细胞(HUVEC)种植实验表明:表面粗糙度的变化对内皮细胞的贴附、生长与增殖有很大的影响.
参考文献
| [1] | Huang N;Yang P;Chen X et al.Blood compatibility of amorphous titanium oxide films synthesized by ion beam enhanced deposition[J].Biomaterials,1998,19:771. |
| [2] | Huang N;Yang P;Leng YX;Chen JY;Sun H;Wang J;Wang GJ;Ding PD;Xi TF;Leng Y .Hemocompatibility of titanium oxide films.[J].Biomaterials,2003(13):2177-2187. |
| [3] | 陈俊英.Ti-O薄膜表面抗凝血及人脐静脉内皮细胞种植研究[M].北京:国材料研讨会,2002 |
| [4] | Tunstall A;Rober C E;Morton D P .Comparison of tissue factor and prostacyclin production by human umilical Vein endothelial cells on Dacron Vascalar protheses and Dacron smooth film[J].Journal of Biomedical Materials Research,1994,28:1233. |
| [5] | Derick C;Miller et al.Endothelial and vascular smooth muscle cell function on poly (Lactic-Co- Jlycolic acid)with nanostructured surface features[J].BIOMATERIALS,2004,25:53. |
| [6] | 陆海伟,路庆华,陈万涛,徐宏杰,印杰.聚合物材料表面纳米条纹对生物细胞生长的影响[J].高等学校化学学报,2003(12):2324-2326. |
| [7] | Ronalde Unger et al.Growth of human cells on a non-woren silk fibromin net a potential for use in tissue engineering[J].BIOMATERIALS,2004,25:1069. |
| [8] | Tze-Wen Chung et al.Enhancement of the growth of human endothelial cell by surface roughness at nanometere s cale[J].Biomedical Materials & Engineering,2003,24:465. |
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